Results 1 to 10 of about 60,035 (243)

Visualization of chromosome condensation in plants with large chromosomes [PDF]

open access: yesBMC Plant Biology, 2017
Background Most data concerning chromosome organization have been acquired from studies of a small number of model organisms, the majority of which are mammals.
Maria A. Kuznetsova   +2 more
doaj   +6 more sources

Novel insights into mitotic chromosome condensation [version 1; referees: 2 approved] [PDF]

open access: yesF1000Research, 2016
The fidelity of mitosis is essential for life, and successful completion of this process relies on drastic changes in chromosome organization at the onset of nuclear division.
Ewa Piskadlo, Raquel A. Oliveira
doaj   +6 more sources

A phospho-switch to trigger mitotic chromosome condensation [PDF]

open access: yesBiology Direct
One of the most eye-catching events in cell biology is the condensation of chromosomes. During mitosis, the diffuse interphase chromatin rearranges into compact, rod-shaped chromosomes that can be precisely segregated between the daughter cells.
Alessandro Borsellini
doaj   +2 more sources

Molecular mechanism targeting condensin for chromosome condensation [PDF]

open access: yesThe EMBO Journal
Genomes are organised into DNA loops by the Structural Maintenance of Chromosomes (SMC) proteins. SMCs establish functional chromosomal sub-domains for DNA repair, gene expression and chromosome segregation, but how SMC activity is specifically targeted ...
Menglu Wang   +5 more
doaj   +2 more sources

KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation [PDF]

open access: yesAdvanced Science
Chromosome condensation during mitosis is essential for proper cell division. Histone modifications, particularly the dynamic regulation of active and repressive marks, play a crucial role in this process. However, the mechanisms controlling the temporal
Yena Cho   +6 more
doaj   +2 more sources

Plk1 phosphorylation of CAP-H2 triggers chromosome condensation by condensin II at the early phase of mitosis

open access: yesScientific Reports, 2017
Condensin complexes play crucial roles in chromosome condensation that is a fundamental process to establish the “rod-like” shape of chromosome structure in mitosis.
Yuya Kagami   +2 more
doaj   +2 more sources

The Major Chromosome Condensation Factors Smc, HBsu, and Gyrase in Bacillus subtilis Operate via Strikingly Different Patterns of Motion [PDF]

open access: yesmSphere, 2020
Although DNA-compacting proteins have been extensively characterized in vitro, knowledge of their DNA binding dynamics in vivo is greatly lacking.
Sonja Schibany   +3 more
doaj   +2 more sources

Stable Chromosome Condensation Revealed by Chromosome Conformation Capture. [PDF]

open access: yesCell, 2015
Chemical cross-linking and DNA sequencing have revealed regions of intra-chromosomal interaction, referred to as topologically associating domains (TADs), interspersed with regions of little or no interaction, in interphase nuclei. We find that TADs and the regions between them correspond with the bands and interbands of polytene chromosomes of ...
Eagen KP, Hartl TA, Kornberg RD.
europepmc   +4 more sources

Epigenetic countermarks in mitotic chromosome condensation. [PDF]

open access: yesNucleus, 2017
Mitosis in metazoans is characterized by abundant phosphorylation of histone H3 and involves the recruitment of condensin complexes to chromatin. The relationship between the 2 phenomena and their respective contributions to chromosome condensation in vivo remain poorly understood.
van Wely KH   +3 more
europepmc   +5 more sources

Depletion or cleavage of cohesin during anaphase differentially affects chromatin structure and segregation

open access: yeseLife, 2022
Chromosome segregation requires both the separation of sister chromatids and the sustained condensation of chromatids during anaphase. In yeast cells, cohesin is not only required for sister chromatid cohesion but also plays a major role determining the ...
Jonay Garcia-Luis   +4 more
doaj   +1 more source

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