Results 11 to 20 of about 693,747 (160)
Dynamic Distribution of SeqA Protein across the Chromosome of
mBio, 2010 The bacterial SeqA protein binds to hemi-methylated GATC sequences that arise in newly synthesized DNA upon passage of the replication machinery. In Escherichia coli K-12, the single replication origin oriC is a well-characterized target for SeqA, which ...
María Antonia Sánchez-Romero +5 more
doaj +2 more sources
Dynamics of DNA replication during premeiosis and early meiosis in wheat. [PDF]
PLoS ONE, 2014 Meiosis is a specialised cell division that involves chromosome replication, two rounds of chromosome segregation and results in the formation of the gametes.
María-Dolores Rey, Pilar Prieto
doaj +1 more source
Mathematical modelling of whole chromosome replication [PDF]
, 2010 All chromosomes must be completely replicated prior to cell division, a requirement that demands the activation of a sufficient number of appropriately distributed DNA replication origins.
de Moura, Alessandro P.S. +4 more
core +1 more source
Genome Biology, 2022 Background A major driver of cancer chromosomal instability is replication stress, the slowing or stalling of DNA replication. How replication stress and genomic instability are connected is not known.
Nadeem Shaikh +11 more
doaj +1 more source
Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos [PDF]
, 2015 During cell division, chromatin alternates between a condensed state to facilitate chromosome segregation and a decondensed form when DNA replicates.
Blow, J. Julian; id_orcid +11 more
core +1 more source
Neoplasia: An International Journal for Oncology Research, 2008 Cdc7 is a conserved serine/threonine kinase essential for the initiation of DNA replication, likely by activating the MCM DNA helicase at the G1- to S-phase transition.
Dorine Bonte +5 more
doaj +1 more source
Replication fork collisions cause pathological chromosomal amplification in cells lacking RecG DNA translocase [PDF]
, 2009 This is an open access article, shared under a Creative Commons licence. Copyright © 2009 The Authors.Duplication and transmission of chromosomes require precise control of chromosome replication and segregation.
Lloyd, RG +4 more
core +1 more source
Chromosome structuring limits genome plasticity in Escherichia coli. [PDF]
PLoS Genetics, 2007 Chromosome organizations of related bacterial genera are well conserved despite a very long divergence period. We have assessed the forces limiting bacterial genome plasticity in Escherichia coli by measuring the respective effect of altering different ...
Emilie Esnault +3 more
doaj +1 more source
Pathological replication in cells lacking RecG DNA translocase [PDF]
, 2009 This is an open access article, shared under a Creative Commons licence. Copyright © 2009 The Authors.Little is known about what happens when forks meet to complete DNA replication in any organism.
Lloyd, RG +7 more
core +1 more source
Cloning, expression, and chromosomal localization of the 140-kilodalton subunit of replication factor C from mice and humans [PDF]
, 1994 We have isolated a full-length mouse cDNA encoding a lysine-rich protein of 1,131 amino acids with a calculated molecular mass of 126 kDa. The protein binds in a sequence-unspecific manner to DNA, is localized exclusively in the nucleus, and contains a ...
Schütz, Günther +6 more
core +2 more sources