The crystal structure of the β subunit of luteinizing hormone and a model for the intact hormone
Current Research in Structural Biology, 2019 The β subunit of bovine luteinizing hormone (LH) was crystallized and its structure solved to 3.15 Å resolution by molecular replacement using human chorionic gonadotropin (hCG) β subunit as search model. The asymmetric unit contains two copies of the β
Steven B. Larson, Alexander McPherson
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Postmenopausal pregnancy: A case report
Iranian Journal of Nursing and Midwifery Research, 2020 Abnormal vaginal bleeding is one of the complaints of women during menopause. Various diseases such as endometrial atrophy, polyps, and endometrial cancers may lead to postmenopausal vaginal bleeding.
Rafat Mirsafi, Mahtab Attarha
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Extragonadal LH/hCG action-Not yet time to rewrite textbooks [PDF]
, 2007 Gonadotropins are indispensable in both sexes in the regulation of gonadal sex steroid production and gametogenesis. In addition to their well-established classical actions, numerous recent publications have indicated the presence and function of ...
Ahtiainen, Petteri +5 more
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Intracellular folding pathway of human chorionic gonadotropin beta subunit.
Journal of Biological Chemistry, 1992 Few experimental models have been used to investigate how proteins fold inside a cell. Using the formation of disulfide bonds as an index of conformational changes during protein folding, we have developed a unique system to determine the intracellular folding pathway of the beta subunit of human chorionic gonadotropin (hCG).
J R, Huth +3 more
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Pulmonary Metastatic Choriocarcinoma in a Patient with Ectopic Pregnancy [PDF]
Journal of Midwifery & Reproductive Health, 2017 Gestational trophoblastic tumor (GTT) most commonly follows a molar pregnancy. In fact, it can occur following gestational events such as induced or spontaneous abortion, ectopic pregnancy, and term pregnancy.
Fahimeh Nokhostin +2 more
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Beta-HCG secretion by a pulmonary pleomorphic carcinoma: A case report
Respiratory Medicine Case Reports, 2021 Ectopic secretion of beta-subunit of human chorionic gonadotropin (β-HCG) in pulmonary pleomorphic carcinoma is remarkably rare. Such unusual ectopic hormone production by lung cancer may be initially misinterpreted as extragonadal choriocarcinoma or ...
Magno Dinis de Sousa +6 more
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Diagnostic validity of a marker model of first trimester in pregnancy in prediction of birth weight [PDF]
Vojnosanitetski Pregled, 2022 Background/Aim. Nowadays, low birth weight is considered to be one of the main causes of cardiovascular diseases or metabolic syndrome occurring later in life.
Vujović Slavica +3 more
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Making of a unique birth control vaccine against hCG with additional potential of therapy of advanced stage cancers and prevention of obesity and insulin resistance [PDF]
, 2014 Reviewed is the work which led to the development of a unique vaccine that prevents pregnancy in sexually active women without impairment of ovulation and block of their making normally their sex steroid hormones. Being given that hCG is not expressed by
Atrey, Nishu +9 more
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Chemical and Pharmaceutical Bulletin, 1982 Various carboxyl-terminal peptides of hCG-β were prepared from the corresponding blocked peptides by TFA treatment followed by hydrogenation. The prepared peptides were tested for inhibitory action on the binding between 125I-hCG and the antiserum against the carboxyl-terminal portion of hCG-β.
K, Kawasaki +8 more
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Stimulation of hCG protein and mRNA in first trimester villous cytotrophoblast cells in vitro by glycodelin A [PDF]
, 2005 Aim: Human chorionic gonadotropin (hCG) is produced by fetal trophoblast cells and secreted into maternal circulation mainly in the first trimester of pregnancy.
Albanese +19 more
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