Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao+5 more
wiley +1 more source
Choroidal Osteoma with Choroidal Neovascularization and Focal Choroidal Excavation
A 28-year-old female presented with recent onset of metamorphopsia in left eye. Best corrected visual acuity was 20/20 in right eye and 20/600 in left eye.
Rajwinder Kaur+4 more
doaj +1 more source
Ranibizumab e bevacizumab intravítreo no tratamento da neovascularização de coróide extrafoveal da degeneração macular relacionada à idade [PDF]
PURPOSE: To investigate the efficacy of vascular endothelial growth factor-specific (VEGF) monoclonal antibodies in the treatment of choroidal neovascularization secondary to age-related macular degeneration (AMD) that does not extend beneath the foveal ...
Amaro, Miguel Hage, Roller, Aaron Brock
core +3 more sources
Lactic Acid Upregulates VEGF Expression in Macrophages and Facilitates Choroidal Neovascularization.
Purpose Lactic acid, the end product of glycolysis, has emerged as an immune-modulating metabolite in various diseases. In this study, we aimed to examine whether lactic acid contributes to the disease pathogenesis of choroidal neovascularization (CNV ...
Juha Song+11 more
semanticscholar +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs+12 more
wiley +1 more source
Purpose: To present and document the effectiveness of intravitreal ranibizumab in the treatment of patients with choroidal neovascularization due to butterfly-shaped pattern dystrophy (PD) of the macula. Methods: Three intravitreal ranibizumab injections
Theodoros Empeslidis+3 more
doaj +1 more source
Evaluation of 10 AMD Associated Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes. [PDF]
Choroidal neovascularization (CNV) commonly occurs in age related macular degeneration and pathological myopia patients. In this study we conducted a case-control prospective study including 431 participants.
Alvaro Velazquez-Villoria+10 more
doaj +1 more source
Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]
Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H.+2 more
core
Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans
Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou+8 more
wiley +1 more source
Choroidal neovascularization after intraocular foreign body
Ester Fernández-López, Mari Carmen Desco-Esteban, Adriana Fandiño-López, Mikhail Hernández-Díaz, Amparo NaveaDepartment of Vitreoretinal Diseases, FISABIO Oftalmología Médica, Valencia ...
Fernández-López E+4 more
doaj