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We present a new approach based on grammatical evolution (GE) aimed at addressing the analog electronic circuit design problem. In the new approach, called multi-grammatical evolution (MGE), a chromosome is a variable-length codon string that is divided ...
Federico Castejon, Enrique J. Carmona
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Regional Control of Chromosome Segregation in Pseudomonas aeruginosa. [PDF]
Chromosome segregation in bacteria occurs concomitantly with DNA replication, and the duplicated regions containing the replication origin oriC are generally the first to separate and migrate to their final specific location inside the cell.
Valentine Lagage +2 more
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Accounting for heteroscedasticity and censoring in chromosome partitioning analyses [PDF]
AbstractA fundamental assumption in quantitative genetics is that traits are controlled by many loci of small effect. Using genomic data, this assumption can be tested using chromosome partitioning analyses, where the proportion of genetic variance for a trait explained by each chromosome (h2c), is regressed on its size.
Petri Kemppainen, Arild Husby
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Dynamic nature of SecA and its associated proteins in Escherichia coli.
Mechanical properties such as physical constraint and pushing of chromosomes are thought to be important for chromosome segregation in Escherichia coli and it could be mediated by a hypothetical molecular tether.
Shun eAdachi +4 more
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A novel mutation of X‐linked recessive deafness gene POU3F4 in a boy with congenital deafness
Purpose To report an interstitial deletion of Xq21.1 in chromosome X in a boy with congenital deafness. Methods The proband underwent a thorough physical examination and a detailed audiological and temporal bone computed tomography (CT) scan.
Rong Yu +3 more
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Major Reorganization of Chromosome Conformation During Muscle Development in Pig
The spatial organization of the genome in the nucleus plays a crucial role in eukaryotic cell functions, yet little is known about chromatin structure variations during late fetal development in mammals.
Maria Marti-Marimon +7 more
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The extrusion-capture model for chromosome partitioning in bacteria [PDF]
Successful cellular reproduction requires accurate duplication and partitioning (segregation) of the genome. Failure to correctly partition the sister genomes results in aneuploidy. The consequences of these errors range from loss of normal cellular function (e.g., the loss of normal growth controls in tumor cells) to cell death.
K P, Lemon, A D, Grossman
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Plasmid and chromosome partitioning: surprises from phylogeny [PDF]
Plasmids encode partitioning genes (par) that are required for faithful plasmid segregation at cell division. Initially, par loci were identified on plasmids, but more recently they were also found on bacterial chromosomes. We present here a phylogenetic analysis of par loci from plasmids and chromosomes from prokaryotic organisms.
Gerdes K, Møller-Jensen J, Jensen RB
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ParABS partition systems, comprising the centromere-like DNA sequence parS, the parS-binding ParB-CTPase, and the nucleoid-binding ParA-ATPase, ensure faithful segregation of bacterial chromosomes and low-copy-number plasmids.
James A Taylor +4 more
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Diverse Partners of the Partitioning ParB Protein in Pseudomonas aeruginosa
In the majority of bacterial species, the tripartite ParAB-parS system, composed of an ATPase (ParA), a DNA-binding protein (ParB), and its target parS sequence(s), assists in the chromosome partitioning.
Adam Kawalek +7 more
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