Results 101 to 110 of about 2,432,280 (329)

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Women as moral pioneers? Experiences of first trimester antenatal screening

, 2005
Copyright @ 2005 Elsevier Ltd.The implementation of innovative medical technologies can raise unprecedented ethical, legal and social dilemmas. This is particularly so in the area of antenatal screening, which is dominated by the language of risk and ...
Williams, C, Heyman, B, Clare Williams, Spencer, K., Rachel Grellier, Williams, C., Lewandohundt, G., Sandall, J, Grellier, R, Sandall, J., Heyman, Bob, Bob Heyman, Jane Sandall, Lewando-Hundt, G, Spencer, K, Grellier, R., Kevin Spencer, Gillian Lewando-Hundt   +17 more
core   +1 more source

Autophagy-related genes affect the survival of multiple myeloma patients depending on chromosomal abnormality. [PDF]

Asian Biomed (Res Rev News), 2022
Ayna Duran G, Benderli Cihan Y.
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Chromosomal abnormalities and mental illness

, 2003
Linkage studies of mental illness have provided suggestive evidence of susceptibility loci over many broad chromosomal regions. Pinpointing causative gene mutations by conventional linkage strategies alone is problematic.
MacIntyre, D J, Pickard, B S, Blackwood, D H R, Porteous, D J, Muir, W J   +4 more
core   +1 more source

Controlled ovarian hyperstimulation parameters are not associated with de novo chromosomal abnormality rates and clinical pregnancy outcomes in preimplantation genetic testing. [PDF]

Front Endocrinol (Lausanne), 2022
Liu Y, Shen J, Zhang Y, Peng R, Zhao J, Zhou P, Yang R, Guan Y.   +7 more
europepmc   +1 more source

Porokeratosis and Chromosomal Abnormalities [PDF]

Dermatologica, 2009
G, Orecchia, L, Perfetti, S, Scappaticci
openaire   +2 more sources

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Massively parallel sequencing for chromosomal abnormality testing in trophectoderm cells of human blastocysts

, 2013
Preimplantation genetic diagnosis and screening are widely accepted for chromosomal abnormality identification to avoid transferring embryos with genetic defects.
F Mu (9869669), X Yin (7747289), C Lin (7772183), K Tan (7719896), Y Gao (4703698), L Zhao (7930646), C Gong (9869663), X Yi (9869666), X Li (4169308), Y Liang (8261823)   +9 more
core  

Acute Promyelocytic Leukemia with t(2;3): An Unusual Additional Chromosomal Abnormality. [PDF]

Indian J Hematol Blood Transfus, 2022
Gajendra S, Yadav AK, Bhargava M.
europepmc   +1 more source