Drug Testing and Analysis, EarlyView.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source
A case study on the potential angiogenic effect of human chorionic gonadotropin hormone in rapid progression and spontaneous regression of metastatic renal cell carcinoma during pregnancy and after surgical abortion [PDF]
, 2015 BACKGROUND: Treatment possibilities of metastatic renal cell carcinoma (mRCC) have recently changed dramatically prolonging the overall survival of the patients. This kind of development brings new challenges for the care of mRCC. CASE PRESENTATION: A 22
Endre Kálmán +5 more
core +1 more source
Use of the Abbott i‐STAT®1 point of care device for hCG quantification in early pregnancy
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objectives To evaluate the use of the Abbott i‐STAT®1 point‐of‐care‐test (POCT) device for measurement of human chorionic gonadotropin (hCG) to support the management of early pregnancy complications in a remote early pregnancy unit (EPU). Methods Women attending the EPU who required an hCG blood test were invited to take part in the study ...
Caroline Joyce +7 more
wiley +1 more source
Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]
, 1992 Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Gerbes, Alexander L. +4 more
core
Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone–receptor interactions [PDF]
, 1995 Background: Glycoprotein hormones influence the development and function of the ovary, testis and thyroid by binding to specific high-affinity receptors.
Buckler, David R +7 more
core +1 more source
Isolated asthenozoospermia: What should we know? A narrative review of literature
UroPrecision, EarlyView.ABSTRACT Male infertility contributes to 20%–70% of infertile couple cases worldwide. One of the key challenges in this area is asthenozoospermia or reduced sperm motility. A particular subset, known as isolated asthenozoospermia (iASZ), in which low motility occurs without abnormalities in sperm count or shape, often goes unnoticed and is not well ...
Ahmed Eissa +7 more
wiley +1 more source
Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies
Andrology, EarlyView.Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi +5 more
wiley +1 more source
Determination of the glycoforms of human chorionic gonadotropin b-core fragment by matrix-assisted laser desoption/ionisation time of flight mass spectrometry [PDF]
, 2000 Background: Metabolism of human chorionic gonadotropin (hCG) in the serum and kidney yields the terminal urinary product hCG ß-core fragment (hCGßcf), comprising two disulfide-linked peptides (ß6-ß40 and ß55-ß92) of which one (ß6-ß40) retains truncated N-
Iles, Ray K. +3 more
core
Luteinizing hormone receptor knockout mouse: What has it taught us?
Andrology, EarlyView.Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source
Human Chorionic Gonadotropin Beta Subunit Genes CGB1 and CGB2 are Transcriptionally Active in Ovarian Cancer [PDF]
International Journal of Molecular Sciences, 2013 Human chorionic gonadotropin beta subunit (CGB) is a marker of pregnancy as well as trophoblastic and nontrophoblastic tumors. CGB is encoded by a cluster of six genes, of which type II genes (CGB3/9, 5 and 8) have been shown to be upregulated in relation to type I genes (CGB6/7) in both placentas and tumors. Recent studies revealed that CGB1 and CGB2,
Grzegorz P. Walkowiak +3 more
openaire +3 more sources