The Role of RING Finger Proteins in Chromatin Remodeling and Biological Functions
Epigenomics, 2023 Mammalian DNA duplexes are highly condensed with different components, including histones, enabling chromatin formation. Chromatin remodeling is involved in multiple biological processes, including gene transcription regulation and DNA damage repair.
Xiaoxue Chai, Qian Tao, Lili Li
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Dynamic changes in ANGUSTIFOLIA3 complex composition reveal a growth regulatory mechanism in the maize leaf [PDF]
, 2015 Most molecular processes during plant development occur with a particular spatio-temporal specificity. Thus far, it has remained technically challenging to capture dynamic protein-protein interactions within a growing organ, where the interplay between ...
Aesaert, Stijn +17 more
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Chromatin remodeling and the circadian clock [PDF]
Plant Signaling & Behavior, 2011 Circadian rhythms are a universal way for organisms, ranging from prokaryotes to humans, to maintain coordination with the daily changes of light and temperature. It is known that a functional circadian clock confers enhanced fitness. In both animals and plants, diverse physiological processes are affected by the clock and more than 10% of transcripts ...
Sheen X, Lu, Elaine M, Tobin
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The true story of Yeti, the "abominable" heterochromatic gene of drosophila melanogaster [PDF]
, 2019 The Drosophila Yeti gene (CG40218) was originally identified by recessive lethal mutation and subsequently mapped to the deep pericentromeric heterochromatin of chromosome 2. Functional studies have shown that Yeti encodes a 241 amino acid protein called
Cuticone, Stefano +5 more
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Artificially Recruited TATA-Binding Protein Fails To Remodel Chromatin and Does Not Activate Three Promoters That Require Chromatin Remodeling [PDF]
Molecular and Cellular Biology, 2000 Transcriptional activators are believed to work in part by recruiting general transcription factors, such as TATA-binding protein (TBP) and the RNA polymerase II holoenzyme. Activation domains also contribute to remodeling of chromatin in vivo. To determine whether these two activities represent distinct functions of activation domains, we have ...
M P, Ryan +3 more
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SWI/SNF Infobase-An exclusive information portal for SWI/SNF remodeling complex subunits. [PDF]
PLoS ONE, 2017 Chromatin remodeling complexes facilitate the access of condensed genomic DNA during transcription, replication, and repair, by altering the histone-DNA contacts in the nucleosome structures.
Udayakumar Mani +3 more
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Chromatin Remodeling Proteins Interact with Pericentrin to Regulate Centrosome Integrity [PDF]
Molecular Biology of the Cell, 2007 Pericentrin is an integral centrosomal component that anchors regulatory and structural molecules to centrosomes. In a yeast two-hybrid screen with pericentrin we identified chromodomain helicase DNA-binding protein 4 (CHD4/Mi2β). CHD4 is part of the multiprotein nucleosome remodeling deacetylase (NuRD) complex.
Sillibourne, James +4 more
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The human Cranio Facial Development Protein 1 (Cfdp1) gene encodes a protein required for the maintenance of higher-order chromatin organization [PDF]
, 2017 The human Cranio Facial Development Protein 1 (Cfdp1) gene maps to chromosome 16q22.2-q22.3 and encodes the CFDP1 protein, which belongs to the evolutionarily conserved Bucentaur (BCNT) family.
Atterrato, Maria Teresa +5 more
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Conformational Change in the Chromatin Remodelling Protein MENT
PLoS ONE, 2009 Chromatin condensation to heterochromatin is a mechanism essential for widespread suppression of gene transcription, and the means by which a chromatin-associated protein, MENT, induces a terminally differentiated state in cells. MENT, a protease inhibitor of the serpin superfamily, is able to undergo conformational change in order to effect enzyme ...
Poh Chee Ong +11 more
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DNA repair synthesis and histone deposition partner during homologous recombination
Molecular & Cellular Oncology, 2018 Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and ...
Amira Elbakry +3 more
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