Results 21 to 30 of about 4,684 (170)

A Chorismate Mutase from the Soybean Cyst Nematode Heterodera glycines Shows Polymorphisms that Correlate with Virulence

open access: yesMolecular Plant-Microbe Interactions, 2003
Parasitism genes from phytoparasitic nematodes are thought to be essential for nematode invasion of the host plant, to help the nematode establish feeding sites, and to aid nematodes in the suppression of host plant defenses.
Sadia Bekal   +2 more
doaj   +1 more source

Completion of the cytosolic post-chorismate phenylalanine biosynthetic pathway in plants

open access: yesNature Communications, 2019
Phenylalanine is mostly synthesized in plant plastids, but cytosolic transamination of phenylpyruvate also contributes. Here the authors show that a cytosolic chorismate mutase and a prephenate dehydratase encoded by an isoform of the plastidial ADT3 ...
Yichun Qian   +5 more
doaj   +1 more source

Hybrid RHF/MP2 geometry optimizations with the effective fragment molecular orbital method.

open access: yesPLoS ONE, 2014
The frozen domain effective fragment molecular orbital method is extended to allow for the treatment of a single fragment at the MP2 level of theory. The approach is applied to the conversion of chorismate to prephenate by Chorismate Mutase, where the ...
Anders S Christensen   +3 more
doaj   +1 more source

Multi‐modular engineering of Saccharomyces cerevisiae for high‐titre production of tyrosol and salidroside

open access: yesMicrobial Biotechnology, 2021
Summary Tyrosol and its glycosylated product salidroside are important ingredients in pharmaceuticals, nutraceuticals and cosmetics. Despite the ability of Saccharomyces cerevisiae to naturally synthesize tyrosol, high yield from de novo synthesis ...
Huayi Liu   +6 more
doaj   +1 more source

Rational Engineering of Chorismate-Related Pathways in Saccharomyces cerevisiae for Improving Tyrosol Production

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Tyrosol is extensively used in the pharmaceutical industry as an important natural product from plants. In this study, an exogenous pathway involved in catalyzing tyrosine to tyrosol was introduced into Saccharomyces cerevisiae. Furthermore, The pyruvate
Wei Guo   +8 more
doaj   +1 more source

Metabolic engineering of Pseudomonas putida KT2440 to produce anthranilate from glucose

open access: yesFrontiers in Microbiology, 2015
The Pseudomonas putida KT2440 strain was engineered in order to produce anthranilate (oAB, ortho-aminobenzoate), a precursor of the aromatic amino acid tryptophan, from glucose as sole carbon source. To enable the production of the metabolic intermediate
Jannis eKuepper   +6 more
doaj   +1 more source

Cloning and Characterization of an Esophageal-Gland-Specific Chorismate Mutase from the Phytoparasitic Nematode Meloidogyne javanica

open access: yesMolecular Plant-Microbe Interactions, 1999
Root-knot nematodes are obligate plant parasites that alter plant cell growth and development by inducing the formation of giant feeder cells. It is thought that nematodes inject secretions from their esophageal glands into plant cells while feeding, and
Kris N. Lambert   +2 more
doaj   +1 more source

Separation of inhibition and activation of the allosteric yeast chorismate mutase [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
Yeast chorismate mutase (EC 5.4.99.5 ) shows homotropic activation by the substrate, allosteric activation by tryptophan, and allosteric inhibition by tyrosine. In this study mutants of chorismate mutase have been found that remain sensitive to one allosteric effector (tryptophan) but ...
G, Schnappauf, W N, Lipscomb, G H, Braus
openaire   +2 more sources

Properties and Functional Analysis of Two Chorismate Mutases from Maritime Pine

open access: yesCells
Through the shikimate pathway, a massive metabolic flux connects the central carbon metabolism with the synthesis of chorismate, the common precursor of the aromatic amino acids phenylalanine, tyrosine, and tryptophan, as well as other compounds ...
Fernando de la Torre   +6 more
doaj   +1 more source

Elevated Nuclear PHGDH Synergistically Functions with cMyc to Reshape the Immune Microenvironment of Liver Cancer

open access: yesAdvanced Science, 2023
Herein, we observed that nuclear localization of phosphoglycerate dehydrogenase (PHGDH) is associated with poor prognosis in liver cancer, and Phgdh is required for liver cancer progression in a mouse model.
Hongwen Zhu   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy