Results 21 to 30 of about 476,637 (284)

Introducing Modularity and Homology in Grammatical Evolution to Address the Analog Electronic Circuit Design Problem

open access: yesIEEE Access, 2020
We present a new approach based on grammatical evolution (GE) aimed at addressing the analog electronic circuit design problem. In the new approach, called multi-grammatical evolution (MGE), a chromosome is a variable-length codon string that is divided ...
Federico Castejon, Enrique J. Carmona
doaj   +1 more source

Regional Control of Chromosome Segregation in Pseudomonas aeruginosa. [PDF]

open access: yesPLoS Genetics, 2016
Chromosome segregation in bacteria occurs concomitantly with DNA replication, and the duplicated regions containing the replication origin oriC are generally the first to separate and migrate to their final specific location inside the cell.
Valentine Lagage   +2 more
doaj   +1 more source

Accounting for heteroscedasticity and censoring in chromosome partitioning analyses [PDF]

open access: yesEvolution Letters, 2018
AbstractA fundamental assumption in quantitative genetics is that traits are controlled by many loci of small effect. Using genomic data, this assumption can be tested using chromosome partitioning analyses, where the proportion of genetic variance for a trait explained by each chromosome (h2c), is regressed on its size.
Petri Kemppainen, Arild Husby
openaire   +4 more sources

Dynamic nature of SecA and its associated proteins in Escherichia coli.

open access: yesFrontiers in Microbiology, 2015
Mechanical properties such as physical constraint and pushing of chromosomes are thought to be important for chromosome segregation in Escherichia coli and it could be mediated by a hypothetical molecular tether.
Shun eAdachi   +4 more
doaj   +1 more source

A novel mutation of X‐linked recessive deafness gene POU3F4 in a boy with congenital deafness

open access: yesLaryngoscope Investigative Otolaryngology, 2022
Purpose To report an interstitial deletion of Xq21.1 in chromosome X in a boy with congenital deafness. Methods The proband underwent a thorough physical examination and a detailed audiological and temporal bone computed tomography (CT) scan.
Rong Yu   +3 more
doaj   +1 more source

Major Reorganization of Chromosome Conformation During Muscle Development in Pig

open access: yesFrontiers in Genetics, 2021
The spatial organization of the genome in the nucleus plays a crucial role in eukaryotic cell functions, yet little is known about chromatin structure variations during late fetal development in mammals.
Maria Marti-Marimon   +7 more
doaj   +1 more source

The extrusion-capture model for chromosome partitioning in bacteria [PDF]

open access: yesGenes & Development, 2001
Successful cellular reproduction requires accurate duplication and partitioning (segregation) of the genome. Failure to correctly partition the sister genomes results in aneuploidy. The consequences of these errors range from loss of normal cellular function (e.g., the loss of normal growth controls in tumor cells) to cell death.
K P, Lemon, A D, Grossman
openaire   +2 more sources

Plasmid and chromosome partitioning: surprises from phylogeny [PDF]

open access: yesMolecular Microbiology, 2000
Plasmids encode partitioning genes (par) that are required for faithful plasmid segregation at cell division. Initially, par loci were identified on plasmids, but more recently they were also found on bacterial chromosomes. We present here a phylogenetic analysis of par loci from plasmids and chromosomes from prokaryotic organisms.
Gerdes K, Møller-Jensen J, Jensen RB
openaire   +4 more sources

CTP and parS coordinate ParB partition complex dynamics and ParA-ATPase activation for ParABS-mediated DNA partitioning

open access: yeseLife, 2021
ParABS partition systems, comprising the centromere-like DNA sequence parS, the parS-binding ParB-CTPase, and the nucleoid-binding ParA-ATPase, ensure faithful segregation of bacterial chromosomes and low-copy-number plasmids.
James A Taylor   +4 more
doaj   +1 more source

Diverse Partners of the Partitioning ParB Protein in Pseudomonas aeruginosa

open access: yesMicrobiology Spectrum, 2023
In the majority of bacterial species, the tripartite ParAB-parS system, composed of an ATPase (ParA), a DNA-binding protein (ParB), and its target parS sequence(s), assists in the chromosome partitioning.
Adam Kawalek   +7 more
doaj   +1 more source

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