Results 81 to 90 of about 11,267,652 (394)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Chromosome Number of Cardamine pratensis [PDF]
Nature, 1948 I NOTICE with interest Dr. Howard‘s records of chromosome counts of 2n = 56 for several plants of Cardamine pratensis growing in damp places1. I have been working on British plants of this species for the last two years, with the help and guidance of Dr. K. B.
openaire +5 more sources
Morphometric Variations Between Triploid and Diploid Clarias gariepinus (Burchell, 1822)
Croatian Journal of Fisheries, 2017 Several scientific methods have been described in the identification of triploid fish. However, many of these methods are not applicable for routine management purposes due to their complexity and cost.
Normala Jalil +6 more
doaj +1 more source
Frontiers in Plant Science, 2021 The mainly Australian grass genus Austrostipa (tribe Stipeae) comprising approximately 64 species represents a remarkable example of an evolutionary radiation.
Natalia Tkach +7 more
doaj +1 more source
GENESPACE tracks regions of interest and gene copy number variation across multiple genomes
eLife, 2022 The development of multiple chromosome-scale reference genome sequences in many taxonomic groups has yielded a high-resolution view of the patterns and processes of molecular evolution.
J. Lovell +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Flow cytometry and chromosome numbers variation in argan tree Argania spinosa (L.) Skeels
Notulae Scientia Biologicae, 2023 Argania spinosa L. Skeels is an endemic species of west-central Morocco, which is characterized by a high diversity of morphological and genetic traits. It constitutes a natural resource for oleo-agro-sylvo-pastoral uses.
Ali EL BOUKHARI +8 more
doaj +1 more source
GenomeFingerprinter and universal genome fingerprint analysis for systematic comparative genomics [PDF]
, 2013 How to compare whole genome sequences at large scale has not been achieved via conventional methods based on pair-wisely base-to-base comparison; nevertheless, no attention was paid to handle in-one-sitting a number of genomes crossing genetic category ...
Ai, Hannan +3 more
core +4 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Multidirectional chromosome painting substantiates the occurrence of extensive genomic reshuffling within Accipitriformes. [PDF]
, 2015 BACKGROUND: Previous cross-species painting studies with probes from chicken (Gallus gallus) chromosomes 1-10 and a paint pool of nineteen microchromosomes have revealed that the drastic karyotypic reorganization in Accipitridae is due to extensive ...
Beiyuan Fu +10 more
core +4 more sources