Results 81 to 90 of about 35,640 (295)

Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test [PDF]

, 2012
The genotoxicity of quinolone and fluroquinolones was assessed using the micronucleus (MN) test on Viciafaba roots by direct contact exposure to a solid matrix.
Bousquet-Mélou, Alain, Guiresse, Agnès Maritchù, Hafidi, Mohamed, Hamdi, Hassan, Khadra, Ahmed, Lacroix, Marlene Z., Merlina, Georges, Pinelli, Eric   +7 more
core   +3 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Effect of linear energy transfer (LET) on complexity of alpha-particle-induced chromosome aberrations in human CD34+ cells. [PDF]

, 2007
The aim of this study was to assess the relative influence of linear energy transfer (LET) of α-particles on chromosome aberration complexity in the absence of significant other track structure differences.
Anderson, RM, Goodhead, DT, Hill, MA, Stevens, DL, Sumption, ND, Tounsend, KMS   +5 more
core  

Chromosomal radiosensitivity and acute radiation side effects after radiotherapy in tumour patients - a follow-up study [PDF]

, 2011
Radiotherapists are highly interested in optimizing doses especially for patients who tend to suffer from side effects of radiotherapy (RT). It seems to be helpful to identify radiosensitive individuals before RT.
Baumgartner, Adi, Braselmann, Herbert, Figel, Markus, Geinitz, Hans, Huber, Reinhard, Jaehnert, Irene, Molls, Michael, Thamm, Reinhard, Zitzelsberger, Horst   +8 more
core   +3 more sources

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Prenatal evaluation of a fetus with trisomy 18 and additional balanced de novo Rob(13;14).

Folia Histochemica et Cytobiologica, 2010
The main aim of this work is to present unusual case with full trisomy 18 and additional robertsonian translocation- Rob (13;14) detected through abnormalities found in prenatal ultrasound examination. A 26 years-old pregnant women with no family history
R Posmyk, R Leśniewicz, I Leśniewicz, S Wołczyński   +3 more
doaj   +1 more source

Gene Co-expression Network and Copy Number Variation Analyses Identify Transcription Factors Associated With Multiple Myeloma Progression [PDF]

, 2019
Multiple myeloma (MM) has two clinical precursor stages of disease: monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). However, the mechanism of progression is not well understood.
Abu Zaid, Mohammad, Han, Zhi, Huang, Kun, Huang, Zhi, Johnson, Travis S., Xiang, Shunian, Yu, Christina Y., Zhan, Xiaohui   +7 more
core   +5 more sources

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Physicochemical Quality and Genotoxic Potential of Wastewater Generated by Canteen Complex

ARO-The Scientific Journal of Koya University, 2019
Canteens generate high volumes of wastewater that should constantly be subjected to physicochemical and genotoxicity screening. In this study, the wastewater generated by a canteen complex was screened for physicochemical properties and genotoxic ...
Ebenezer O. Dada, Chioma M. Agu, Modupe O. Akinola   +2 more
doaj   +1 more source

Modelling radiation-induced cell cycle delays

, 2009
Ionizing radiation is known to delay the cell cycle progression. In particular after particle exposure significant delays have been observed and it has been shown that the extent of delay affects the expression of damage such as chromosome aberrations ...
AD Virgilio, Anna Ochab-Marcinek, B Basse, E Erba, E Gudowska-Nowak, Elena Nasonova, Ewa Gudowska-Nowak, F Montalenti, FA Cucinotta, G Kaufman, G Wilson, L Li, M Kohandel, M Scholz, M Scholz, M Scholz, M Zaider, N Hartmann, P Flatt, P Hahnfeldt, R Lee, R Mateuca, R Pathak, R Purrot, S Engen, S Ritter, S Ritter, S Tenhumberg, Sylvia Ritter, T Groesser, U Amaldi, W Chaung, W Feller, W Weyrather, WK Sinclair   +34 more
core   +1 more source