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The structure and function of chromatin
, 1975 Symposium on the Structure and Function of Chromatin <1974, London, England>
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Nature New Biology, 1971
Physico-chemical experiments show that histones are not evenly distributed in chromatin. About half of the DNA is “open” and not covered with proteins.
R J, Clark, G, Felsenfeld
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Physico-chemical experiments show that histones are not evenly distributed in chromatin. About half of the DNA is “open” and not covered with proteins.
R J, Clark, G, Felsenfeld
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Chromatin structure in dementia
Annals of Neurology, 1984AbstractNuclei extracted from neocortex of patients with Alzheimer's disease and treated with micrococcal nuclease release a population of dinucleosomes that contain an increase in the linker histones H1° and H1ºº. Five other degenerative brain diseases that clinically resemble Alzheimer's disease do not result in these changes, although Pick's disease
D R, McLachlan +5 more
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Annual Review of Biochemistry, 1977
STRUCTURE OF NUCLEOSOMES 940 Core and Linker 940 Arrangement of Histones 942 Path Followed by the DNA 944 Conformation of Histones ...
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STRUCTURE OF NUCLEOSOMES 940 Core and Linker 940 Arrangement of Histones 942 Path Followed by the DNA 944 Conformation of Histones ...
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Chromatin structure and epigenetics
Biochemical Pharmacology, 2006In eukaryotic cells, the DNA molecule is found in the form of a nucleoprotein complex named chromatin. The basic unit of the chromatin is the nucleosome, which comprises 147 base pairs of DNA wrapped around an octamer of core histones (made of two molecules of each H2A, H2B, H3, and H4 histones).
A S, Quina, M, Buschbeck, L, Di Croce
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Structure of Replicating Chromatin
1996Publisher Summary This chapter summarizes the structural changes occurring in chromatin as replication-dependent events. The large genome of a eukaryotic cell is organized in the nucleus as a complex nucleoprotein structure, chromatin. The most dramatic changes in chromatin structure occur during genome replication, when advancing replication forks ...
C, Gruss, R, Knippers
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Structure of Transcribing Chromatin
1980Publisher Summary This chapter discusses the recent studies in order to draw a contemporary picture of the structure of transcribing chromatin. The basic structure of “active” chromatin, unique, repeating, altered nucleosomal structure, is discussed in this chapter.
D, Mathis, P, Oudet, P, Chambon
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STRUCTURE AND FUNCTION OF CHROMATIN
Annual Review of Genetics, 1979Shape of the Core Particle . Conformation of DNA in the Core Particle . The Organization of Histones in the Core Particle . The Nucleosome as a Dynamic Structure . ORGANIZATION OF THE CHROMATIN THREAD . Separation Between Subunits . Orientation of Units in the Chromatin Unit Thread . Higher Order Structures . TRANSCRIPTION OF CHROMATIN
D M, Lilley, J F, Pardon
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THE STRUCTURE OF EUKARYOTE CHROMATIN
Acta Endocrinologica, 1972ABSTRACT In this paper certain aspects of the structure of chromatin are considered, with emphasis on the relationships of histone and residual protein to DNA. Recent findings relative to the complexing of histone with DNA are reviewed and material from this laboratory concerning the ratio of total histone to DNA and related topics are ...
A L, Dounce +5 more
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Supranucleosomal structure of chromatin
Cell Biology International Reports, 1978Rat liver chromatin was moderately digested by micrococcal nuclease and analysed by centrifugation in isokinetic sucrose gradients and electron microscopy. Two classes of particles sedimenting with about 33S and 60S were characterized. Kinetics of their appearance and disappearance during progressive digestion suggests that they represent monomers and ...
W H, Strätling, U, Müller, H, Zentgraf
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