DNA methylation affects gene expression but not global chromatin structure in <i>Escherichia coli</i>. [PDF]
Morgan WJ, Amemiya HM, Freddolino L.
europepmc +1 more source
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He +9 more
wiley +1 more source
Dysregulation of histone methylation in SV40 chromosomes during replication results in aberrant transcription and chromatin structure. [PDF]
Milavetz B, Dawlaty R, Haugen J.
europepmc +1 more source
UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma +14 more
wiley +1 more source
AHDC1/Gibbin: a master regular of chromatin structure and gene transcription. [PDF]
Li L, Zhang C, Qin Y.
europepmc +1 more source
Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang +14 more
wiley +1 more source
The shifting paradigm of chromatin structure: from the 30-nm chromatin fiber to liquid-like organization. [PDF]
Maeshima K.
europepmc +1 more source
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu +9 more
wiley +1 more source
SRRM2 splicing factor modulates cell fate in early development
Silvia Carvalho +10 more
doaj +1 more source
The Impact of Polycomb Group Proteins on 3D Chromatin Structure and Environmental Stresses in Plants. [PDF]
Liu Y, Xiao S, Yang M, Guo G, Zhou Y.
europepmc +1 more source

