Results 271 to 280 of about 272,086 (309)
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Structure of Chromatin in Spermatozoa
2013The specialized structure of the sperm chromatin has a dual function - first to protect the DNA from damage during storage and transport to the oocyte, and then to enable a rapid and complete unpacking of the undamaged paternal genome in the ooplasm. It is evident that zinc has a pivotal role in maintaining the structural stability and in enabling a ...
Lars, Björndahl, Ulrik, Kvist
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Critical Reviews in Eukaryotic Gene Expression, 1999
Independently of the enormous progress in our understanding of the structure of the core particle, there remain a multitude of structural questions still to be answered. The main points discussed here can be summarized as follows: (1) The meaning of the term 'core particle' should be widened to reflect the fact that the actual length of DNA wrapped ...
J, Zlatanova, S H, Leuba, K, van Holde
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Independently of the enormous progress in our understanding of the structure of the core particle, there remain a multitude of structural questions still to be answered. The main points discussed here can be summarized as follows: (1) The meaning of the term 'core particle' should be widened to reflect the fact that the actual length of DNA wrapped ...
J, Zlatanova, S H, Leuba, K, van Holde
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Structure of adenovirus chromatin
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1982The structure of adenovirus type 2 chromatin isolated from wild-type and ts1 virions was investigated by micrococcal nuclease digestion and electron microscopy. Partial digestion of wild-type and ts1 chromatin with micrococcal nuclease generated a multimeric DNA smear devoid of the 200 basepair nucleosome repeating pattern characteristic of cellular ...
M A, Mirza, J, Weber
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Subunit structure of chromatin
Nature, 1974IN the past, the structure of chromatin has remained obscure despite the efforts of many laboratories and seemed far from a simple solution1. It has been known only that chromatin contains a repeating substructure2,3. Recently, however, Kornberg proposed4 that chromatin structure is based on a repeating subunit of 200 base pairs of DNA and two of each ...
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Cell Biology International Reports, 1978
Active gene sequences are present in the nucleosomal fraction of chromatin. Histones are attached to the DNA of transcribing non-ribosomal genes, and EM images suggest that their conformation is related to that of nucleosomes, or is readily converted to that structure on preparation for microscopy.
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Active gene sequences are present in the nucleosomal fraction of chromatin. Histones are attached to the DNA of transcribing non-ribosomal genes, and EM images suggest that their conformation is related to that of nucleosomes, or is readily converted to that structure on preparation for microscopy.
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The Structure and Function of Chromatin
1972Biochemical and genetic studies have produced a vast fund of knowledge concerning gene action and regulation in prokaryotes. In these organisms the DNA is exposed rather nakedly to the world, protected primarily by the cell membrane. In eukaryotes the DNA seems far better shielded, being enmeshed in histone and nonhistone proteins and sequestered ...
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Proceedings, annual meeting, Electron Microscopy Society of America, 1970
Chromatin from calf thymus has been reinvestigated.If the extraction procedure of Zubay and Doty is altered through the omission of EDTA and the resulting fibrils are picked up on grids by the method of Koller et al from a solution containing no added salt, one observes fibrils of diameter about 230 Å. (Figure A). This is the same diameter as was found
Janice L. Jones, Michael Beer
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Chromatin from calf thymus has been reinvestigated.If the extraction procedure of Zubay and Doty is altered through the omission of EDTA and the resulting fibrils are picked up on grids by the method of Koller et al from a solution containing no added salt, one observes fibrils of diameter about 230 Å. (Figure A). This is the same diameter as was found
Janice L. Jones, Michael Beer
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2018
Chromatin is the physical representative of the epigenome. Histones are the main protein component of chromatin and form octamer cores, around which genomic DNA is wrapped. These nucleosomes are the regularly repeating units of chromatin, but they can vary from one genomic region to the other by (i) different post-translational modifications of amino ...
Carsten Carlberg, Ferdinand Molnár
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Chromatin is the physical representative of the epigenome. Histones are the main protein component of chromatin and form octamer cores, around which genomic DNA is wrapped. These nucleosomes are the regularly repeating units of chromatin, but they can vary from one genomic region to the other by (i) different post-translational modifications of amino ...
Carsten Carlberg, Ferdinand Molnár
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Chromatin Structure and Transcription
Annual Review of Cell Biology, 1992R D, Kornberg, Y, Lorch
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