Results 161 to 170 of about 10,527 (218)
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Menaquinone Biosynthesis: Biochemical and Structural Studies of Chorismate Dehydratase.
Biochemistry, 2019Menaquinone (MK, vitamin K) is a lipid-soluble quinone that participates in the bacterial electron transport chain. In mammalian cells, vitamin K functions as an essential vitamin for the activation of several proteins involved in blood clotting and bone
N. Mahanta +6 more
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Analytical Biochemistry, 1977
Abstract Chorismate mutase (EC 5.4.99.5) from Streptomyces aureofaciens is bound virtually irreversibly by n -decylamine-substituted agarose and remains active when immobilized by hydrophobic binding. The enzyme is not eluted by buffers containing 1 m NaCl or 50% ethylene glycol.
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Abstract Chorismate mutase (EC 5.4.99.5) from Streptomyces aureofaciens is bound virtually irreversibly by n -decylamine-substituted agarose and remains active when immobilized by hydrophobic binding. The enzyme is not eluted by buffers containing 1 m NaCl or 50% ethylene glycol.
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Chorismate synthase of Neurospora crassa: A flavoprotein
Archives of Biochemistry and Biophysics, 1974Abstract Chorismate synthase is purified from Neurospora crassa. The final step is accomplished by preparative electrophoresis. Its purity is estimated at ≥90% on the basis of analytical polyacrylamide gel electrophoresis. The enzyme appears to be active in at least two multimeric states, with a subunit molecular weight of ~55,000.
G R, Welch, K W, Cole, F H, Gaertner
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QM/MM molecular modelling on mutation effect of chorismate synthase enzyme catalysis.
Journal of Molecular Graphics and Modelling, 2019Chorismate synthase (CS) catalyzes the conversion of 5-enolpyruvylshikimate-3-phosphate (EPSP) to chorismate which is a key intermediate in the biosynthesis of aromatic amino acids. CS enzyme is a new target for antibacterial drugs.
Narin Lawan +3 more
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Chorismate derived C6C1 compounds in plants
Planta, 2005The secondary metabolites are the products of interac tion of the producing organism with its environment and have a restricted occurrence. Many have economical importance as, e.g. drugs, antioxidants, flavors, fra grances, dyes, insecticides and pheromones (Verpoorte et al. 2002). Secondary metabolites can be classified according to their biosynthetic
Natali Rianika, Mustafa +1 more
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Properties of chorismate mutase ofStreptomyces venezuelae
Archiv für Mikrobiologie, 19721. Chorismate mutase, the first enzyme of the terminal biosynthetic pathway of phenylalanine and tyrosine has been purified 10 fold fromStreptomyces venezuelae. 2. The catalytic activity has a broad optimum between pH 6.6 and 7. The initial velocity data follow regular Michaelis-Menten kinetics with aKm of 3.8×10-4 M.
H, Görisch, F, Lingens
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Regulation of chorismate mutase in Saccharomyces cerevisiae
Molecular and General Genetics MGG, 1990The Saccharomyces cerevisiae ARO7 gene was cloned by screening a wild-type gene bank for complementation of an aro7 auxotrophic mutant. In vitro mutagenesis of the isolated plasmid (pJFB1) gave several transformants resistant to levels of the phenylalanine analogue 2-thienylalanine inhibitory to the wild-type transformant.
J F, Brown, I W, Dawes
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Structure of the Ustilago maydis chorismate mutase 1
, 2019Fungi-induced plant diseases affect global food security and plant ecology. The biotrophic fungus Ustilago maydis causes smut disease in maize (Zea mays) plants by secreting numerous virulence effectors that reprogram plant metabolism and immune ...
F. Altegoer, Wieland Steinchen, G. Bange
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Journal of the American Chemical Society, 1984
Unter Einsatz der markierten Substrate (III), (IV) bzw. (V), die zu diesem Zweck von den Autoren bereits (enzymatisch bzw. chemisch) synthetisiert worden sind, wird die enzymatische Claisen-Umlagerung von Chorismat (I) in Prephenat (II) untersucht; es wird gezeigt, das der enzymkatalysierte Prozes uber einen Ubergangszustand mit Sessel-ahnlicher ...
Steven G. Sogo +5 more
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Unter Einsatz der markierten Substrate (III), (IV) bzw. (V), die zu diesem Zweck von den Autoren bereits (enzymatisch bzw. chemisch) synthetisiert worden sind, wird die enzymatische Claisen-Umlagerung von Chorismat (I) in Prephenat (II) untersucht; es wird gezeigt, das der enzymkatalysierte Prozes uber einen Ubergangszustand mit Sessel-ahnlicher ...
Steven G. Sogo +5 more
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Chorismate synthase from malaria parasites is bifunctional enzyme.
Molecular and biochemical parasitology (Print), 2019Chorismate synthase (Cs) is the last enzyme of the main trunk of shikimate pathway and catalyzes formation of chorismate, a major aromatic metabolite precursor. We have previously reported that Cs is highly conserved across different Plasmodium sp.
H. Khera, S. Singh, Subhash Singh
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