Results 31 to 40 of about 574,116 (318)

Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity [PDF]

, 2011
Genomic maps of chromatin modifications have provided evidence for the partitioning of genomes into domains of distinct chromatin states, which assist coordinated gene regulation.
West, A., Ma, M.K-W., Adam G West, Heath, C., Carol Heath, Adam G. West, Meiji Kit-Wan Ma, Hair, A., Alan Hair   +8 more
core   +1 more source

Histone methylation by PRC2 is inhibited by active chromatin marks [PDF]

, 2013
Chromatin modifiers serve as regulatory switches that control the cell cycle, maintain pluripotency and drive differentiation and development. Positive feedback mechanisms help to pass on transcriptional information from one generation of cells to the ...
Schmitges, Frank W.
core   +1 more source

Chromatin-contact atlas reveals disorder-mediated protein interactions and moonlighting chromatin-associated RBPs.

, 2022
RNA-binding proteins (RBPs) play diverse roles in regulating co-transcriptional RNA-processing and chromatin functions, but our knowledge of the repertoire of chromatin-associated RBPs (caRBPs) and their interactions with chromatin remains limited. Here,
Karen Davey (11932673), Sebastian Steinhauser (5385871), Julian A Zagalak (8989769), Sviatoslav Sidorov (5504714), Mahmoud-Reza Rafiee (11932670), Nicholas M Luscombe (8114756), Jernej Ule (115588)   +6 more
core   +1 more source

Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites

Scientific Reports, 2017
Activation-induced cytidine deaminase (AID) triggers antibody diversification in B cells by catalysing deamination and subsequently mutating immunoglobulin (Ig) genes. Association of AID with RNA Pol II and occurrence of epigenetic changes during Ig gene
Virginia C. Rodríguez-Cortez, Paloma Martínez-Redondo, Francesc Català-Moll, Javier Rodríguez-Ubreva, Antonio Garcia-Gomez, Ganesh Poorani-Subramani, Laura Ciudad, Henar Hernando, Arantxa Pérez-García, Carlos Company, José M. Urquiza, Almudena R. Ramiro, Javier M. Di Noia, Alejandro Vaquero, Esteban Ballestar   +14 more
doaj   +1 more source

Perturbation of chromatin structure globally affects localization and recruitment of splicing factors [PDF]

, 2012
Chromatin structure is an important factor in the functional coupling between transcription and mRNA processing, not only by regulating alternative splicing events, but also by contributing to exon recognition during constitutive splicing.
Risso, Guillermo, J, Risso Guillermo J., Lleres, D, Jernej Ule, Ignacio E. Schor (120406), Llères, David, Llères David, Pawellek, A., Ule, J., Kornblihtt Alberto R., Schor, Ignacio, E, Risso, GJ, Ule, Jernej, Lamond, Angus I.; id_orcid, Lamond, A.I., Alberto R. Kornblihtt (120413), Lamond, Angus, I, Kornblihtt, Alberto, R, Pawellek, Andrea, Andrea Pawellek, Alberto R Kornblihtt, David Llères (68840), Guillermo J. Risso (120408), Andrea Pawellek (120410), Risso, Guillermo J., Schor*, I.E., Schor, I.E., Lamond Angus I., Schor, Ignacio E., Ule, J, Ule Jernej, Risso, G.J., David Llères, Kornblihtt, A.R., Ignacio E Schor, Pawellek Andrea, Lleres*, D., Lamond, AI, Guillermo J Risso, Angus I Lamond, Kornblihtt, Alberto R., Llères, D., Schor Ignacio E., Pawellek, A, Schor, IE, Angus I. Lamond (13065), Kornblihtt, AR, Jernej Ule (115588)   +47 more
core   +1 more source

Dynamics of subnuclear chromatin organization during "C. elegans" development : a role for H3K9 methylation [PDF]

, 2012
In eukaryotic cells, DNA is packaged into chromatin. This imposes an accessibility barrier to all genetic processes, while at the same time offering the means for tight control.
Towbin, Benjamin Daniel
core   +1 more source

Nucleolus and chromatin [PDF]

Histochemistry and Cell Biology, 2018
The nucleolus as site of ribosome biogenesis holds a pivotal role in cell metabolism. It is composed of ribosomal DNA (rDNA), which is present as tandem arrays located in nucleolus organizer regions (NORs). In interphase cells, rDNA can be found inside and adjacent to nucleoli and the location is indicative for transcriptional activity of ribosomal ...
Christian Schöfer, Klara Weipoltshammer
openaire   +2 more sources

Recruitment of Oct4 protein to UV-damaged chromatin in embryonic stem cells. [PDF]

, 2011
BACKGROUND: Oct4 is a specific marker of embryonic stem cell (ESC) pluripotency. However, little is known regarding how Oct4 responds to DNA damage. Here, we investigated whether Oct4 recognizes damaged chromatin in mouse ESCs stably expressing GFP-Oct4.
Kozubek, Stanislav, Foltankova, Veronika, Stanislav Kozubek, Gabriela Šustáčková, Lenka Stixová, Stixová Lenka, Soňa Legartová, Bartova, Eva, Veronika Foltánková, Kozubek Stanislav, Bártová Eva, Legartová Soňa, Foltánková Veronika, Stixova, Lenka, Legartova, Sona, Eva Bártová, Sustackova, Gabriela, Šustáčková Gabriela   +17 more
core   +1 more source

Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle

Scientific Reports, 2021
Chromatin configuration influences gene expression in eukaryotes at multiple levels, from individual nucleosomes to chromatin domains several Mb long.
John A. Halsall, Simon Andrews, Felix Krueger, Charlotte E. Rutledge, Gabriella Ficz, Wolf Reik, Bryan M. Turner   +6 more
doaj   +1 more source

Chromatin Dynamics [PDF]

Annual Review of Biophysics, 2010
The expression patterns of many protein-coding genes are orchestrated in response to exogenous stimuli, as well as cell-type-specific developmental programs. In recent years, researchers have shown that dynamic chromatin movements and interactions in the nucleus play a crucial role in gene regulation.
Michael R, Hübner, David L, Spector
openaire   +2 more sources