Results 71 to 80 of about 6,135 (207)
Cytogenetics and cytotaxonomy of some Brazilian species of Cymbidioid orchids
The Cymbidioid phylad presents the widest chromosome number variation among orchids, with records varying from 2n = 10 in Psygmorchis pusilla to 2n = 168 in two species of Oncidium.
Leonardo Pessoa Félix, Marcelo Guerra
doaj +1 more source
ATRX: From Chromatin Remodeling to Disease
ABSTRACT Chromatin remodeling proteins are evolutionarily conserved factors involved in a wide range of biological processes. In this review, we describe ATRX, a chromatin remodeling protein belonging to the SWI/SNF2 family. Its association with different protein complexes, and its roles in embryonic development, sexual differentiation, as well as ...
Mauro Magaña‐Acosta +1 more
wiley +1 more source
ABSTRACT In ungulates, the development of the trophoblast lineage follows a peculiar process, as implantation is preceded by a relatively long period of trophoblast elongation, the molecular control of which is still not well known. Here, we have established novel bovine trophoblast stem cells (b2iTSCs) growing in a completely defined medium containing
Camille Baquerre +9 more
wiley +1 more source
Aggregation of the Constitutively Active K296E Rhodopsin Mutant Contributes to Retinal Degeneration
The K296E rhodopsin mutation causes autosomal dominant retinitis pigmentosa. The pathogenic effect of the mutation has typically been attributed to effects related to the constitutive activity detected in the mutant in some studies. We demonstrate here that the K296E rhodopsin mutant aggregates.
Sreelakshmi Vasudevan +2 more
wiley +1 more source
Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang +4 more
wiley +1 more source
Distribution of the retrotransposable element 412 in Drosophila species [PDF]
Copy numbers of sequences homologous to the Drosophila melanogaster retrotransposable element 412, their dis tribution between the chromosome arms and the chromocenter, and whether they contain full-size copies were analyzed for 55 species of the ...
Biemont, C. +4 more
core +1 more source
Chromatin Topological Domains Associate With the Rapid Formation of Tandem Duplicates in Plants
A collection of Hi‐C matrices across the plant kingdom confirms the interrelation between large‐scale chromosome conformation and species genome size. At a finer level, tandem duplicate gene clusters preferentially fold into topologically associating domains (TADs) in an evolutionarily conserved manner.
Ni Ma +9 more
wiley +1 more source
Nuclear mechanostability emerges from satellite DNA condensation into chromocenters
ABSTRACT As the largest organelle, the nucleus endures significant mechanical stresses over the cellular lifespan, and mechanostability, i.e. the ability to resist deformation, is critical for genome integrity and function. Here, we reveal that nuclear mechanostability is an emergent property arising from the clustering of satellite DNA
Brändle FB +14 more
europepmc +2 more sources
Characterization of radiations‐induced genomic structural variations in Arabidopsis thaliana
Significance Statement Exposure to genotoxic stress activates DNA damage response (DDR) and challenges genome integrity. Using third generation sequencing technology, we characterized alterations of the linear genome structure of Arabidopsis plants treated with non‐ionizing (UV‐B, UV‐C) and ionizing radiations (protons). We identified, in wild type and
Salimata Ousmane Sall +9 more
wiley +1 more source
Centromeric regions of A. fraterculus polytene chromosomes.
(A) Centromeres of chromosomes II and III, (B) a partial chromocenter involving chromosomes III and V, (C) a partial chromocenter involving three chromosomes, II, III and V. Arrows indicate the heterochromatic threads in (A). C indicates the centromere.
Antigone Zacharopoulou (798908) +9 more
core +1 more source

