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Analysis of Chromatin Interaction and Accessibility by Trac-Looping

2023
Spatial organization of the genome modulates pivotal biological processes. The emerging new technologies have provided novel insights into genome structure and its role in regulating cell activities. To examine the genome-wide chromatin interactions at accessible chromatin regions, we developed a DNA transposase-mediated analysis of chromatin looping ...
Shuai, Liu, Qingsong, Tang, Keji, Zhao
openaire   +2 more sources

BIOLOGICAL CONSEQUENCES OF CHROMATIN LOOPING IN PERICENTRIC CHROMATIN

2018
During mitosis, replicated sister chromatids are attached to opposite sides of a microtubule spindle at their centromeres in a process called biorientation. The proteinaceous structure that links centromeres, a region of the chromosome, to the spindle is called the kinetochore.
openaire   +1 more source

Chromatin loops and transcriptional regulation.

Critical reviews in eukaryotic gene expression, 1992
The existence of a supermolecular structure in the eukaryotic nucleus, involving loops of chromatin attached at irregularly spaced points to the nuclear matrix, is now well established. Quite a bit is known concerning the DNA sequences involved in the attachment. However, the function of this highly organized structure remains largely unknown.
J S, Zlatanova, K E, van Holde
openaire   +1 more source

Putting numbers on chromatin looping

Nature Structural & Molecular Biology
Adrian Henggeler, Fena Ochs
openaire   +2 more sources

Landscape of Cohesin-Mediated Chromatin Loops in the Human Genome

Nature, 2020
Marlene Rabinovitch   +2 more
exaly  

SnapHiC: A Computational Pipeline to Identify Chromatin Loops From Single-Cell Hi-C Data

Nature Methods, 2021
Guoqiang Li, Yuchen Yang, Yanxiao Zhang
exaly  

Transcription Shapes 3D Chromatin Organization by Interacting With Loop Extrusion

Proceedings of the National Academy of Sciences of the United States of America, 2023
Edward J Banigan   +2 more
exaly  

R Loops Regulate Chromatin Remodelling

Nature Reviews Molecular Cell Biology, 2015
Paulina Strzyz
exaly  

Human Cohesin Extrudes Interphase DNA to Make Loops

Nature Reviews Molecular Cell Biology, 2020
Kim Baumann
exaly  

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