Results 61 to 70 of about 432,155 (258)

A Systematic Review of the Protective Actions of Cat’s Whiskers (Misai Kucing) on the Central Nervous System

Frontiers in Pharmacology, 2020
Orthosiphon stamineus (OS) or Orthosiphon aristatus var. aristatus (OAA) is commonly known as cat’s whiskers or “misai kucing”. It is an herbaceous shrub that is popular in many different traditional and complementary medicinal systems.
Yin-Sir Chung, Yin-Sir Chung, Brandon Kar Meng Choo, Pervaiz Khalid Ahmed, Pervaiz Khalid Ahmed, Iekhsan Othman, Iekhsan Othman, Mohd. Farooq Shaikh   +7 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Clinical laboratory use of liquid chromatography mass spectrometry

Türk Biyokimya Dergisi, 2022
Mass spectrometric methods, which transition from chemistry laboratories to clinical laboratories in the basic field, are frequently used in areas such as metabolic analysis, endocrinology, drug research, protein studies and toxicology.
Unlu Ali, Abusoglu Sedat
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Liquid Chromatography/Mass Spectrometry

, 2012
In this article, selected examples of applications of liquid chromatography coupled to mass spectrometry are given. The examples include the analysis of i) impurities in manufactured, pharmaceutical or synthesis products, ii) polyphenols in natural products, and iii) phytohormones in plant extracts.
Jáuregui Pallarés, Olga, Casals i Ribes, Isidre, Fernández Vidal, Irene   +2 more
openaire   +3 more sources

A VAMS‐based LC–MS/MS method for precise cenobamate quantification in epilepsy (patients)

Epilepsia Open
Objective Cenobamate (CNB), a recently approved antiseizure medication by the European Medicines Agency (EMA), serves as an adjunctive therapy for focal‐onset seizures in adult patients unresponsive to at least two other treatments.
Federica Pigliasco, Alessia Cafaro, Sebastiano Barco, Margherita Biondi, Manuela Stella, Francesca Mattioli, Antonella Riva, Ugo deGrazia, Linda Molteni, Elisa Micalizzi, Flavio Villani, Pasquale Striano, Roberto Bandettini, Giuliana Cangemi   +13 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Focal Point: Hyphenated Mass Spectrometry: A. Liquid Chromatography – Mass Spectrometry

CHIMIA, 2003
The identification of unknown compounds is essential in a wide variety of research areas and especially so in environmental analysis. Combining liquid chromatography with tandem mass spectrometry today allows the identification of substances ...
W. Giger
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Mass Spectrometric Fingerprinting to Detect Fraud and Herbal Adulteration in Plant Food Supplements

Molecules
Mass spectrometric (MS) fingerprinting coupled with chemometrics for the detection of plants in plant mixtures is sparsely researched. This paper aims to check its value for herbal adulteration concerning plants with slimming as an indication.
Surbhi Ranjan, Tanika Van Mulders, Koen De Cremer, Erwin Adams, Eric Deconinck   +4 more
doaj   +1 more source