Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells [PDF]
Background Secretion of human chorionic gonadotropin, especially its beta subunit by malignant trophoblastic tumors and varieties of tumors of different origin is now well documented; however the role of hCG in tumorogenesis is still unknown.
Jarmolowski Artur +7 more
doaj +4 more sources
Regulation of human chorionic gonadotropin beta subunit expression in ovarian cancer [PDF]
Purpose Expression of human chorionic gonadotropin beta subunit by cancers is extensively documented, yet regulation of the multiple genes that can code for this protein is poorly understood.
Aleksandra Śliwa +9 more
doaj +3 more sources
Background Metastasis is a common feature of many advanced stage cancers and metastatic spread is thought to be responsible for cancer progression. Most cancer cells are localized in the primary tumor and only a small population of circulating tumor ...
Gąsiorowska Emilia +7 more
doaj +3 more sources
Mola hidatiforme e doença trofoblástica gestacional Hydatidiform mole and gestational trophoblastic disease [PDF]
A mola hidatiforme é uma complicação relativamente infrequente da gravidez, mas com potencial para evolução para formas que necessitam de tratamento sistêmico e podem ser ameaçadoras da vida.
Jurandyr Moreira de Andrade
doaj +4 more sources
Localization of human chorionic gonadotropin beta subunit transcripts in ovarian cancer tissue.
Recent studies demonstrated that besides placenta and malignant trophoblastic tumors, hCG and especially its beta-subunit is secreted by a varieties of tumors of different origin.
Jerzy B Warchoł +4 more
doaj +3 more sources
Comparison of four different analyzers for prenatal trisomy 21 risk [PDF]
Various analyzers are available for measuring first-trimester combined screening for trisomy 21 (T21) serum biomarkers (free-beta subunit of the human chorionic gonadotropin (β-hCG) and the pregnancy-associated plasma protein A (PAPP-A)).
García-Simón Natalia +3 more
doaj +2 more sources
The Association and diagnostic value between Maternal Serum Placental Markers and Placenta Previa [PDF]
Objective: This study aims to evaluate the correlation and diagnostic value of maternal serum placental markers: pregnancy-associated plasma protein-A (PAPP-A), free beta human chorionic gonadotropin (free β-hCG), and alpha fetoprotein (AFP) in relation ...
Panpan Ma, Tingting Hu, Yiming Chen
doaj +2 more sources
Predictive value of the maternal alpha-fetoprotein variant, L2, during the first trimester of pregnancy screening for fetal trisomy 21, trisomy 18, and neural tube defects [PDF]
Background To assess the predictive usefulness of maternal serum alpha fetoprotein variant L2 (AFP-L2) for fetal trisomy 21, trisomy 18, and neural tube abnormalities (NTDs) in early pregnancy screening.
Yiming Chen +4 more
doaj +2 more sources
Biochemical and ultrasonographic markers in fetal surveillance [PDF]
Introduction/Objective. Fetal growth restriction (FGR) is associated with increased fetal and neonatal mortality and morbidity. The study objective was to investigate the correlation of maternal blood biochemical markers routinely determined in the first
Kocijančić-Belović Dušica +2 more
doaj +1 more source
This study analyzed RNA expression of genes for three serum tumor markers, alpha fetoprotein (AFP), human chorionic gonadotropin (hCG), and lactate dehydrogenase (LDH), in patients with testicular germ cell tumors (TGCT) type 2. The gene AFP encodes AFP,
Finn Edler von Eyben +2 more
doaj +1 more source

