Results 11 to 20 of about 44,353 (314)
Crosstalk Regulation Between Bacterial Chromosome Replication and Chromosome Partitioning [PDF]
Frontiers in Microbiology, 2019 Despite much effort, the bacterial cell cycle has proved difficult to study and understand. Bacteria do not conform to the standard eukaryotic model of sequential cell-cycle phases. Instead, for example, bacteria overlap their phases of chromosome replication and chromosome partitioning.
Gregory T. Marczynski +2 more
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A novel nucleoid-associated protein coordinates chromosome replication and chromosome partition. [PDF]
Nucleic Acids Res, 2017 We searched for regulators of chromosome replication in the cell cycle model Caulobacter crescentus and found a novel DNA-binding protein (GapR) that selectively aids the initiation of chromosome replication and the initial steps of chromosome partitioning. The protein binds the chromosome origin of replication (Cori) and has higher-affinity binding to
Taylor JA +3 more
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Plasmid and chromosome partitioning: surprises from phylogeny [PDF]
Molecular Microbiology, 2000 Plasmids encode partitioning genes (par) that are required for faithful plasmid segregation at cell division. Initially, par loci were identified on plasmids, but more recently they were also found on bacterial chromosomes. We present here a phylogenetic analysis of par loci from plasmids and chromosomes from prokaryotic organisms.
Kenn Gerdes +2 more
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Psammaplysin F: A unique inhibitor of bacterial chromosomal partitioning
Bioorganic & Medicinal Chemistry Letters, 2013 Described is the antibiotic activity of a marine natural product. Psammaplysin F (1) inhibited the growth of four Gram-positive strains by >80% at 50μM, and the amine at position C-20 is responsible for the observed antibacterial activity. When tested against two strains of methicillin resistant Staphylococcus aureus (MRSA), the minimum inhibitory ...
Deborah M. Ramsey +5 more
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Vibrio cholerae Chromosome Partitioning without Polar Anchoring by HubP [PDF]
Genes, 2022 Partition systems are widespread among bacterial chromosomes. They are composed of two effectors, ParA and ParB, and cis acting sites, parS, located close to the replication origin of the chromosome (oriC). ParABS participate in chromosome segregation, at least in part because they serve to properly position sister copies of oriC.
Christophe Possoz +4 more
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Abortive recombination in Escherichia coli ruv mutants blocks chromosome partitioning [PDF]
Genes to Cells, 1998 Background:All the ruvA, ruvB and ruvC mutants of Escherichia coli are sensitive to treatments that damage DNA, and are mildly defective in homologous recombination. It has been reported that the ruv mutants form nonseptate, multinuclear filaments after low doses of UV irradiation, dependent on the sfiA gene product.
Ken Ishioka +4 more
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Partition of distinct chromosomal regions: negotiable border and fixed border [PDF]
Genes to Cells, 2004 Chromosomes are partitioned into distinct functional regions. For example, heterochromatin regions consist of condensed chromatin and contain few transcriptionally active genes, whereas euchromatin regions are less condensed and majority of active genes reside in the euchromatin regions.
Akatsuki Kimura, Masami Horikoshi
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Characterization of chromosomal and megaplasmid partitioning loci in Thermus thermophilus HB27 [PDF]
BMC Genomics, 2015 In low-copy-number plasmids, the partitioning loci (par) act to ensure proper plasmid segregation and copy number maintenance in the daughter cells. In many bacterial species, par gene homologues are encoded on the chromosome, but their function is much less understood.
Haijuan Li +4 more
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Postseptational chromosome partitioning in bacteria. [PDF]
Proceedings of the National Academy of Sciences, 1995 Mutations in the spoIIIE gene prevent proper partitioning of one chromosome into the developing prespore during sporulation but have no overt effect on partitioning in vegetatively dividing cells. However, the expression of spoIIIE in vegetative cells and the occurrence of genes closely related to spoIIIE in a range of nonsporulating eubacteria ...
Michaela Sharpe, Jeff Errington
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ARID1A spatially partitions interphase chromosomes [PDF]
Science Advances, 2019 ARID1A is important for genome folding, spatial partitioning of interphase chromosomes, and intermixing of small chromosomes.
Shuai Wu +12 more
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