Results 221 to 230 of about 94,335 (243)

Chromatin loops, illegitimate recombination, and genome evolution

BioEssays, 2009
AbstractChromosomal rearrangements frequently occur at specific places (“hot spots”) in the genome. These recombination hot spots are usually separated by 50–100 kb regions of DNA that are rarely involved in rearrangements. It is quite likely that there is a correlation between the above‐mentioned distances and the average size of DNA loops fixed at ...
Omar L, Kantidze, Sergey V, Razin
openaire   +2 more sources

Analysis of Chromatin Interaction and Accessibility by Trac-Looping

2023
Spatial organization of the genome modulates pivotal biological processes. The emerging new technologies have provided novel insights into genome structure and its role in regulating cell activities. To examine the genome-wide chromatin interactions at accessible chromatin regions, we developed a DNA transposase-mediated analysis of chromatin looping ...
Shuai, Liu, Qingsong, Tang, Keji, Zhao
openaire   +2 more sources

BIOLOGICAL CONSEQUENCES OF CHROMATIN LOOPING IN PERICENTRIC CHROMATIN

2018
During mitosis, replicated sister chromatids are attached to opposite sides of a microtubule spindle at their centromeres in a process called biorientation. The proteinaceous structure that links centromeres, a region of the chromosome, to the spindle is called the kinetochore.
openaire   +1 more source

Chromatin loops and transcriptional regulation.

Critical reviews in eukaryotic gene expression, 1992
The existence of a supermolecular structure in the eukaryotic nucleus, involving loops of chromatin attached at irregularly spaced points to the nuclear matrix, is now well established. Quite a bit is known concerning the DNA sequences involved in the attachment. However, the function of this highly organized structure remains largely unknown.
J S, Zlatanova, K E, van Holde
openaire   +1 more source

Chromatin loops stack up

Nature Reviews Genetics, 2023
openaire   +2 more sources

Transcription shapes 3D chromatin organization by interacting with loop extrusion

Proceedings of the National Academy of Sciences of the United States of America, 2023
Edward Banigan, Hugo Brandao, Leonid A Mirny   +2 more
exaly  

Theory of chromatin organization maintained by active loop extrusion

Proceedings of the National Academy of Sciences of the United States of America, 2023
Michael Rubinstein, Brian Chan
exaly  

A comprehensive review of bioinformatics tools for chromatin loop calling

Briefings in Bioinformatics, 2023
Hao Lin, , Dong Gao
exaly  

TDRD3 promotes DHX9 chromatin recruitment and R-loop resolution

Nucleic Acids Research, 2021
Yanzhong Yang, Xiwei Wu, Hyejin Cho
exaly  

Entropic Competition between Supercoiled and Torsionally Relaxed Chromatin Fibers Drives Loop Extrusion through Pseudo-Topologically Bound Cohesin

Biology, 2021
Dusan Racko, Renata Ruskova, Racko Dusan   +2 more
exaly