Results 91 to 100 of about 923,115 (353)

Manipulating Unisexual–Sexual Reproduction Transition to Engineer Genome‐Reconstructed Polyploids

open access: yesAdvanced Science, EarlyView.
This study developed an efficient approach to generate genome‐reconstructed polyploids involving unisexual gynogenetic Carassius gibelio, sexual C. auratus, and sexual C. cuvieri. The selected superior clone inherited gynogenesis ability of C. gibelio and herpesvirus resistance of wild C.
Meng Lu   +9 more
wiley   +1 more source

Entropy as the driver of chromosome segregation [PDF]

open access: yesNature Reviews Microbiology, 2010
We present a new physical biology approach to understanding the relationship between the organization and segregation of bacterial chromosomes. We posit that replicated Escherichia coli daughter strands will spontaneously demix as a result of entropic forces, despite their strong confinement within the cell; in other words, we propose that entropy can ...
Andrew Wright, Suckjoon Jun
openaire   +2 more sources

Insensitivity of Chromosome I and the Cell Cycle to Blockage of Replication and Segregation of Vibrio cholerae Chromosome II

open access: yesmBio, 2012
Vibrio cholerae has two chromosomes (chrI and chrII) whose replication and segregation are under different genetic controls. The region covering the replication origin of chrI resembles that of the Escherichia coli chromosome, and both origins are under ...
Ryosuke Kadoya, Dhruba K. Chattoraj
doaj   +1 more source

Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep

open access: yesAdvanced Science, EarlyView.
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu   +12 more
wiley   +1 more source

Chromosome segregation machinery and cancer [PDF]

open access: yesCancer Science, 2009
Loss or gain of chromosomes is associated with many cancer cells. This property, called chromosome instability, might arise from a lesion in the chromosome segregation machinery. Essential for chromosome segregation are the proper connection of microtubules to kinetochores, and the synchronous segregation of sister chromatids in anaphase.
Kozo Tanaka, Toru Hirota
openaire   +3 more sources

Alternating Dynamics of oriC, SMC, and MksBEF in Segregation of Pseudomonas aeruginosa Chromosome

open access: yesmSphere, 2020
Condensins are essential for global chromosome organization in diverse bacteria. Atypically, the Pseudomonas aeruginosa chromosome encodes condensins from two superfamilies, SMC-ScpAB and MksBEF.
Hang Zhao   +3 more
doaj   +1 more source

Coordination of Chromosome Segregation and Cell Division in Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2017
Productive bacterial cell division and survival of progeny requires tight coordination between chromosome segregation and cell division to ensure equal partitioning of DNA.
Amy L. Bottomley   +6 more
semanticscholar   +1 more source

m6A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post‐Transcriptional Control

open access: yesAdvanced Science, EarlyView.
As an m6A reader, hnRNPA2B1 predominantly regulates specific transcripts (e.g., Ep400, Rrs1) that are essential for chromosome organization and remodeling in an m6A‐dependent manner. Furthermore, it is demonstrated to interact with factors involved in mRNA processing and translation. This dual functionality is pivotal for ensuring the proper occurrence
Lisha Yin   +11 more
wiley   +1 more source

Loop-extruders alter bacterial chromosome topology to direct entropic forces for segregation

open access: yesNature Communications
Entropic forces have been argued to drive bacterial chromosome segregation during replication. In many bacterial species, however, specifically evolved mechanisms, such as loop-extruding SMC complexes and the ParABS origin segregation system, contribute ...
Janni Harju   +2 more
doaj   +1 more source

Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation

open access: yesJournal of Molecular Cell Biology, 2017
Stable transmission of genetic information during cell division requires faithful mitotic spindle assembly and chromosome segregation. The Ran GTPase plays a key role in mitotic spindle assembly.
Xiaolin Bao   +19 more
semanticscholar   +1 more source

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