Regional Control of Chromosome Segregation in Pseudomonas aeruginosa. [PDF]
PLoS Genetics, 2016 Chromosome segregation in bacteria occurs concomitantly with DNA replication, and the duplicated regions containing the replication origin oriC are generally the first to separate and migrate to their final specific location inside the cell.
Valentine Lagage +2 more
doaj +1 more source
Major Reorganization of Chromosome Conformation During Muscle Development in Pig
Frontiers in Genetics, 2021 The spatial organization of the genome in the nucleus plays a crucial role in eukaryotic cell functions, yet little is known about chromatin structure variations during late fetal development in mammals.
Maria Marti-Marimon +7 more
doaj +1 more source
Structural fingerprints of transcription factor binding site regions [PDF]
, 2009 Fourier transforms are a powerful tool in the prediction of DNA sequence properties, such as the presence/absence of codons. We have previously compiled a database of the structural properties of all 32,896 unique DNA octamers.
Christopher Hunter +8 more
core +2 more sources
Spatial ordering of chromosomes enhances the fidelity of chromosome partitioning in cyanobacteria [PDF]
Proceedings of the National Academy of Sciences, 2012 Many cyanobacteria have been shown to harbor multiple chromosome copies per cell, yet little is known about the organization, replication, and segregation of these chromosomes. Here, we visualize individual chromosomes in the cyanobacterium Synechococcus elongatus via time-lapse fluorescence microscopy. We find that
Isha H, Jain +2 more
openaire +2 more sources
A novel mutation of X‐linked recessive deafness gene POU3F4 in a boy with congenital deafness
Laryngoscope Investigative Otolaryngology, 2022 Purpose To report an interstitial deletion of Xq21.1 in chromosome X in a boy with congenital deafness. Methods The proband underwent a thorough physical examination and a detailed audiological and temporal bone computed tomography (CT) scan.
Rong Yu +3 more
doaj +1 more source
Redefining bacterial origins of replication as centralized information processors
Frontiers in Microbiology, 2015 In this review we stress the differences between eukaryotes and bacteria with respect to their different cell cycles, replication mechanisms and genome organizations.
Gregory eMarczynski +2 more
doaj +1 more source
Dynamic nature of SecA and its associated proteins in Escherichia coli.
Frontiers in Microbiology, 2015 Mechanical properties such as physical constraint and pushing of chromosomes are thought to be important for chromosome segregation in Escherichia coli and it could be mediated by a hypothetical molecular tether.
Shun eAdachi +4 more
doaj +1 more source
eLife, 2021 ParABS partition systems, comprising the centromere-like DNA sequence parS, the parS-binding ParB-CTPase, and the nucleoid-binding ParA-ATPase, ensure faithful segregation of bacterial chromosomes and low-copy-number plasmids.
James A Taylor +4 more
doaj +1 more source
Spatial clustering of array CGH features in combination with hierarchical multiple testing [PDF]
, 2010 We propose a new approach for clustering DNA features using array CGH data from multiple tumor samples. We distinguish data-collapsing: joining contiguous DNA clones or probes with extremely similar data into regions, from clustering: joining contiguous,
Kim, Kyung In +2 more
core +8 more sources
Diverse Partners of the Partitioning ParB Protein in Pseudomonas aeruginosa
Microbiology Spectrum, 2023 In the majority of bacterial species, the tripartite ParAB-parS system, composed of an ATPase (ParA), a DNA-binding protein (ParB), and its target parS sequence(s), assists in the chromosome partitioning.
Adam Kawalek +7 more
doaj +1 more source