Results 91 to 100 of about 121,184 (301)

En-face optical coherence tomography in the diagnosis and management of age-related macular degeneration and polypoidal choroidal vasculopathy [PDF]

open access: yes, 2015
published_or_final_versio
Chhablani, J   +7 more
core   +1 more source

CCR3 and Choroidal Neovascularization

open access: yesPLoS ONE, 2011
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly in industrialized countries. The "wet" AMD, characterized by the development of choroidal neovacularization (CNV), could result in rapid and severe loss of central vision.
Yiwen Li   +5 more
openaire   +4 more sources

Longitudinal changes in choroidal thickness in high myopia: Correlation with maculopathy progression and visual outcomes

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate longitudinal changes in choroidal thickness (CT) in highly myopic eyes and their correlation with myopic maculopathy progression and visual outcomes. Methods Retrospective cohort study on 1228 eyes from 781 highly myopic patients with a minimum 5‐year follow‐up (mean 11.5 ± 3.1 years).
Matteo Mario Carlà   +8 more
wiley   +1 more source

Knockdown of the Placental Growth Factor Gene Inhibits Laser Induced Choroidal Neovascularization in a Murine Model

open access: yesJournal of Ophthalmic & Vision Research, 2013
Purpose: To evaluate the effect of placental growth factor (PlGF) gene knockdown in a murine model of laser-induced choroidal neovascularization. Methods: Choroidal neovascularization was induced in the left eyes of 11 mice by infrared laser.
Ramin Nourinia   +5 more
doaj  

Intravitreal Ranibizumab in the Treatment of Butterfly-Shaped Pattern Dystrophy Associated with Choroidal Neovascularization: A Case Report

open access: yesCase Reports in Ophthalmology, 2012
Purpose: To present and document the effectiveness of intravitreal ranibizumab in the treatment of patients with choroidal neovascularization due to butterfly-shaped pattern dystrophy (PD) of the macula. Methods: Three intravitreal ranibizumab injections
Theodoros Empeslidis   +3 more
doaj   +1 more source

Retinal pigment epithelial tears after intravitreal bevacizumab injection for exudative age-related macular degeneration. [PDF]

open access: yes, 2008
PURPOSE: To determine the incidence of and the risk factors for the development of retinal pigment epithelial (RPE) tears after intravitreal bevacizumab (Avastin) injection for the treatment of exudative age-related macular degeneration (AMD). METHODS: A
Brod, Roy   +5 more
core   +2 more sources

Efficacy of simultaneous VEGF‐A/ANG‐2 neutralization in suppressing spontaneous choroidal neovascularization

open access: yesEMBO Molecular Medicine, 2019
This study independently confirms in vivo in the JR5558 mouse model of aberrant retinal angiogenesis, that simultaneous VEGF‐A and ANG‐2 neutralization using a bispecific anti‐VEGF‐A/ANG‐2 antibody reduces vascular leakage, immune reactivity and ...
R. Foxton   +4 more
semanticscholar   +1 more source

Choroidal neovascular membrane.

open access: yesIndian journal of ophthalmology, 1998
Choroidal neovascular membrane in the macular area is one of the leading causes of severe visual loss. Usually a manifestation in elderly population, it is often associated with age-related macular degeneration. The current mainstay of management is early diagnosis, usually by fundus examination, aided by angiography and photocoagulation in selected ...
Bhatt Nitul   +3 more
openaire   +2 more sources

The prechoroidal cleft in neovascular age‐related macular degeneration

open access: yesActa Ophthalmologica, EarlyView.
Abstract The prechoroidal cleft is a lenticular, hypo‐reflective space on optical coherence tomography imaging, located between a band of fibrovascular material underneath the retinal pigment epithelium (RPE) and Bruch's membrane. It occurs in 8%–22% of neovascular age‐related macular degeneration (nAMD) eyes, most often with macular neovascularization
Niels J. Brouwer   +3 more
wiley   +1 more source

Galectin‐1 promotes choroidal neovascularization and subretinal fibrosis mediated via epithelialmesenchymal transition

open access: yesThe FASEB Journal, 2018
VEGFA and TGF‐β are known major angiogenic and fibrogenic factors. Galectin‐1, encoded by lectin, galactoside‐binding, soluble (LGALS)1, has attracted growing attention for its facilitatory role in angiogenesis and fibrosis through its modification of ...
Di Wu   +5 more
semanticscholar   +1 more source

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