Results 51 to 60 of about 2,331,002 (344)

Finding the Correct Partner: The Meiotic Courtship

open access: yesScientifica, 2012
Homologous chromosomes are usually separated at the entrance of meiosis; how they become paired is one of the outstanding mysteries of the meiotic process.
Tomás Naranjo
doaj   +1 more source

HAL-2 promotes homologous pairing during Caenorhabditis elegans meiosis by antagonizing inhibitory effects of synaptonemal complex precursors.

open access: yesPLoS Genetics, 2012
During meiosis, chromosomes align with their homologous pairing partners and stabilize this alignment through assembly of the synaptonemal complex (SC). Since the SC assembles cooperatively yet is indifferent to homology, pairing and SC assembly must be ...
Weibin Zhang   +9 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Induced chromosome pairing

open access: yesCalifornia Agriculture, 1982
Not available – first paragraph follows: Success in hybridizing wild with cultivated species ultimately depends on the ability of the alien chromosomes to pair and recombine with the chromosomes of the crop species at meiosis.
J Irvine, P McGuire
doaj  

An increasing need for productive and stress resilient Festulolium amphiploids: what can be learnt from the stable genomic composition of Festuca pratensis subsp. apennina (De Not.) Hegi?

open access: yesFrontiers in Environmental Science, 2016
Genome composition of Festuca pratensis subsp. apennina (De Not.) Hegi, a tetraploid fescue species native to the tall forbs communities of south-eastern Europe at altitudes between 1100 and 2200m a.s.l.
David Kopecký   +10 more
doaj   +1 more source

Dynamics of DNA replication during premeiosis and early meiosis in wheat. [PDF]

open access: yesPLoS ONE, 2014
Meiosis is a specialised cell division that involves chromosome replication, two rounds of chromosome segregation and results in the formation of the gametes.
María-Dolores Rey, Pilar Prieto
doaj   +1 more source

Homoeologous chromosome pairing between the A and B genomes of Musa spp. revealed by genomic in situ hybridization.

open access: yesAnnals of Botany, 2011
BACKGROUND AND AIMS Most cooking banana and several desert bananas are interspecific triploid hybrids between Musa acuminata (A genome) and Musa balbisiana (B genome). In addition, M.
M. Jeridi   +7 more
semanticscholar   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Surveillance of cohesin-supported chromosome structure controls meiotic progression

open access: yesNature Communications, 2020
Meiosis-specific cohesins and the synaptonemal complex are essential for meiotic chromosome structure and function. Here the authors show that continued surveillance of these chromosome structures controls meiotic progression by regulating CHK-2, a ...
Maikel Castellano-Pozo   +6 more
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

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