Results 21 to 30 of about 4,684 (170)
Parasitism genes from phytoparasitic nematodes are thought to be essential for nematode invasion of the host plant, to help the nematode establish feeding sites, and to aid nematodes in the suppression of host plant defenses.
Sadia Bekal +2 more
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Completion of the cytosolic post-chorismate phenylalanine biosynthetic pathway in plants
Phenylalanine is mostly synthesized in plant plastids, but cytosolic transamination of phenylpyruvate also contributes. Here the authors show that a cytosolic chorismate mutase and a prephenate dehydratase encoded by an isoform of the plastidial ADT3 ...
Yichun Qian +5 more
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Hybrid RHF/MP2 geometry optimizations with the effective fragment molecular orbital method.
The frozen domain effective fragment molecular orbital method is extended to allow for the treatment of a single fragment at the MP2 level of theory. The approach is applied to the conversion of chorismate to prephenate by Chorismate Mutase, where the ...
Anders S Christensen +3 more
doaj +1 more source
Summary Tyrosol and its glycosylated product salidroside are important ingredients in pharmaceuticals, nutraceuticals and cosmetics. Despite the ability of Saccharomyces cerevisiae to naturally synthesize tyrosol, high yield from de novo synthesis ...
Huayi Liu +6 more
doaj +1 more source
Tyrosol is extensively used in the pharmaceutical industry as an important natural product from plants. In this study, an exogenous pathway involved in catalyzing tyrosine to tyrosol was introduced into Saccharomyces cerevisiae. Furthermore, The pyruvate
Wei Guo +8 more
doaj +1 more source
Metabolic engineering of Pseudomonas putida KT2440 to produce anthranilate from glucose
The Pseudomonas putida KT2440 strain was engineered in order to produce anthranilate (oAB, ortho-aminobenzoate), a precursor of the aromatic amino acid tryptophan, from glucose as sole carbon source. To enable the production of the metabolic intermediate
Jannis eKuepper +6 more
doaj +1 more source
Root-knot nematodes are obligate plant parasites that alter plant cell growth and development by inducing the formation of giant feeder cells. It is thought that nematodes inject secretions from their esophageal glands into plant cells while feeding, and
Kris N. Lambert +2 more
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Separation of inhibition and activation of the allosteric yeast chorismate mutase [PDF]
Yeast chorismate mutase (EC 5.4.99.5 ) shows homotropic activation by the substrate, allosteric activation by tryptophan, and allosteric inhibition by tyrosine. In this study mutants of chorismate mutase have been found that remain sensitive to one allosteric effector (tryptophan) but ...
G, Schnappauf, W N, Lipscomb, G H, Braus
openaire +2 more sources
Properties and Functional Analysis of Two Chorismate Mutases from Maritime Pine
Through the shikimate pathway, a massive metabolic flux connects the central carbon metabolism with the synthesis of chorismate, the common precursor of the aromatic amino acids phenylalanine, tyrosine, and tryptophan, as well as other compounds ...
Fernando de la Torre +6 more
doaj +1 more source
Herein, we observed that nuclear localization of phosphoglycerate dehydrogenase (PHGDH) is associated with poor prognosis in liver cancer, and Phgdh is required for liver cancer progression in a mouse model.
Hongwen Zhu +4 more
doaj +1 more source

