Results 81 to 90 of about 231,455 (290)

Testicular microlithiasis in two boys with a chromosomal abnormality

Indian Journal of Urology, 2012
A nine and 13-year-old boy, previously diagnosed with 18q syndrome and an 11q deletion, respectively were diagnosed with testicular microlithiasis (TM).
Joery Goede, W. W. M Hack, F H Pierik
doaj   +1 more source

Cytogenetic Investigation in Couples with Recurrent Abortion and Poor Obstetric History

Gynecology Obstetrics & Reproductive Medicine, 2010
OBJECTIVES: The cause of recurrent early pregnancy wastage is often unknown. Cytogenetic studies have an important role in the evaluation of couples with repeated miscarriages and poor obstetric history.
Ebru Önalan Etem, Hüseyin Yüce, Deniz Erol, Şükriye Derya Deveci, Hüsnü Çelik, Halit Elyas   +5 more
doaj  

Retrospective Study of B Lymphoblastic Leukemia to Assess the Prevalence of TEL/AML1 in South India: A Study of 214 Cases and Review of Literature

Indian Journal of Medical and Paediatric Oncology
Introduction Translocation t(12;21)(p13;q22), a recurrent and an invisible chromosomal abnormality, resulting in TEL/AML1 gene fusion, associated with good prognosis, has been described to be a common abnormality, in children with B-acute ...
Sandhya Devi G., Faiq Ahmed, Manasi C. Mundada, Rachna Khera, Lavanya Nambaru, Krishnamohan Mallavarapu, Pavan Kumar Boyella, Veerandra Patil, Pallavi Suresh Laddha, Senthil J. Rajappa   +9 more
doaj   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, EarlyView.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

A case report of Monosomy 21 [PDF]

Journal of Kerman University of Medical Sciences, 1999
monosomy 21 is a rare chromosomal abnormality which is persented in mosaic or homogenous forms.the latter form which is very rare,is determined by intra uterin growth retardation)IUGR),failure to thrive (FTT),prominent craniofacial,skeletal deformities ...
M.H Daei-Parizi, M.H Karininejhad, M GHorbanianfard   +2 more
doaj  

Importance Of Prenatal Diagnosis In Patients With History Of Chromosomal Abnormalities

, 2019
The researchers retrospectively evaluated the data of patients who underwent invasive prenatal diagnostic tests with respect to the following risk factors: 1) history of chromosomal abnormality in the family (n=36), 2) history of chromosomal abnormality ...
Yucesoy, Halise Meltem, Unal, Canan, Beksac, M. Sinan, Tanacan, Atakan, Fadiloglu, Erdem, BEKSAÇ, MEHMET SİNAN   +5 more
core   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

CHROMOSOMAL ANALYSIS OF MENTALLY RETARDED CHILDREN WITH MICROCEPHALY [PDF]

, 2011
Background: Mental retardation is a common condition with the incidence of 1- 3% of the entire population; about 25% - 50% of them are genetic causes. Chromosomal causes account for up to 28%.
Afadiyanti, Alfi, Rusdi, Wiyosa Waluyan, Putra, Farmaditya Eka   +2 more
core   +1 more source

Hydatidiform Mole-Between Chromosomal Abnormality, Uniparental Disomy and Monogenic Variants: A Narrative Review. [PDF]

Life (Basel), 2023
Florea A, Caba L, Grigore AM, Antoci LM, Grigore M, Gramescu MI, Gorduza EV.   +6 more
europepmc   +1 more source