Results 81 to 90 of about 5,729 (189)
The Plant Journal, Volume 119, Issue 3, Page 1418-1432, August 2024.SUMMARY DNA–protein crosslinks (DPCs) are highly toxic DNA lesions represented by proteins covalently bound to the DNA. Persisting DPCs interfere with fundamental genetic processes such as DNA replication and transcription. Cytidine analog zebularine (ZEB) has been shown to crosslink DNA METHYLTRANSFERASE1 (MET1). Recently, we uncovered a critical role
Eva Dvořák Tomaštíková +6 more
wiley +1 more source
New Phytologist, Volume 243, Issue 1, Page 213-228, July 2024.Summary Arabidopsis lamin analogs CROWDED NUCLEIs (CRWNs) are necessary to maintain nuclear structure, genome function, and proper plant growth. However, whether and how CRWNs impact reproduction and genome‐wide epigenetic modifications is unknown.
Junsik Choi, Mary Gehring
wiley +1 more source
Centromere diversity: How different repeat‐based holocentromeres may have evolved
BioEssays, Volume 46, Issue 6, June 2024.The conserved function of the centromere does not limit its structural diversity. Various mechanisms drive the evolution of structurally diverse holocentromeres across different lineages. The incorporation of centromeric DNA‐carrying extra‐chromosomal circular DNAs (eccDNAs) and transposable elements (TEs) might be involved in mono‐to‐holocentric ...
Yi‐Tzu Kuo +4 more
wiley +1 more source
A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation
Nucleic Acids Research, 2020 AbstractDuring interphase centromeres often coalesce into a small number of chromocenters, which can be visualized as distinct, DAPI dense nuclear domains. Intact chromocenters play a major role in maintaining genome stability as they stabilize the transcriptionally silent state of repetitive DNA while ensuring centromere function.
Axel Imhof +8 more
openaire +3 more sources
Nature CommunicationsPhotobodies (PBs) are membraneless subnuclear organelles that self-assemble via concentration-dependent liquid-liquid phase separation (LLPS) of the plant photoreceptor and thermosensor phytochrome B (PHYB).
Juan Du, Keunhwa Kim, Meng Chen
doaj +1 more source
The Polycomb group protein CRAMPED is involved with TRF2 in the activation of the histone H1 gene [PDF]
, 2018 CRAMPED (CRM), conserved from plants to animals, was previously characterized genetically as a repressive factor involved in the formation of facultative and constitutive heterochromatin (Polycomb silencing, position effect variegation). We show that crm
Gibert, Jean-Michel, Karch, François
core
Sumoylation of Drosophila SU(VAR)3-7 is required for its heterochromatic function [PDF]
, 2017 In Drosophila, SU(VAR)3-7 is an essential heterochromatin component. It is required for proper chromatin condensation, and changing its dose modifies position-effect variegation.
Bontron, Séverine +3 more
core
Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming [PDF]
, 2013 Previous studies have revealed that mouse primordial germ cells (PGCs) undergo genome-wide DNA methylation reprogramming to reset the epigenome for totipotency. However, the precise 5-methylcytosine (5mC) dynamics and its relationship with the generation
Hong, Kwonho +6 more
core +1 more source
A new cytotype of Anopheles nuneztovari from western Venezuela and Colombia. [PDF]
, 1993 Volume:
core
SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin. [PDF]
, 2011 International audienceHP1 enrichment at pericentric heterochromatin is considered important for centromere function. Although HP1 binding to H3K9me3 can explain its accumulation at pericentric heterochromatin, how it is initially targeted there remains ...
Almouzni, Geneviève +10 more
core +3 more sources