Results 91 to 100 of about 101,649 (294)

Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou, Li Dong, Yu‐Hang Yang, Yuan He, Xiao‐Zhen Wang, Han‐Qing Zhao, Rui‐Heng Zhang, Jost B. Jonas, Wen‐Bin Wei   +8 more
wiley   +1 more source

Efficacy of simultaneous VEGF‐A/ANG‐2 neutralization in suppressing spontaneous choroidal neovascularization

EMBO Molecular Medicine, 2019
This study independently confirms in vivo in the JR5558 mouse model of aberrant retinal angiogenesis, that simultaneous VEGF‐A and ANG‐2 neutralization using a bispecific anti‐VEGF‐A/ANG‐2 antibody reduces vascular leakage, immune reactivity and ...
R. Foxton, S. Uhles, S. Grüner, Franco Revelant, C. Ullmer   +4 more
semanticscholar   +1 more source

Comparative efficacy of intravitreal anti‐VEGF therapy for neovascular age‐related macular degeneration: A systematic review with network meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract The aim of this review was to evaluate the comparative efficacy of intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) therapy for neovascular AMD. We searched 12 literature databases for randomised clinical trials (RCT) on anti‐VEGF therapy for neovascular AMD and extracted data on: change from baseline to 12 months in best ...
Emilie T. S. Butler, Andreas Arnold‐Vangsted, Marianne G. Schou, Rodrigo Anguita, Jakob Bjerager, Enrico Borrelli, Lasse J. Cehofski, Lorenzo Ferro Desideri, Elon H. C. van Dijk, Carsten Faber, Jakob Grauslund, Javad N. Hajari, Josef Huemer, Oliver N. Klefter, Marie Krogh Nielsen, M. Cem Sabaner, Miklos Schneider, Yousif Subhi   +17 more
wiley   +1 more source

Erythropoietin Signaling Increases Choroidal Macrophages and Cytokine Expression, and Exacerbates Choroidal Neovascularization

Scientific Reports, 2018
Erythropoietin (EPO) is recognized for neuroprotective and angiogenic effects and has been associated with aging and neovascular age-related macular degeneration (AMD).
C. Bretz, V. Divoký, J. Prchal, Eric Kunz, Aaron B. Simmons, Haibo Wang, M. Hartnett   +6 more
semanticscholar   +1 more source

Multiple choroidal osteomas in a boy – a rare presentation: a case report

Journal of Medical Case Reports, 2019
Background Choroidal osteoma is rare clinical entity of unknown etiology, characterized by formation of mature cancellous bone within the choroid. It typically affects young females, with no racial predilection.
Arup Deuri, Deepanjan Ghosh, Jayant Ekka, Vijaya Agarwalla   +3 more
doaj   +1 more source

Automated segmentation and extraction of posterior eye segment using OCT scans [PDF]

arXiv, 2021
This paper proposes an automated method for the segmentation and extraction of the posterior segment of the human eye, including the vitreous, retina, choroid, and sclera compartments, using multi-vendor optical coherence tomography (OCT) scans. The proposed method works in two phases.
arxiv  

Outcome and safety of multiple photodynamic therapy sessions in chronic central serous chorioretinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose This study evaluates the effectiveness and safety of multiple PDT sessions for cases of persistent and recurrent subretinal fluid (SRF) in chronic central serous chorioretinopathy (CSC). Methods This multicentre, retrospective cohort study included patients aged ≥18 years with chronic CSC who received at least two sessions of PDT at ...
Jennifer M. Chang‐Wolf, Elon H. C. van Dijk, Kamal el Boujdaini, Mitchel van Straaten, Thomas J. van Rijssen, Reinier O. Schlingemann, Camiel J. F. Boon, Roselie M. H. Diederen   +7 more
wiley   +1 more source

Choroidal ischemia drives macular neovascularization in persistent placoid maculopathy

American Journal of Ophthalmology Case Reports, 2022
Purpose: To describe a case of persistent placoid maculopathy (PPM) complicated by macular neovascularization (MNV) that developed in areas of prior choroidal ischemia as illustrated with sequential optical coherence tomography angiography. Observations:
Meira Fogel Levin, Alice Wong, David Sarraf   +2 more
doaj  

EFFICACY AND SAFETY OF RANIBIZUMAB FOR THE TREATMENT OF CHOROIDAL NEOVASCULARIZATION DUE TO UNCOMMON CAUSE

Retina, 2017
Purpose: To evaluate the efficacy and safety of ranibizumab 0.5 mg in adult patients with choroidal neovascularization because of an uncommon cause enrolled in the 12-month MINERVA study. Methods: In this Phase III, double-masked study, adult (≥18 years)
T. Lai, G. Staurenghi, P. Lanzetta, F. Holz, S. H. Melissa Liew, Sabine Desset-Brèthes, H. Staines, P. Hykin   +7 more
semanticscholar   +1 more source

Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the AIDA Network Uveitis Registry

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano, Alejandra de‐la‐Torre, Silvana Guerriero, Stefania Costi, Gaafar Ragab, Maria Pia Paroli, Emanuela Del Giudice, Luciana Breda, Saverio La Bella, Marco Cattalini, Maria Cristina Maggio, Alex Fonollosa, Ester Carreño, Maria Tarsia, Rosanna Dammacco, Soad Hashad, Antonio Vitale, Lampros Fotis, Stefano Gentileschi, Francesca Minoia, Germán Mejía‐Salgado, Halah Etayari, Paola Saboya‐Galindo, María Andrea Bernal‐Valencia, Adele Civino, Maria Sole Chimenti, Valeria Caggiano, Maria Francesca Gicchino, Jurgen Sota, Angela Mauro, Giuseppe Lopalco, Kalpana Babu Murthy, Mohamed Tharwat Hegazy, Vishali Gupta, Francesco La Torre, Rana Hussein Amin, Bruno Frediani, Gian Marco Tosi, Luca Cantarini, Claudia Fabiani, on behalf of the AIDA Network   +40 more
wiley   +1 more source