Results 71 to 80 of about 946 (139)

Supplementary Table S1-S5 from Chromoplexy Is a Frequent Early Clonal Event in <i>EWSR1</i>-Rearranged Round Cell Sarcomas That Can Be Detected Using Clinically Validated Targeted Sequencing Panels

<p>Supplementary Tables S1-S3. List of chromoplectic structural variants, including chromosomal coordinates, event type, and annotated genes/genomic regions, in cases with EWSR1::FLI1 (Table S1), EWSR1::ERG (Table S2), EWSR1::WT1 (Table S3) driver fusions, and longitudinal/sequencing samples from patients with EWSR1::FLI1 or EWSR1::WT1 driver ...
Cristina R. Antonescu, Chad M. Vanderbilt, Fabio Vanoli, John Healey, Leonard Wexler, Paul Meyers, William D. Tap, Emily Slotkin, Josephine K. Dermawan   +8 more
openaire   +1 more source

Patterns and mechanisms of structural variations in human cancer

Experimental and Molecular Medicine, 2018
Next-generation sequencing technology has enabled the comprehensive detection of genomic alterations in human somatic cells, including point mutations, chromosomal rearrangements, and structural variations (SVs).
Kijong Yi, Y. Ju
semanticscholar   +1 more source

Data from Chromoplexy Is a Frequent Early Clonal Event in <i>EWSR1</i>-Rearranged Round Cell Sarcomas That Can Be Detected Using Clinically Validated Targeted Sequencing Panels

<div>Abstract<p>Chromoplexy is a phenomenon defined by large-scale chromosomal chained rearrangements. A previous study observed chromoplectic events in a subset of Ewing sarcomas (ES), which was linked to an increased relapse rate. Chromoplexy analysis could potentially facilitate patient risk stratification, particularly if it could be ...
Cristina R. Antonescu, Chad M. Vanderbilt, Fabio Vanoli, John Healey, Leonard Wexler, Paul Meyers, William D. Tap, Emily Slotkin, Josephine K. Dermawan   +8 more
openaire   +1 more source

Supplementary Figures and Tables Legends from Chromoplexy Is a Frequent Early Clonal Event in <i>EWSR1</i>-Rearranged Round Cell Sarcomas That Can Be Detected Using Clinically Validated Targeted Sequencing Panels

<p>Supplementary Figures and Tables Legends</p>
Cristina R. Antonescu, Chad M. Vanderbilt, Fabio Vanoli, John Healey, Leonard Wexler, Paul Meyers, William D. Tap, Emily Slotkin, Josephine K. Dermawan   +8 more
openaire   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

High-resolution copy-number mutational signatures for ovarian cancer patient stratification

During tumour evolution, diverse mutational processes can affect copy number state across the genome, by deleting or duplicating sections of genomic material.
Mattocks, Joanne
core   +1 more source

Roles of somatic mutations in STAG2, TP53 and CDKN2A and chromoplexy in Ewing sarcoma oncogenesis

Le sarcome d'Ewing est le second cancer pédiatrique des os et tissus mous le plus fréquent. Il est caractérisé par la présence d'une translocation chromosomique fusionnant un gène de la famille FET à un facteur de transcription de la famille des ETS ...
Heintzé, Maxime
core  

Whole-genome sequencing of human malignant mesothelioma tumours and cell lines

, 2019
Pleural mesothelioma is a cancer of serosal surfaces caused by environmental exposure to asbestos. Clinical outcome remains poor and while trials of new treatments are ongoing it remains an understudied cancer.
Bowman, Rayleen V., Krause, Lutz, Chee, Tian Mun, Ellis, Jonathan J., Davidson, Morgan R., Yang, Ian A., Daniels, Marissa, Fong, Kwun M., Oey, Harald, Relan, Vandana   +9 more
core   +1 more source

Clinical impact of chromothriptic Complex Chromosomal Rearrangements in newly diagnosed multiple myeloma

, 2019
Complex Chromosomal Rearrangements (CCRs) are increasingly being reported as genetic risk factors of clinical significance in cancer owing to their identification using high resolution whole genome profiling technologies.
Rani, Lata, Mathur, Nitin, Singh, Vishwajeet, Gupta, Anubha, Gupta, Ritu, Sharma, Atul, Kaur, Gurvinder, Kumar, Lalit, Sharma, Om Dutt   +8 more
core   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source