Results 291 to 300 of about 21,822,555 (337)
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Supranucleosomal structure of chromatin
Cell Biology International Reports, 1978Rat liver chromatin was moderately digested by micrococcal nuclease and analysed by centrifugation in isokinetic sucrose gradients and electron microscopy. Two classes of particles sedimenting with about 33S and 60S were characterized. Kinetics of their appearance and disappearance during progressive digestion suggests that they represent monomers and ...
W H, Strätling, U, Müller, H, Zentgraf
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Annual Review of Biochemistry, 1977
STRUCTURE OF NUCLEOSOMES 940 Core and Linker 940 Arrangement of Histones 942 Path Followed by the DNA 944 Conformation of Histones ...
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STRUCTURE OF NUCLEOSOMES 940 Core and Linker 940 Arrangement of Histones 942 Path Followed by the DNA 944 Conformation of Histones ...
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Chromatin structure in dementia
Annals of Neurology, 1984AbstractNuclei extracted from neocortex of patients with Alzheimer's disease and treated with micrococcal nuclease release a population of dinucleosomes that contain an increase in the linker histones H1° and H1ºº. Five other degenerative brain diseases that clinically resemble Alzheimer's disease do not result in these changes, although Pick's disease
D R, McLachlan +5 more
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Chromatin structure and epigenetics
Biochemical Pharmacology, 2006In eukaryotic cells, the DNA molecule is found in the form of a nucleoprotein complex named chromatin. The basic unit of the chromatin is the nucleosome, which comprises 147 base pairs of DNA wrapped around an octamer of core histones (made of two molecules of each H2A, H2B, H3, and H4 histones).
A S, Quina, M, Buschbeck, L, Di Croce
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Subunit structure of chromatin
Nature, 1974IN the past, the structure of chromatin has remained obscure despite the efforts of many laboratories and seemed far from a simple solution1. It has been known only that chromatin contains a repeating substructure2,3. Recently, however, Kornberg proposed4 that chromatin structure is based on a repeating subunit of 200 base pairs of DNA and two of each ...
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Critical Reviews in Eukaryotic Gene Expression, 1999
Independently of the enormous progress in our understanding of the structure of the core particle, there remain a multitude of structural questions still to be answered. The main points discussed here can be summarized as follows: (1) The meaning of the term 'core particle' should be widened to reflect the fact that the actual length of DNA wrapped ...
J, Zlatanova, S H, Leuba, K, van Holde
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Independently of the enormous progress in our understanding of the structure of the core particle, there remain a multitude of structural questions still to be answered. The main points discussed here can be summarized as follows: (1) The meaning of the term 'core particle' should be widened to reflect the fact that the actual length of DNA wrapped ...
J, Zlatanova, S H, Leuba, K, van Holde
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Structure of Replicating Chromatin
1996Publisher Summary This chapter summarizes the structural changes occurring in chromatin as replication-dependent events. The large genome of a eukaryotic cell is organized in the nucleus as a complex nucleoprotein structure, chromatin. The most dramatic changes in chromatin structure occur during genome replication, when advancing replication forks ...
C, Gruss, R, Knippers
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Structure of adenovirus chromatin
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1982The structure of adenovirus type 2 chromatin isolated from wild-type and ts1 virions was investigated by micrococcal nuclease digestion and electron microscopy. Partial digestion of wild-type and ts1 chromatin with micrococcal nuclease generated a multimeric DNA smear devoid of the 200 basepair nucleosome repeating pattern characteristic of cellular ...
M A, Mirza, J, Weber
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Structure of Transcribing Chromatin
1980Publisher Summary This chapter discusses the recent studies in order to draw a contemporary picture of the structure of transcribing chromatin. The basic structure of “active” chromatin, unique, repeating, altered nucleosomal structure, is discussed in this chapter.
D, Mathis, P, Oudet, P, Chambon
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STRUCTURE AND FUNCTION OF CHROMATIN
Annual Review of Genetics, 1979Shape of the Core Particle . Conformation of DNA in the Core Particle . The Organization of Histones in the Core Particle . The Nucleosome as a Dynamic Structure . ORGANIZATION OF THE CHROMATIN THREAD . Separation Between Subunits . Orientation of Units in the Chromatin Unit Thread . Higher Order Structures . TRANSCRIPTION OF CHROMATIN
D M, Lilley, J F, Pardon
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