Results 1 to 10 of about 10,508 (199)
Review on Abyssomicins: Inhibitors of the Chorismate Pathway and Folate Biosynthesis
Molecules, 2018 Antifolates targeting folate biosynthesis within the shikimate-chorismate-folate metabolic pathway are ideal and selective antimicrobials, since higher eukaryotes lack this pathway and rely on an exogenous source of folate.
Edmund Ellsworth +2 more
exaly +4 more sources
Chorismate mutase peptide antibody enables specific detection of Acanthamoeba.
PLoS ONE, 2021 Accurate and rapid diagnosis of Acanthamoeba keratitis (AK) is difficult. Although the diagnostic procedure for AK has improved, further development and effective diagnostic tool utilization for AK need to continue.
Hae-Ahm Lee +5 more
doaj +2 more sources
Frontiers in Bioengineering and Biotechnology, 2019 Tyrosol is extensively used in the pharmaceutical industry as an important natural product from plants. In this study, an exogenous pathway involved in catalyzing tyrosine to tyrosol was introduced into Saccharomyces cerevisiae. Furthermore, The pyruvate
Wei Guo +8 more
doaj +2 more sources
Agronomy, 2020 Both drought and salinity represent the greatest plant abiotic stresses in crops. Increasing plant tolerance against these environmental conditions must be a key strategy in the development of future agriculture.
Jorge Poveda, Poveda Jorge
exaly +2 more sources
Frontiers in Plant Science, 2020 Acidovorax citrulli (Ac) is a plant pathogenic bacterium that causes bacterial fruit blotch (BFB) in cucurbit crops. Despite its importance in the cucurbit industry, resistant cultivars/lines against BFB have not yet been identified.
Minyoung Kim +3 more
doaj +2 more sources
Engineering Pseudomonas taiwanensis for efficient chorismate-based production of mono- and dihydroxybenzoates [PDF]
Metabolic Engineering CommunicationsAromatics have many important applications in modern society but are traditionally produced in non-sustainable processes from fossil resources. Whole-cell biocatalysis bears great potential to provide a variety of aromatics from renewable carbon sources,
Franziska Kofler +4 more
doaj +2 more sources
Completion of the cytosolic post-chorismate phenylalanine biosynthetic pathway in plants
Nature Communications, 2019 Phenylalanine is mostly synthesized in plant plastids, but cytosolic transamination of phenylpyruvate also contributes. Here the authors show that a cytosolic chorismate mutase and a prephenate dehydratase encoded by an isoform of the plastidial ADT3 ...
Yichun Qian +5 more
doaj +2 more sources
Scientific Reports, 2017 3-deoxy-D-arabino-heptulosonate-7-phosphate-synthase (DAHPS) is the first enzyme of the shikimate pathway and is responsible for the synthesis of aromatic amino acids in microorganisms. This pathway is an attractive target for antimicrobial drugs.
Shivendra Pratap +6 more
doaj +2 more sources
A broadly conserved fungal chorismate mutase targets the plant shikimate pathway to regulate salicylic acid production and other secondary metabolites [PDF]
mBioThe molecular dynamics of plant-pathogen interactions are complex, involving a constant defense race between host plants and pathogens. Plants deploy antimicrobial metabolites and physiological responses to inhibit pathogens, while pathogens counteract ...
Dandan Shao +9 more
doaj +2 more sources
Integrated In Silico – In Vitro Study Investigating Dipeptides as Chorismate Synthase Modulators: Spotlight on Its Mechanism of Action [PDF]
Global ChallengesCampylobacter jejuni is a widespread foodborne pathogen causing campylobacteriosis, a disease leading to diarrhea, fever, and gastroenteritis, able to adapt to many niches.
Lorenzo Pedroni +4 more
doaj +2 more sources