Results 171 to 180 of about 10,527 (218)

A Theoretical Study of the Chorismate Synthase Reaction

Organic Letters, 2001
Density functional calculations (B3LYP/6-31+G(d,p)) were carried out to investigate the mechanism of the anti-1,4-elimination of phosphate from 5-enolpyruvylshikimate-3-phosphate 1 that is catalyzed by chorismate synthase. Of particular interest was the functional role of the reduced flavin cofactor. [reaction: see text]
O, Dmitrenko, H B, Wood, R D, Bach, B, Ganem   +3 more
openaire   +2 more sources

Nucleophile Selectivity of Chorismate‐Utilizing Enzymes

ChemBioChem, 2007
aeruginosa) catalyzes the conversion of chorismate to isochorismate (2) by nucleophilic addition of water to the C2 of chorismate, with loss of the C4 hydroxyl. This is then converted to salicylate (3) by isochorismate pyruvate lyase (e.g. , PchB in P. aeruginosa).
Olivier, Kerbarh, Alessio, Ciulli, Dimitri Y, Chirgadze, Tom L, Blundell, Chris, Abell   +4 more
openaire   +2 more sources

A new test for chorismate mutase activity

Analytical Biochemistry, 1978
Abstract Chorismate mutase (EC 5.4.99.5) catalyzes the conversion of chorismic acid to prephenic acid. A continuous test of the enzymatic activity is based on the decrease of the absorption of the substrate chorismate at 274 nm (1). In a sensitive but discontinuous test, prephenic acid, the product of the enzymatic reaction is converted to ...
openaire   +2 more sources

ChemInform Abstract: IMPROVED SYNTHESIS OF RACEMIC CHORISMIC ACID. CLAISEN REARRANGEMENT OF 4‐EPI‐CHORISMIC ACID AND DIMETHYL 4‐EPI‐CHORISMATE

Chemischer Informationsdienst, 1984
AbstractChorisminsäure (VIIIa) wird aus dem Ester (I) über die Stufen (II)‐(VIIb) dargestellt.
J. H. HOARE, P. P. POLICASTRO, G. A. BERCHTOLD   +2 more
openaire   +1 more source

Regulation of Chorismate-Derived Antibiotic Production

1979
Publisher Summary Antibiotic production is a dispensable function of the producing cell, which is a characteristic of plasmic-borne traits, such as sex, metal resistance, pathogenicity, and drug resistance. The pattern of antibiotic production in any medium is strongly influenced by the growth rate of the producing organism.
openaire   +2 more sources

Syntheses of chorismate analogs for investigation of structural requirements for chorismate mutase

1994
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1994. ; Includes bibliographical references. ; by Chang-Chung Cheng. ; Ph.D.
openaire   +1 more source

Biophysical and In-Silico Studies of Phytochemicals Targeting Chorismate Synthase from Drug-Resistant Moraxella Catarrhalis

The Protein Journal, 2020
Neetu Neetu, Monica Sharma, J. K. Mahto, Pravindra Kumar   +3 more
semanticscholar   +1 more source

Stereochemistry of chorismic acid biosynthesis

Journal of the American Chemical Society, 1969
R K, Hill, G R, Newkome
openaire   +2 more sources

chorismate, n.

2023
openaire   +1 more source

chorismic, adj.

2023
openaire   +1 more source