Results 1 to 10 of about 182,469 (300)

Interaction of the Chromatin Remodeling Protein hINO80 with DNA. [PDF]

open access: yesPLoS ONE, 2016
The presence of a highly conserved DNA binding domain in INO80 subfamily predicted that INO80 directly interacts with DNA and we demonstrated its DNA binding activity in vitro.
Shweta Mendiratta   +4 more
doaj   +6 more sources

Chromatin remodeling protein BPTF mediates chromatin accessibility at gene promoters in planarian stem cells [PDF]

open access: yesBMC Genomics
Background The regulation of chromatin accessibility is essential in eukaryotic cells as one of several mechanisms that ensure gene activation occurs at appropriate times and in appropriate cell types.
Prince Verma   +3 more
doaj   +4 more sources

Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. [PDF]

open access: yesOncogenesis, 2020
Retinoblastoma is an aggressive childhood cancer of the developing retina that initiates by biallelic RB1 gene inactivation. Tumor progression in retinoblastoma is driven by epigenetics, as retinoblastoma genomes are stable, but the mechanism(s) that ...
Zocchi L   +8 more
europepmc   +8 more sources

CLOCK and TIMELESS regulate rhythmic occupancy of the BRAHMA chromatin-remodeling protein at clock gene promoters. [PDF]

open access: yesPLoS Genetics, 2023
Circadian clock and chromatin-remodeling complexes are tightly intertwined systems that regulate rhythmic gene expression. The circadian clock promotes rhythmic expression, timely recruitment, and/or activation of chromatin remodelers, while chromatin ...
Christine A Tabuloc   +5 more
doaj   +2 more sources

Chromatin Remodeling Protein ZmCHB101 Regulates Nitrate-Responsive Gene Expression in Maize [PDF]

open access: yesFrontiers in Plant Science, 2020
Nitrate is the main source of nitrogen for plants and an essential component of fertilizers. Rapid transcriptional activation of genes encoding the high-affinity nitrate transport system (HATS) is an important strategy that plants use to cope with ...
Xinchao Meng   +10 more
doaj   +2 more sources

Small molecule modulators of chromatin remodeling: from neurodevelopment to neurodegeneration

open access: yesCell & Bioscience, 2023
The dynamic changes in chromatin conformation alter the organization and structure of the genome and further regulate gene transcription. Basically, the chromatin structure is controlled by reversible, enzyme-catalyzed covalent modifications to chromatin
Dongfang Jiang   +4 more
doaj   +1 more source

Chromatin remodeler Activity-Dependent Neuroprotective Protein (ADNP) contributes to syndromic autism

open access: yesClinical Epigenetics, 2023
Background Individuals affected with autism often suffer additional co-morbidities such as intellectual disability. The genes contributing to autism cluster on a relatively limited number of cellular pathways, including chromatin remodeling.
Claudio Peter D’Incal   +10 more
doaj   +1 more source

De novo variants in GATAD2A in individuals with a neurodevelopmental disorder: GATAD2A-related neurodevelopmental disorder

open access: yesHGG Advances, 2023
Summary: GATA zinc finger domain containing 2A (GATAD2A) is a subunit of the nucleosome remodeling and deacetylase (NuRD) complex. NuRD is known to regulate gene expression during neural development and other processes.
Elizabeth A. Werren   +18 more
doaj   +1 more source

Akirin links twist-regulated transcription with the Brahma chromatin remodeling complex during embryogenesis. [PDF]

open access: yesPLoS Genetics, 2012
The activities of developmentally critical transcription factors are regulated via interactions with cofactors. Such interactions influence transcription factor activity either directly through protein-protein interactions or indirectly by altering the ...
Scott J Nowak   +4 more
doaj   +1 more source

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