Results 21 to 30 of about 60,035 (243)
eLife, 2022 Type II topoisomerases modulate chromosome supercoiling, condensation, and catenation by moving one double-stranded DNA segment through a transient break in a second duplex.
Joshua Jeong +4 more
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Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function. [PDF]
PLoS ONE, 2010 Mutations in the human gene MCPH1 cause primary microcephaly associated with a unique cellular phenotype with premature chromosome condensation (PCC) in early G2 phase and delayed decondensation post-mitosis (PCC syndrome).
Marc Trimborn +20 more
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Mechanics of Sister Chromatids studied with a Polymer Model
Frontiers in Physics, 2013 Sister chromatid cohesion denotes the phenomenon that sister chromatids are initially attached to each other in mitosis to guarantee the error-free distribution into the daughter cells.
Yang eZhang +3 more
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BMC Research Notes, 2020 Objective Structural maintenance of chromosomes (SMC) proteins are key players in chromosome dynamics in all types of organisms. The so-called condensin subfamily is essential for chromosome condensation in eukaryotic cells, as is the bacterial SMC ...
Tobias Knust, Peter L. Graumann
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Fold-change of chromatin condensation in yeast is a conserved property
Scientific Reports, 2022 During mitosis, chromatin is condensed and organized into mitotic chromosomes. Condensation is critical for genome stability and dynamics, yet the degree of condensation is significantly different between multicellular and single-cell eukaryotes. What is
Katreena Yamin +9 more
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A low Smc flux avoids collisions and facilitates chromosome organization in Bacillus subtilis
eLife, 2021 SMC complexes are widely conserved ATP-powered DNA-loop-extrusion motors indispensable for organizing and faithfully segregating chromosomes. How SMC complexes translocate along DNA for loop extrusion and what happens when two complexes meet on the same ...
Anna Anchimiuk +5 more
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Condensation patterns of prophase/prometaphase chromosome are correlated with H4K5 histone acetylation and genomic DNA contents in plants. [PDF]
PLoS ONE, 2017 Mitotic prophase chromosome condensation plays an essential role in nuclear division being therefore regulated by highly conserved mechanisms. However, degrees of chromatin condensation in prophase-prometaphase cells may vary along the chromosomes ...
Lidiane Feitoza +2 more
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Chromosome condensation: Packaging the genome [PDF]
Current Biology, 2001 The packaging of centimetre long DNA molecules into compact metaphase chromosomes is essential for genome segregation in anaphase. The chromosomal condensin complex plays a crucial part in this packaging, and important new insight into condensin action in vitro and in vivo has recently been gained.
openaire +2 more sources
Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation
Molecular Cytogenetics, 2010 Mitotic cell death is an important form of cell death, particularly in cancer. Chromosome fragmentation is a major form of mitotic cell death which is identifiable during common cytogenetic analysis by its unique phenotype of progressively degraded ...
Bremer Steven W +6 more
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Marine Drugs, 2015 Lasonolide A (LSA), a potent antitumor polyketide from the marine sponge, Forcepia sp., induces rapid and reversible protein hyperphosphorylation and premature chromosome condensation (PCC) at nanomolar concentrations independent of cyclin-dependent ...
Rozenn Jossé +5 more
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