Results 271 to 280 of about 1,000,004 (376)

Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners.

Proceedings of the National Academy of Sciences of the United States of America, 1987
A. Bakhshi, J. Wright, W. Graninger, M. Seto, J. Owens, J. Cossman, J. Jensen, P. Goldman, S. Korsmeyer   +8 more
semanticscholar   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

The tcl‐3 proto‐oncogene altered by chromosomal translocation in T‐cell leukemia codes for a homeobox protein.

EMBO Journal, 1991
M. Lu, Zhiyuan Gong, W. Shen, A. Ho
semanticscholar   +1 more source

Plant defense strategies: The dual armor of disease resistance and tolerance

New Plant Protection, EarlyView.
Plants employ dual strategies against pathogens: Resistance limits invasion via immune responses, whereas tolerance mitigates damage to sustain growth—together enhancing survival under infections. Abstract Pathogen infections pose a significant threat to plant health, global food security, and ecosystems.
Zhijuan Tang, Shaosong Shi, Xinyu Du, Guoyong Xu   +3 more
wiley   +1 more source

Molecular cytogenetic characterization of wheat-Elymus repens chromosomal translocation lines with resistance to Fusarium head blight and stripe rust. [PDF]

BMC Plant Biol, 2019
Gong B, Zhu W, Li S, Wang Y, Xu L, Wang Y, Zeng J, Fan X, Sha L, Zhang H, Qi P, Huang L, Chen G, Zhou Y, Kang H.   +14 more
europepmc   +1 more source

Upper respiratory tract carcinoma with chromosomal translocation 15;19

Cancer, 2001
S. Vargas, C. French, P. Faul, J. Fletcher, I. Davis, P. Dal Cin, A. Perez-Atayde   +6 more
semanticscholar   +1 more source

DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells

, 2019
Clare C. So, Alberto Martín
openalex   +2 more sources

Genome‐wide analysis of somatic noncoding mutation patterns and mitochondrial heteroplasmic shift in type B1 and B2 thymomas

The Journal of Pathology, EarlyView.
Abstract Type B1 and B2 thymomas are lymphocyte‐rich malignant tumours with few somatic mutations in protein‐coding regions of the nuclear genome; nonetheless, noncoding regions remain uncharacterized. Here, we developed a method to isolate pure thymoma cells from lymphocyte‐rich tissues, and then performed genome‐wide deep sequencing. The total number
Kohei Fujikura, Isabel Correa, Susanne Heck, Kaoru Watanabe, Juliet King, Emma McLean, Susan Ndagire, Yoshihisa Takahashi, Masahiko Kuroda, Andrea Bille, Daisuke Nonaka   +10 more
wiley   +1 more source

The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene.

Blood, 1989
J. Grimaldi, T. Meeker
semanticscholar   +1 more source

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source