Results 21 to 30 of about 44,353 (314)
Random Chromosome Partitioning in the Polyploid BacteriumThermus thermophilusHB27 [PDF]
G3 Genes|Genomes|Genetics, 2019 AbstractLittle is known about chromosome segregation in polyploid prokaryotes. In this study, whether stringent or variable chromosome segregation occurs in polyploid thermophilic bacterium Thermus thermophilus was analyzed. A stable heterozygous strain (HL01) containing two antibiotic resistance markers at one gene locus was generated. The inheritance
Haijuan Li
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Targeting the chromosome partitioning protein ParA in tuberculosis drug discovery [PDF]
Journal of Antimicrobial Chemotherapy, 2010 To identify inhibitors of the essential chromosome partitioning protein ParA that are active against Mycobacterium tuberculosis.Antisense expression of the parA orthologue MSMEG_6939 was induced on the Mycobacterium smegmatis background. Screening of synthetic chemical libraries was performed to identify compounds with higher anti-mycobacterial ...
Sobia Nisa +6 more
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Virtual partition digital PCR for high precision chromosomal counting applications [PDF]
Analytical Chemistry, 2021 AbstractDigital PCR (dPCR) is the gold standard analytical platform for rapid high precision quantification of genomic fragments. However, current dPCR assays are generally limited to monitoring 1-2 analytes per sample, thereby limiting the platform’s ability to address some clinical applications that require the simultaneous monitoring of 20 – 50 ...
Lucien Jacky +7 more
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The two Cis-acting sites, parS1 and oriC1, contribute to the longitudinal organisation of Vibrio cholerae chromosome I. [PDF]
PLoS Genetics, 2014 The segregation of bacterial chromosomes follows a precise choreography of spatial organisation. It is initiated by the bipolar migration of the sister copies of the replication origin (ori).
Ariane David +5 more
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A fast-partitioning decision method for demand side resources based on grid resilience assessment
Frontiers in Energy Research, 2023 With the large-scale renewable energy integrated into the distribution grid, the grid’s regulating ability and disturbance tolerance are weakening. When partitioning demand-side resources, it is necessary to enhance resilience to ensure the reliability ...
Yueping Kong +6 more
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Partition of P1 plasmids in Escherichia coli mukB chromosomal partition mutants [PDF]
Journal of Bacteriology, 1995 The partition system of the low-copy-number plasmid/prophage of bacteriophage P1 encodes two proteins, ParA and ParB, and contains a DNA site called parS. ParB and the Escherichia coli protein IHF bind to parS to form the partition complex, in which parS is wrapped around ParB and IHF in a precise three-dimensional conformation.
B E, Funnell, L, Gagnier
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Male meiotic spindle features that efficiently segregate paired and lagging chromosomes
eLife, 2020 Chromosome segregation during male meiosis is tailored to rapidly generate multitudes of sperm. Little is known about mechanisms that efficiently partition chromosomes to produce sperm.
Gunar Fabig +9 more
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IMACULAT - an open access package for the quantitative analysis of chromosome localization in the nucleus. [PDF]
PLoS ONE, 2013 The alteration in the location of the chromosomes within the nucleus upon action of internal or external stimuli has been implicated in altering genome function.
Ishita Mehta +2 more
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Centromere Binding and Evolution of Chromosomal Partition Systems in the Burkholderiales [PDF]
Journal of Bacteriology, 2012 ABSTRACTHow split genomes arise and evolve in bacteria is poorly understood. Since each replicon of such genomes encodes a specific partition (Par) system, the evolution of Par systems could shed light on their evolution. The cystic fibrosis pathogenBurkholderia cenocepaciahas three chromosomes (c1, c2, and c3) and one plasmid (pBC), whose ...
Fanny M. Passot +4 more
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IEEE Access, 2020 We present a new approach based on grammatical evolution (GE) aimed at addressing the analog electronic circuit design problem. In the new approach, called multi-grammatical evolution (MGE), a chromosome is a variable-length codon string that is divided ...
Federico Castejon, Enrique J. Carmona
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