Results 71 to 80 of about 476,637 (284)
X chromosome inactivation during Drosophila spermatogenesis [PDF]
, 2007 Genes with male- and testis-enriched expression are under-represented on the Drosophila melanogaster X chromosome. There is also an excess of retrotransposed genes, many of which are expressed in testis, that have “escaped” the X chromosome and moved to ...
Baines, J. +11 more
core +2 more sources
Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control
Advanced Materials Interfaces, EarlyView.In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah +8 more
wiley +1 more source
Psammaplysin F: A unique inhibitor of bacterial chromosomal partitioning
Bioorganic & Medicinal Chemistry Letters, 2013 Described is the antibiotic activity of a marine natural product. Psammaplysin F (1) inhibited the growth of four Gram-positive strains by >80% at 50μM, and the amine at position C-20 is responsible for the observed antibacterial activity. When tested against two strains of methicillin resistant Staphylococcus aureus (MRSA), the minimum inhibitory ...
Ramsey, DM +6 more
openaire +3 more sources
Septal localization of the SpoIIIE chromosome partitioning protein in Bacillus subtilis [PDF]
The EMBO Journal, 1997 The 787 amino acid SpoIIIE protein of Bacillus subtilis is required for chromosome partitioning during sporulation. This process differs from vegetative chromosome partitioning in that it occurs after formation of the septum, apparently by transfer of the chromosome through the nascent septum in a manner reminiscent of plasmid conjugation. Here we show
Wu LJ, Errington J
openaire +3 more sources
Epigenetics & Chromatin, 2018 Background During sexual reproduction in the unicellular ciliate Stylonychia somatic macronuclei differentiate from germline micronuclei. Thereby, programmed sequence reduction takes place, leading to the elimination of > 95% of germline sequences, which
Jan Postberg +5 more
doaj +1 more source
Endogenous 2μ Plasmid Editing for Pathway Engineering in Saccharomyces cerevisiae
Frontiers in Microbiology, 2021 In Saccharomyces cerevisiae, conventional 2μ-plasmid based plasmid (pC2μ, such as pRS425) have been widely adopted in pathway engineering for multi-copy overexpression of key genes. However, the loss of partition and copy number control elements of yeast
Bo-Xuan Zeng +11 more
doaj +1 more source
Advanced Science, EarlyView.The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang +20 more
wiley +1 more source
Micellar chromatographic partition coefficients and their application in predicting skin permeability [PDF]
The major goal for physicochemical screening of pharmaceuticals is to predict human drug absorption, distribution, elimination, excretion and toxicity.
Shahzad, Yasser
core +3 more sources
Advanced Science, EarlyView.Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen +19 more
wiley +1 more source