Results 191 to 200 of about 1,593,998 (268)

Genomic Investigations Unveil the Genetic Underpinnings of Environmental Adaptation in African Goat Populations

open access: yesIntegrative Zoology, EarlyView.
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng   +19 more
wiley   +1 more source

Integrated Multi‐Omics Analysis Reveals the Genetic Basis of Phenotypic Variation in Tibetan Sheep

open access: yesIntegrative Zoology, EarlyView.
SNaPshot‐validated GWAS results demonstrated significant correlations between candidate single nucleotide polymorphisms (SNPs) and body size traits in Tibetan sheep. Concurrently, hematoxylin and eosin staining, alongside muscle fiber analysis, confirmed pronounced morphological differences in muscle tissue between sheep of varying conformation.
Dehui Liu   +16 more
wiley   +1 more source

CiFi: accurate long-read chromosome conformation capture with low-input requirements. [PDF]

open access: yesNat Commun
McGinty SP   +10 more
europepmc   +1 more source

Some Tuco‐Tucos Hide More Than Others: An Integrative Approach Reveals Cryptic Diversity in Ctenomys (Rodentia: Ctenomyidae) From Central Argentina

open access: yesIntegrative Zoology, EarlyView.
Here, we adopt an integrative framework (molecular phylogenetics and geometric morphometrics) to reassess patterns of diversity and differentiation across this region. We analyzed cytochrome b sequences and quantified cranial shape variation. Our analyses indicate the presence of three species groups (mendocinus, talarum, and tucumanus) and two ...
Facundo Contreras   +4 more
wiley   +1 more source

A prostate cancer-specific super-enhancer at 1q42.3 regulates the CAPN2 and KRT19. [PDF]

open access: yesJ Biol Chem
Zhao Z   +13 more
europepmc   +1 more source

Inhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi

open access: yesIntegrative Zoology, EarlyView.
① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li   +16 more
wiley   +1 more source

Chromosome‐Level Genome Assembly of Strauchbufo raddei and Multi‐Omic Insights Into Drought Adaptation

open access: yesIntegrative Zoology, EarlyView.
ABSTRACT Understanding how amphibians adapt to terrestrial and arid environments is important for elucidating vertebrate terrestrialization. In this study, we present the first chromosome‐level, high‐quality genome assembly of Strauchbufo raddei, constructed using PacBio HiFi long‐read sequencing and Hi‐C scaffolding. The assembled genome is 4.47 Gb in
Fanrui Chen   +7 more
wiley   +1 more source

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