Intracellular folding pathway of human chorionic gonadotropin beta subunit.
Few experimental models have been used to investigate how proteins fold inside a cell. Using the formation of disulfide bonds as an index of conformational changes during protein folding, we have developed a unique system to determine the intracellular folding pathway of the beta subunit of human chorionic gonadotropin (hCG).
J R, Huth +3 more
openaire +2 more sources
Extragonadal LH/hCG action-Not yet time to rewrite textbooks [PDF]
Gonadotropins are indispensable in both sexes in the regulation of gonadal sex steroid production and gametogenesis. In addition to their well-established classical actions, numerous recent publications have indicated the presence and function of ...
Ahtiainen, Petteri +5 more
core +3 more sources
Genetic models for the study of luteinizing hormone receptor function [PDF]
The luteinizing hormone/chorionic gonadotropin receptor (LHCGR) is essential for fertility in men and women. LHCGR binds luteinizing hormone (LH) as well as the highly homologous chorionic gonadotropin.
Narayan, Prema
core +10 more sources
Pulmonary Metastatic Choriocarcinoma in a Patient with Ectopic Pregnancy [PDF]
Gestational trophoblastic tumor (GTT) most commonly follows a molar pregnancy. In fact, it can occur following gestational events such as induced or spontaneous abortion, ectopic pregnancy, and term pregnancy.
Fahimeh Nokhostin +2 more
doaj +1 more source
The Pathogenic TSH β-Subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR [PDF]
1) Background: Central congenital hypothyroidism (CCH) is a rare endocrine disorder that can be caused by mutations in the β-subunit of thyrotropin (TSHB).
Biebermann, Heike +6 more
core +1 more source
Beta-HCG secretion by a pulmonary pleomorphic carcinoma: A case report
Ectopic secretion of beta-subunit of human chorionic gonadotropin (β-HCG) in pulmonary pleomorphic carcinoma is remarkably rare. Such unusual ectopic hormone production by lung cancer may be initially misinterpreted as extragonadal choriocarcinoma or ...
Magno Dinis de Sousa +6 more
doaj +1 more source
Diagnostic validity of a marker model of first trimester in pregnancy in prediction of birth weight [PDF]
Background/Aim. Nowadays, low birth weight is considered to be one of the main causes of cardiovascular diseases or metabolic syndrome occurring later in life.
Vujović Slavica +3 more
doaj +1 more source
Biological functions of hCG and hCG-related molecules [PDF]
Background hCG is a term referring to 4 independent molecules, each produced by separate cells and each having completely separate functions. These are hCG produced by villous syncytiotrophoblast cells, hyperglycosylated hCG produced by cytotrophoblast ...
Laurence A Cole
core +1 more source
Various carboxyl-terminal peptides of hCG-β were prepared from the corresponding blocked peptides by TFA treatment followed by hydrogenation. The prepared peptides were tested for inhibitory action on the binding between 125I-hCG and the antiserum against the carboxyl-terminal portion of hCG-β.
K, Kawasaki +8 more
openaire +2 more sources
Making of a unique birth control vaccine against hCG with additional potential of therapy of advanced stage cancers and prevention of obesity and insulin resistance [PDF]
Reviewed is the work which led to the development of a unique vaccine that prevents pregnancy in sexually active women without impairment of ovulation and block of their making normally their sex steroid hormones. Being given that hCG is not expressed by
Atrey, Nishu +9 more
core +2 more sources

