Results 181 to 190 of about 187,172 (325)

Multiomics Reveal Associations Between CpG Methylation, Histone Modifications and Transcription in a Species That has Lost DNMT3, the Colorado Potato Beetle

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Despite lacking DNMT3, EM‐seq revealed CpG methylation in the Colorado potato beetle. CUT&Tag analysis showed an association of H3K36me3 and H3K27ac with transcription, with H3K36me3 mirroring CpG methylation, demonstrating epigenetic flexibility.
Zoe M. Länger   +6 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Mitotic exit in mammalian cells

open access: yesMolecular Systems Biology, 2009
Orsolya Kapuy   +3 more
doaj   +1 more source

Recently Evolved, Stage‐Specific Genes Are Enriched at Life‐Stage Transitions in Flies

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
We discovered that 20%–30% of protein‐coding genes in Drosophila melanogaster and Aedes aegypti are only expressed during specific stages of development. Surprisingly, many of these stage‐specific genes are newly evolved, unique to flies and mosquitoes, shedding light on how insect development has evolved over time.
Andreas Remmel   +3 more
wiley   +1 more source

GAA‐FGF14 Expansions and CACNA1A Variants: Phenotypic Overlap and Diagnostic Implications

open access: yesMovement Disorders, EarlyView.
Abstract Background An intronic (GAA)•(TTC) repeat expansion in FGF14 was recently identified as the cause of spinocerebellar ataxia 27B (SCA27B), a disorder presenting with both chronic cerebellar ataxia and episodic symptoms. The phenotype of SCA27B overlaps with that of CACNA1A spectrum disorders.
Elisabetta Indelicato   +11 more
wiley   +1 more source

Ensuring fidelity of chromosome segregation

open access: yesMolecular Biology of the Cell, 2018
Ünal, Elçin, Torres, Jorge Z
openaire   +4 more sources

Compound Heterozygous Structural Variants in Cases with Unsolved PRKN‐Associated Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Biallelic mutations in the PRKN gene are a common cause of early‐onset Parkinson's disease (EOPD). In addition to single nucleotide variants, structural variants contribute substantially to the mutational profile of PRKN. A significant portion of patients with EOPD remains genetically unsolved.
Agata Fant   +24 more
wiley   +1 more source

Chromosome segregation dynamics during the cell cycle of Staphylococcus aureus. [PDF]

open access: yesNat Commun
Izquierdo-Martinez A   +8 more
europepmc   +1 more source

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