Results 91 to 100 of about 2,432,280 (329)

The Genetic Of Mental Retardation [PDF]

, 2005
Mental retardation is a common problem with major implications for a nation’s health, education and community services. The causes of mental retardation have been found to have a definite etiological basis, which may be biochemical, chromosomal ...
Faradz, Sultana M.H.
core  

Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia

, 2006
Distinct morphologic and clinical features associated with specific chromosomal abnormalities have been described in subgroups of myelodysplastic syndromes (MDS), which often are losses or gains and only rarely translocations.
Johansson, Bertil,, A. Schmitt graff, Johansson, B., Müller-Berndorff, Hendrik, H. Muller berndorff, Kunzmann, R., M. Daskalakis, Mueller-Berndorff, H., B. Johansson, F. Onida, Daskalakis, M., K. Bouabdallah, M. Lubbert, Mauritzson, N., Schmitt-Gräff, Annette, Onida, Francesco, Bouabdallah, K., Mauritzson, Nils, Kunzmann, Regina, Johansson, Bertil, Daskalakis, Michael, Lübbert, Michael, Mauritzson, Nils,, Luebbert, M., Schmitt-Graeff, A., Bouabdallah, Krimo, Lund University., Onida, F., N. Mauritzson, R. Kunzmann   +29 more
core   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

The 5q– Abnormality

, 1987
LOSS OF A PORTION of the long arm of chromosome 5 is seen predominantly in therapy-related myelodysplastic syndromes and acute leukemias, as well as in a unique clinical disorder known as the 5q– syndrome.
Nimer, Stephen D, Golde, David W
core   +1 more source

A case report of Monosomy 21 [PDF]

Journal of Kerman University of Medical Sciences, 1999
monosomy 21 is a rare chromosomal abnormality which is persented in mosaic or homogenous forms.the latter form which is very rare,is determined by intra uterin growth retardation)IUGR),failure to thrive (FTT),prominent craniofacial,skeletal deformities ...
M.H Daei-Parizi, M.H Karininejhad, M GHorbanianfard   +2 more
doaj  

Hydatidiform Mole-Between Chromosomal Abnormality, Uniparental Disomy and Monogenic Variants: A Narrative Review. [PDF]

Life (Basel), 2023
Florea A, Caba L, Grigore AM, Antoci LM, Grigore M, Gramescu MI, Gorduza EV.   +6 more
europepmc   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Meiotic Chromosomal Abnormality Detected in a Heterozygote of Elymus nutans. [PDF]

Front Plant Sci, 2022
Liu B, Tao X, Dou Q.
europepmc   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source