Results 151 to 160 of about 94,426 (241)

Autophagy-related protein Atg11 is essential for microtubule-mediated chromosome segregation. [PDF]

PLoS Biol
Reza MH, Aggarwal R, Verma J, Podh NK, Chowdhury R, Mehta G, Manjithaya R, Sanyal K.   +7 more
europepmc   +1 more source

Different nontarget‐site mechanisms underlie resistance to dicamba and 2,4‐D in an Amaranthus tuberculatus population

Pest Management Science, EarlyView.
Weak phenotypic and genetic associations between resistance to dicamba and 2,4‐D suggest that different nontarget‐site mechanisms contribute to these traits in an Amaranthus tuberculatus population from Illinois. Abstract BACKGROUND Amaranthus tuberculatus (Moq.) Sauer (waterhemp) has emerged as one of several weed species that is resistant to ...
Isabel Schlegel Werle, Lucas Kopecky Bobadilla, Damilola A Raiyemo, Alexander J Lopez, Filipi Mesquita Machado, Patrick J Tranel   +5 more
wiley   +1 more source

Mechanisms, Machinery, and Dynamics of Chromosome Segregation in Zea mays. [PDF]

Genes (Basel)
Duffy ME, Ngaw M, Polsky SE, Marzec AE, Zhang SS, Dzierzgowski OR, Nannas NJ.   +6 more
europepmc   +1 more source

A point mutation in IAA34 confers resistance to the auxin herbicide 2,4‐D in Sisymbrium orientale

Pest Management Science, EarlyView.
A point mutation in domain IV of SoAux/IAA34‐R provides resistance to 2,4‐D. Abstract BACKGROUND Sisymbrium orientale has evolved resistance to 2,4‐D in Australia due to a 27 bp deletion in SoIAA2. However, one population of Sisymbrium orientale resistant to 2,4‐D (R1) did not contain the SoIAA2Δ27, suggesting another 2,4‐D resistance mechanism was ...
Yuanlin Qi, Mahima Krishnan, Matthew Tucker, Christopher Preston   +3 more
wiley   +1 more source

A novel variant in GATM causes idiopathic renal Fanconi syndrome and predicts progression to end‐stage kidney disease

Clinical Genetics, Volume 103, Issue 2, Page 214-218, February 2023., 2023
Whole exome sequencing of a mother and daughter with isolated Fanconi syndrome revealed a novel variant of GATM, c.965G>C p.(Arg322Pro). Molecular dynamic simulation confirmed that the abnormal protein product would tend to form multimers likely to disrupt mitochondrial function.
Eleanor G. Seaby, Steven Turner, David J. Bunyan, Fariba Seyed‐Rezai, Jonathan Essex, Rodney D. Gilbert, Sarah Ennis   +6 more
wiley   +1 more source

SRBD1 facilitates chromosome segregation by promoting topoisomerase IIα localization to mitotic chromosomes. [PDF]

Nat Commun
Lovejoy CA, Wessel SR, Bhowmick R, Hatoyama Y, Kanemaki MT, Zhao R, Cortez D.   +6 more
europepmc   +1 more source

Delineation of the clinical profile of CNOT2 haploinsufficiency and overview of the IDNADFS phenotype

Clinical Genetics, Volume 103, Issue 2, Page 156-166, February 2023., 2023
Abstract CNOT2 haploinsufficiency underlies a rare neurodevelopmental disorder named Intellectual Developmental disorder with NAsal speech, Dysmorphic Facies, and variable Skeletal anomalies (IDNADFS, OMIM 618608). The condition clinically overlaps with chromosome 12q15 deletion syndrome, suggesting a major contribution of CNOT2 haploinsufficiency to ...
Marcello Niceta, Simone Pizzi, Francesca Inzana, Angela Peron, Somayeh Bakhtiari, Mathilde Nizon, Jonathan Levy, Cecilia Mancini, Benjamin Cogné, Francesca Clementina Radio, Emanuele Agolini, Dario Cocciadiferro, Antonio Novelli, Mustafa A. Salih, Maria Paola Recalcati, Rosangela Arancio, Marianne Besnard, Anne‐Claude Tabet, Michael C. Kruer, Manuela Priolo, Bruno Dallapiccola, Marco Tartaglia   +21 more
wiley   +1 more source

An Aurora kinase A-BOD1L1-PP2A B56 axis promotes chromosome segregation fidelity. [PDF]

Cell Rep
Kucharski TJ, Vlasac IM, Lyalina T, Higgs MR, Christensen BC, Bechstedt S, Compton DA.   +6 more
europepmc   +1 more source

Recurrent missense variants in clonal hematopoiesis‐related genes present in the general population

Clinical Genetics, Volume 103, Issue 2, Page 247-251, February 2023., 2023
A survey of recurrent somatic missense variants in DNMT3A, SF3B1, SRSF2 and TP53, prominent genes underlying clonal hematopoiesis of indeterminate potential (CHIP), in gnomAD noncancer database shows the presence of tens of variants. Their pervasive presence in blood DNA from elder individuals is compatible with CHIP of somatic origin.
Olivier Ariste, Pierre de la Grange, Reiner A. Veitia   +2 more
wiley   +1 more source

Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation. [PDF]

Nat Commun
Black EM, Ramírez Parrado CA, Trier I, Li W, Joo YK, Pichurin J, Liu Y, Kabeche L.   +7 more
europepmc   +1 more source