Pedigree reconstruction for triploid apple cultivars using single nucleotide polymorphism array data
Many economically, culturally, and historically important apple cultivars are triploids, which have three copies of each chromosome instead of the more typical two copies in diploids. Despite their prevalence and importance, there have been conflicting reports regarding their origin and their ability to beget diploids.
Nicholas P. Howard+7 more
wiley +1 more source
Using Fluorescence Recovery After Photobleaching (FRAP) to study dynamics of the Structural Maintenance of Chromosome (SMC) complex in vivo [PDF]
The SMC complex, MukBEF, is important for chromosome organization and segregation in Escherichia coli. Fluorescently tagged MukBEF forms distinct spots (or 'foci') in the cell, where it is thought to carry out most of its chromosome associated activities.
arxiv
Breeding and selection of taro (Colocasia esculenta) for improved disease‐resistance in Hawaiʻi
Taro is a root crop with wide geographic range and high cultural significance to Indigenous peoples of Hawaiʻi and the Pacific. Taro Leaf Blight (TLB) is a worldwide disease of taro, and Hawaiian taro varieties exhibited little resistance to it. To improve TLB‐resistance, conventional breeding was conducted by hand‐pollination.
Roshan Paudel+13 more
wiley +1 more source
Brain Metabolic Features of FUS‐ALS: A 2‐[18F]FDG‐PET Study
Objective We aimed at evaluating the brain metabolic features of fused in sarcoma amyotrophic lateral sclerosis (FUS‐ALS) compared with sporadic ALS (sALS), using 2‐[fluorine‐18] fluoro‐2‐deoxy‐D‐glucose positron emission tomography (2‐[18F]FDG‐PET). Methods We employed the 2‐sample t‐test model of SPM12, implemented in MATLAB, to compare 12 FUS‐ALS ...
Antonio Canosa+24 more
wiley +1 more source
UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer
Defects in mitosis can lead to aneuploidy, which is a common feature of human cancers. Spindle Assembly Checkpoint (SAC) controls fidelity of chromosome segregation in mitosis to prevent aneuploidy. The ubiquitin receptor protein Ubiquitin Associated and
Ksenia Krupina+5 more
doaj +1 more source
Coordination of Chromosome Segregation and Cell Division in Staphylococcus aureus
Productive bacterial cell division and survival of progeny requires tight coordination between chromosome segregation and cell division to ensure equal partitioning of DNA.
Amy L. Bottomley+6 more
doaj +1 more source
Confinement-induced glassy dynamics in a model for chromosome organization [PDF]
Recent experiments showing scaling of the intrachromosomal contact probability, $P(s)\sim s^{-1}$ with the genomic distance $s$, are interpreted to mean a self-similar fractal-like chromosome organization. However, scaling of $P(s)$ varies across organisms, requiring an explanation.
arxiv
Non-random Mis-segregation of Human Chromosomes
Summary: A common assumption is that human chromosomes carry equal chances of mis-segregation during compromised cell division. Human chromosomes vary in multiple parameters that might generate bias, but technological limitations have precluded a ...
Joseph Thomas Worrall+9 more
doaj
Impact of crowders on the morphology of bacterial chromosomes [PDF]
Inspired by recent experiments on the effects of cytosolic crowders on the organization of bacterial chromosomes, we consider a "feather-boa" type model chromosome in the presence of non-additive crowders, encapsulated within a cylindrical cell. We observe spontaneous emergence of complementary helicity of the confined polymer and crowders.
arxiv
Shennong 1 Chicken 40K Liquid Chip: Advancing Genetic Research in Chinese Indigenous Chickens
Based on comprehensive genomic data of Chinese indigenous chickens, we developed a specialized genotyping array for this population. Comparative analyses with published mainstream arrays and evaluations, including genetic assessment of diverse chicken types and gene mining analyses, demonstrated its superior applicability to Chinese indigenous chickens.
Chaoqun Gao+14 more
wiley +1 more source