Results 71 to 80 of about 6,135 (207)

Cytogenetics and cytotaxonomy of some Brazilian species of Cymbidioid orchids

open access: yesGenetics and Molecular Biology, 2000
The Cymbidioid phylad presents the widest chromosome number variation among orchids, with records varying from 2n = 10 in Psygmorchis pusilla to 2n = 168 in two species of Oncidium.
Leonardo Pessoa Félix, Marcelo Guerra
doaj   +1 more source

ATRX: From Chromatin Remodeling to Disease

open access: yesgenesis, Volume 63, Issue 6, December 2025.
ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta   +1 more
wiley   +1 more source

Establishment and Characterization of Bovine Trophoblast Stem Cells Growing as Adherent Cells or Vesicles

open access: yesMolecular Reproduction and Development, Volume 92, Issue 12, December 2025.
ABSTRACT In ungulates, the development of the trophoblast lineage follows a peculiar process, as implantation is preceded by a relatively long period of trophoblast elongation, the molecular control of which is still not well known. Here, we have established novel bovine trophoblast stem cells (b2iTSCs) growing in a completely defined medium containing
Camille Baquerre   +9 more
wiley   +1 more source

Aggregation of the Constitutively Active K296E Rhodopsin Mutant Contributes to Retinal Degeneration

open access: yesThe FASEB Journal, Volume 39, Issue 14, 31 July 2025.
The K296E rhodopsin mutation causes autosomal dominant retinitis pigmentosa. The pathogenic effect of the mutation has typically been attributed to effects related to the constitutive activity detected in the mutant in some studies. We demonstrate here that the K296E rhodopsin mutant aggregates.
Sreelakshmi Vasudevan   +2 more
wiley   +1 more source

Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang   +4 more
wiley   +1 more source

Distribution of the retrotransposable element 412 in Drosophila species [PDF]

open access: yes, 1998
Copy numbers of sequences homologous to the Drosophila melanogaster retrotransposable element 412, their dis tribution between the chromosome arms and the chromocenter, and whether they contain full-size copies were analyzed for 55 species of the ...
Biemont, C.   +4 more
core   +1 more source

Chromatin Topological Domains Associate With the Rapid Formation of Tandem Duplicates in Plants

open access: yesAdvanced Science, Volume 12, Issue 7, February 17, 2025.
A collection of Hi‐C matrices across the plant kingdom confirms the interrelation between large‐scale chromosome conformation and species genome size. At a finer level, tandem duplicate gene clusters preferentially fold into topologically associating domains (TADs) in an evolutionarily conserved manner.
Ni Ma   +9 more
wiley   +1 more source

Nuclear mechanostability emerges from satellite DNA condensation into chromocenters

open access: yes
ABSTRACT As the largest organelle, the nucleus endures significant mechanical stresses over the cellular lifespan, and mechanostability, i.e. the ability to resist deformation, is critical for genome integrity and function. Here, we reveal that nuclear mechanostability is an emergent property arising from the clustering of satellite DNA
Brändle FB   +14 more
europepmc   +2 more sources

Characterization of radiations‐induced genomic structural variations in Arabidopsis thaliana

open access: yesThe Plant Journal, Volume 121, Issue 1, January 2025.
Significance Statement Exposure to genotoxic stress activates DNA damage response (DDR) and challenges genome integrity. Using third generation sequencing technology, we characterized alterations of the linear genome structure of Arabidopsis plants treated with non‐ionizing (UV‐B, UV‐C) and ionizing radiations (protons). We identified, in wild type and
Salimata Ousmane Sall   +9 more
wiley   +1 more source

Centromeric regions of A. fraterculus polytene chromosomes.

open access: yes, 2016
(A) Centromeres of chromosomes II and III, (B) a partial chromocenter involving chromosomes III and V, (C) a partial chromocenter involving three chromosomes, II, III and V. Arrows indicate the heterochromatic threads in (A). C indicates the centromere.
Antigone Zacharopoulou (798908)   +9 more
core   +1 more source

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