Results 91 to 100 of about 97,446 (236)

COMMENT ON “A PARTIAL TRISOMY 9 CASE WITH DICENTRIC CHROMOSOME DUE TO THE ADJACENT-2 SEGREGATION OF MATERNAL RECIPROCAL TRANSLOCATION”

open access: yesİstanbul Tıp Fakültesi Dergisi
Dear Editor, We have read the article entitled “A partial trisomy 9 case with dicentric chromosome due to the adjacent-2 segregation of maternal reciprocal translocation” by Urtekin et al.
Juan Pablo Meza-espınoza   +2 more
doaj   +1 more source

Methylated histones on mitotic chromosomes promote topoisomerase IIα function for high fidelity chromosome segregation

open access: yesiScience, 2023
Summary: DNA Topoisomerase IIα (TopoIIα) decatenates sister chromatids, allowing their segregation in mitosis. Without the TopoIIα Strand Passage Reaction (SPR), chromosome bridges and ultra-fine DNA bridges (UFBs) arise in anaphase.
Sanjana Sundararajan   +12 more
doaj  

Coordination of Chromosome Segregation and Cell Division in Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2017
Productive bacterial cell division and survival of progeny requires tight coordination between chromosome segregation and cell division to ensure equal partitioning of DNA.
Amy L. Bottomley   +6 more
doaj   +1 more source

Kinetochore-independent chromosome segregation driven by lateral microtubule bundles

open access: yeseLife, 2015
During cell division, chromosomes attach to spindle microtubules at sites called kinetochores, and force generated at the kinetochore-microtubule interface is the main driver of chromosome movement.
Christina C Muscat   +4 more
doaj   +1 more source

Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells

open access: yesCell Reports, 2016
Karyotype diversity is a hallmark of solid tumors that contributes to intratumor heterogeneity. This diversity is generated by persistent chromosome mis-segregation associated with chromosomal instability (CIN).
Bernardo Orr   +4 more
doaj   +1 more source

Motorized Chromosome Models of Mitosis [PDF]

open access: yesarXiv
During mitosis, near-spherical chromosomes reconfigure into rod-like structures to ensure their accurate segregation to daughter cells. We explore here, the interplay between the nonequilibrium activity of molecular motors in determining the chromosomal organization in mitosis and its characteristic symmetry-breaking events.
arxiv  

Ancestral inference from haplotypes and mutations [PDF]

open access: yesarXiv, 2017
We consider inference about the history of a sample of DNA sequences, conditional upon the haplotype counts and the number of segregating sites observed at the present time. After deriving some theoretical results in the coalescent setting, we implement rejection sampling and importance sampling schemes to perform the inference. The importance sampling
arxiv  

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