Results 61 to 70 of about 2,725,833 (311)
Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]
, 2018 Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core +1 more source
Annals of Botany, 2011 Background and Aims Lady's slipper orchids (Paphiopedilum) are of high value in floriculture, and interspecific hybridization has long been used for breeding improved cultivars; however, information regarding the genome affinities of species and ...
Yung-I. Lee, Fang-Chi Chang, M. Chung
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
PLoS Genetics, 2015 The spatial organization of chromosomes within interphase nuclei is important for gene expression and epigenetic inheritance. Although the extent of physical interaction between chromosomes and their degree of compaction varies during development and ...
Huy Q Nguyen +5 more
doaj +1 more source
CYTOGENETICS OF CHROMOSOME PAIRING IN WHEAT [PDF]
Genetics, 1974 ABSTRACT Meiotic chromosome pairing in Triticum aestivum is controlled by genetic systems promoting and reducing pairing. The pairing of homoeologous chromosomes is prevented principally by the activity of a single locus (Ph) distally located on the long arm of chromosome 5B.
openaire +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
X-inactivation by chromosomal pairing events [PDF]
Genes & Development, 1999 X-inactivation is the coordinated silencing of nearly all genes on one of the two X chromosomes in female mammals. X-inactivation requires the cis-acting Xist gene. The highly unusual properties of Xist and the extremely long distances over which Xist acts have made it difficult to reconcile X-inactivation with other examples of gene regulation.
openaire +2 more sources
Oligopaint DNA FISH reveals telomere-based meiotic pairing dynamics in the silkworm, Bombyx mori.
PLoS Genetics, 2021 Accurate chromosome segregation during meiosis is essential for reproductive success. Yet, many fundamental aspects of meiosis remain unclear, including the mechanisms regulating homolog pairing across species.
Leah F Rosin +3 more
doaj +1 more source
Frontiers in Plant Science, 2022 Effective utilization of genetic diversity in wild relatives to improve wheat requires recombination between wheat and alien chromosomes. However, this is suppressed by the Pairing homoeologous gene, Ph1, on the long arm of wheat chromosome 5B.
Edina Türkösi +14 more
doaj +1 more source
Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. [PDF]
, 2020 Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Acevedo, David +7 more
core +3 more sources