Results 1 to 10 of about 405,684 (326)

Bacterial chromosome organization. II. Few special cross-links, cell confinement, and molecular crowders play the pivotal roles [PDF]

, 2019
Using a bead-spring model of bacterial DNA polymers of {\em C. crescentus} and {\em E. coli} we show that just $33$ and $38$ effective cross-links at special positions along the chain contour of the DNA can lead to the large-scale organization of the DNA
Tejal Agarwal, G. P. Manjunath, Farhat Habib, A. C. Chatterji   +3 more
openalex   +3 more sources

Chromosome Organization in Early Meiotic Prophase [PDF]

Frontiers in Cell and Developmental Biology, 2021
One of the most fascinating aspects of meiosis is the extensive reorganization of the genome at the prophase of the first meiotic division (prophase I). The first steps of this reorganization are observed with the establishment of an axis structure, that
Corinne Grey, Bernard de Massy
doaj   +2 more sources

A low Smc flux avoids collisions and facilitates chromosome organization in Bacillus subtilis [PDF]

eLife, 2021
SMC complexes are widely conserved ATP-powered DNA-loop-extrusion motors indispensable for organizing and faithfully segregating chromosomes. How SMC complexes translocate along DNA for loop extrusion and what happens when two complexes meet on the same ...
Anna Anchimiuk, Virginia S Lioy, Florian Patrick Bock, Anita Minnen, Frederic Boccard, Stephan Gruber   +5 more
doaj   +2 more sources

Chromosome organization by one-sided and two-sided loop extrusion [PDF]

eLife, 2020
SMC complexes, such as condensin or cohesin, organize chromatin throughout the cell cycle by a process known as loop extrusion. SMC complexes reel in DNA, extruding and progressively growing DNA loops.
Edward J Banigan, Aafke A van den Berg, Hugo B Brandão, John F Marko, Leonid A Mirny   +4 more
doaj   +2 more sources

Coupling chromosome organization to genome segregation in Archaea [PDF]

Nature Communications
Chromosome segregation is a fundamental process in all life forms and requires coordination with genome organization, replication and cell division. The mechanism that mediates chromosome segregation in archaea remains enigmatic.
Azhar F. Kabli, Irene W. Ng, Nicholas Read, Parul Pal, Julia Reimann, Ngat T. Tran, Sonja-Verena Albers, Tung B. K. Le, Daniela Barillà   +8 more
doaj   +3 more sources

Acyl carrier protein promotes MukBEF action in Escherichia coli chromosome organization-segregation. [PDF]

Nat Commun, 2021
Prince JP, Bolla JR, Fisher GLM, Mäkelä J, Fournier M, Robinson CV, Arciszewska LK, Sherratt DJ.   +7 more
europepmc   +3 more sources

Chromosome organization by fine-tuning an ATPase. [PDF]

Genes Dev, 2023
Massari LF, Marston AL.
europepmc   +3 more sources

MCMBP promotes the assembly of the MCM2–7 hetero-hexamer to ensure robust DNA replication in human cells

eLife, 2022
The MCM2–7 hetero-hexamer is the replicative DNA helicase that plays a central role in eukaryotic DNA replication. In proliferating cells, the expression level of the MCM2–7 hexamer is kept high, which safeguards the integrity of the genome. However, how
Yuichiro Saito, Venny Santosa, Kei-ichiro Ishiguro, Masato T Kanemaki   +3 more
doaj   +1 more source

Spatial Chromosome Organization and Adaptation of Escherichia coli under Heat Stress [PDF]

Microorganisms
Xu-Ting Wang, Bin‐Guang Ma
europepmc   +3 more sources

Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage

Nature Communications, 2022
During meiosis, the number and distribution of crossovers (COs) are tightly controlled, but the mechanistic basis of this control is unclear. Here, by combining experimental data and mathematical modeling, the study advocates a CO patterning model via ...
Stéphanie Durand, Qichao Lian, Juli Jing, Marcel Ernst, Mathilde Grelon, David Zwicker, Raphael Mercier   +6 more
doaj   +1 more source