Results 31 to 40 of about 3,141,961 (402)

Recent Trends in Graphene-Based Sorbents for LC Analysis of Food and Environmental Water Samples

open access: yesMolecules, 2023
This review provides an overview of recent advancements in applying graphene-based materials as sorbents for liquid chromatography (LC) analysis. Graphene-based materials are promising for analytical chemistry, including applications as sorbents in ...
João V. B. Borsatto   +1 more
doaj   +1 more source

Recent Developments in Two-Dimensional Liquid Chromatography: Fundamental Improvements for Practical Applications

open access: yesAnalytical Chemistry, 2018
Liquid chromatography (LC) is an incredibly successful analytical separation tool. Its versatility is unprecedented, because of the many different separation modes (reversed-phase LC, ion-exchange chromatography, size-exclusion chromatography, etc.) and ...
Bob W. J. Pirok   +2 more
semanticscholar   +1 more source

Efficiency of a solvatic sorption model for the prediction of retention times in linear gradient reversed-phase liquid chromatography working with different stationary phases; pp. 37–49 [PDF]

open access: yesProceedings of the Estonian Academy of Sciences, 2016
Currently several different approaches are used for speed-up and cost reduction for new method development in reversed-phase high-performance liquid chromatography.
Svetlana Vorslova   +3 more
doaj   +1 more source

A UHPLC–MS/MS Method for Therapeutic Drug Monitoring of Aciclovir and Ganciclovir in Plasma and Dried Plasma Spots

open access: yesBiomedicines, 2021
The role of therapeutic drug monitoring (TDM) of valaciclovir (VA)/aciclovir (A) and valganciclovir/ganciclovir (VG/G) in critically ill patients is still a matter of debate.
Federica Pigliasco   +8 more
doaj   +1 more source

A Novel LC–MS/MS-Based Method for the Diagnosis of ADA2 Deficiency from Dried Plasma Spot

open access: yesMolecules, 2021
Adenosine Deaminase 2 Deficiency (DADA2) (OMIM: 607575) is a monogenic, autoinflammatory disease caused by the loss of functional homozygous or heterozygous mutations in the ADA 2 gene (previously CECR1, Cat Eye Syndrome Chromosome Region 1).
Alessia Cafaro   +9 more
doaj   +1 more source

Gel filtration chromatography [PDF]

open access: yes, 2011
Gel-filtration chromatography is a popular and versatile technique that permits the effective separation of proteins and other biological molecules in high yield. Here, the basis of the method is described and typical matrix types are contrasted.
Cummins, Phil   +2 more
core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Chromatography of beer [PDF]

open access: yes, 2013
The objectives of the review are the collection, concise description and evaluation of the various chromatographic techniques used for the separation and quantitative determination of macro- and microcomponents present in ...
Cserháti, Tibor, Szőgyi, Mária
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Immobilization of cytochrome P450 enzymes onto magnetic beads: An approach to drug metabolism and biocatalysis

open access: yesTalanta Open, 2023
Cytochrome P450 (CYP, P450) presents a wide range of applicability in drug metabolism studies and in biocatalysis as a great alternative to synthesizing compounds. Nonetheless, their lack of stability is one of their major drawbacks.
Izadora Liranço Furlani   +2 more
doaj   +1 more source

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