Results 61 to 70 of about 2,401,068 (320)

Dynamics of DNA replication during premeiosis and early meiosis in wheat. [PDF]

open access: yesPLoS ONE, 2014
Meiosis is a specialised cell division that involves chromosome replication, two rounds of chromosome segregation and results in the formation of the gametes.
María-Dolores Rey, Pilar Prieto
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Introgression of the Aegilops speltoides Su1-Ph1 Suppressor into Wheat

open access: yesFrontiers in Plant Science, 2017
Meiotic pairing between homoeologous chromosomes in polyploid wheat is inhibited by the Ph1 locus on the long arm of chromosome 5 in the B genome.
Hao Li   +5 more
doaj   +1 more source

Sequence analysis of wheat subtelomeres reveals a high polymorphism among homoeologous chromosomes

open access: yesThe Plant Genome, 2020
Bread wheat, Triticum aestivum L., is one of the most important crops in the world. Understanding its genome organization (allohexaploid; AABBDD; 2n = 6x = 42) is essential for geneticists and plant breeders. Particularly, the knowledge of how homologous
Miguel Aguilar, Pilar Prieto
doaj   +1 more source

Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. [PDF]

open access: yesPLoS Genetics, 2012
Recent studies in simple model organisms have shown that centromere pairing is important for ensuring high-fidelity meiotic chromosome segregation. However, this process and the mechanisms regulating it in higher eukaryotes are unknown.
C Gaston Bisig   +6 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

New cytogenetic data on Nabidae (Heteroptera: Cimicomorpha), with a discussion of karyotype variation and meiotic patterns, and their taxonomic significance

open access: yesEuropean Journal of Entomology, 2004
As a part of ongoing cytogenetic studies on the bug family Nabidae (Heteroptera), the karyotypes and meiotic patterns of male Nabis (Aspilaspis) viridulus Spinola, 1837, N.
Valentina G. KUZNETSOVA   +2 more
doaj   +1 more source

The subtelomeric region is important for chromosome recognition and pairing during meiosis

open access: yesScientific Reports, 2014
The process of meiosis results in the formation of haploid daughter cells, each of which inherit a half of the diploid parental cells' genetic material.
M. Calderón   +3 more
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

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