Results 61 to 70 of about 44,353 (314)
ParABS System in Chromosome Partitioning in the Bacterium Myxococcus xanthus
PLoS ONE, 2014 Chromosome segregation is an essential cellular function in eukaryotic and prokaryotic cells. The ParABS system is a fundamental player for a mitosis-like process in chromosome partitioning in many bacterial species. This work shows that the social bacterium Myxococcus xanthus also uses the ParABS system for chromosome segregation.
Antonio A. Iniesta
openalex +5 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Mechanism of chromosome partitioning in Escherichia coli.
Seibutsu Butsuri, 1990 Replicated daughter chromosomes in Escherichia coli move nonprogressively and abruptly from midcell toward the quarter positions at the early D (division) period. The chromosome positioning is controlled by the mukA and mukB gene products. The mukA (tolC) gene encodes an outer membrane protein.
Sota HIRAGA, Hironori NIKI
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Characterization of a prokaryotic SMC protein involved in chromosome partitioning [PDF]
Genes & Development, 1998 smc of Bacillus subtilis encodes a homolog of eukaryotic SMC proteins involved in chromosome condensation, pairing, and partitioning. A null mutation in B. subtilis smc caused a temperature-sensitive-lethal phenotype in rich medium. Under permissive conditions, the mutant had abnormal nucleoids, approximately 10% of the cells were anucleate, and ...
R A, Britton, D C, Lin, A D, Grossman
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Haplotype Assembly: An Information Theoretic View
, 2014 This paper studies the haplotype assembly problem from an information theoretic perspective. A haplotype is a sequence of nucleotide bases on a chromosome, often conveniently represented by a binary string, that differ from the bases in the corresponding
Si, Hongbo +2 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Chromosome partition in Escherichia coli requires postreplication protein synthesis
Journal of Bacteriology, 1989 After inhibition of protein synthesis, the number of nuclear bodies (nucleoids) visible in cells of Escherichia coli B/rA corresponded closely to the number of completely replicated chromosomes. We calculated that nucleoid partition follows almost immediately after replication forks reach the chromosome terminus.
W D, Donachie, K J, Begg
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Divide Precisely and Proliferate Safely: Lessons From Budding Yeast
Frontiers in Genetics, 2019 A faithful cell division is essential for proper cellular proliferation of all eukaryotic cells; indeed the correct segregation of the genetic material allows daughter cells to proceed into the cell cycle safely.
Roberta Fraschini
doaj +1 more source
Using a genetic algorithm for optimizing the functional decomposition of multiple-valued functions [PDF]
, 1997 The genetic algorithm which determines the good functional decomposition of multiple-valued logic functions is presented. The algorithm expands the range of searching for a best decomposition, providing the optimal column multiplicity.
Kalganova, T, Kochergov, E, Strechen, N
core
, 2010 The mapping between genotype and phenotype is encoded in the complex web of epistatic interaction between genetic loci. In this rugged fitness landscape, recombination processes, which tend to increase variation in the population, compete with selection ...
A. Hartmann +18 more
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