Gas Chromatography-Mass Spectrometry [PDF]
, 1971 In choosing a method by which to identify drug metabolites, the quantity of material which is available is a prime consideration. In this regard, pharmacologists find themselves midway between natural products chemists and biochemists. Usually the former has reasonably large quantities of material available in a relatively high state of purity.
A. M. Guarino, H. M. Fales
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Analyzing peptides and proteins by mass spectrometry: principles and applications in proteomics [PDF]
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166The study of proteins has been a key element in biomedicine and biotechnology because of their important role in cell functions or enzymatic activity. Cells are the basic unit of living
Estanyol i Ullate, Josep Maria +3 more
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Determination of Pharmaceuticals in Coastal Systems Using Solid Phase Extraction (SPE) Followed by Ultra Performance Liquid Chromatography – tandem Mass Spectrometry (UPLC-MS/MS) [PDF]
, 2015 This paper describes the optimization and validation of an analytical method for the determination of 83 pharmaceutically active compounds (PhACs) in aqueous samples using solid-phase extraction (SPE) followed by ultra performance liquid chromatography ...
Baena Nogueras, Rosa María +3 more
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Frontiers in Psychiatry, 2018 This is the first study to identify lipidomic markers in plasma associated with response of acutely ill schizophrenia patients in response to specific antipsychotic treatments.
Adriano Aquino +10 more
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The use of high performance anion exchange chromatography for the detection of counterfeit pharmaceutical products using the excipient content as a marker [PDF]
, 2015 The aim of the investigation described here was to examine the differences between genuine and counterfeit pharmaceutical products through the development of an analytical method capable of rigorously identifying the sugar-based excipients.
Beasley, Emma +2 more
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Optimized Analytical Procedures for the Untargeted Metabolomic Profiling of Human Urine and Plasma by Combining Hydrophilic Interaction (HILIC) and Reverse-Phase Liquid Chromatography (RPLC)-Mass Spectrometry. [PDF]
, 2015 Profiling of body fluids is crucial for monitoring and discovering metabolic markers of health and disease and for providing insights into human physiology.
Contrepois, Kévin +2 more
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Analytical characterization of some synthetic cannabinoids, derivatives of indole-3-carboxylic acid [PDF]
, 2013 By means of gas chromatography with high resolution mass spectrometry (GC-HRMS), ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry (UHPLC-HRMS), nuclear magnetic resonance spectroscopy (NMR) and ...
Eltsov, O. +4 more
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, 2013 The objectives of the review are the collection, concise description and evaluation of the various chromatographic technologies applied for the separation and quantitative determination of macro- and microcomponents present in ...
Cserháti, Tibor, Szőgyi, Mária
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Multianalyte LC-MS-based methods in doping control: what are the implications for doping athletes? [PDF]
, 2016 Over the last 50 years, the list of doping substances and methods has been progressively expanding, being regularly reviewed by the international antidoping authorities (formerly the Medical Commission of the International Olympic Committee, and ...
Botre', Francesco +2 more
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Quantification of growth hormone in serum by isotope dilution mass spectrometry [PDF]
, 2009 Inter-assay variation of antibody based routine tests is hampering comparability of measurement results for growth hormone (GH) between different laboratories and decision making in clinical practice. Here it is demonstrated, that quantification of GH by
André +4 more
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