Results 181 to 190 of about 94,426 (241)

Validating a Target‐Enrichment Design for Capturing Uniparental Haplotypes in Ancient Domesticated Animals

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT In the last three decades, DNA sequencing of ancient animal osteological assemblages has become an important tool complementing standard archaeozoological approaches to reconstruct the history of animal domestication. However, osteological assemblages of key archaeological contexts are not always available or do not necessarily preserve enough
Kuldeep D. More   +64 more
wiley   +1 more source

The role of DNA topoisomerase 1α (AtTOP1α) in regulating arabidopsis meiotic recombination and chromosome segregation. [PDF]

open access: yesPeerJ
Elesawi IE   +10 more
europepmc   +1 more source

Optimization and Evaluation of the bestRAD Sequencing Approach: Towards Ascertainment of the Invasion Routes of the Oriental Fruit Fly, Bactrocera dorsalis

open access: yesMolecular Ecology Resources, EarlyView.
ABSTRACT The bestRAD technique is a reduced genome representation approach with high‐capacity sample multiplexing and physical isolation of biotin‐labelled target DNA fragments using streptavidin beads, which should reduce total cost and genotyping errors. While we here formalise the relevance of this approach within the HTS landscape, our foremost aim
Emeline Charbonnel   +7 more
wiley   +1 more source

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt‐Dependent NAD+ De Novo Synthesis in Mice

open access: yesAging Cell, EarlyView.
In Qprt‐deficient mice, testicular NAD+ levels decline accelerated with age, leading to mitochondrial dysfunction, disrupted DSB repair, impaired meiotic sex chromosome inactivation, and germ cell loss. Nicotinamide riboside (NR) supplementation restores NAD+ levels and alleviates these defects, highlighting the importance of NAD+ de novo synthesis in ...
Yining Xu   +9 more
wiley   +1 more source

Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress. [PDF]

open access: yesNat Commun
de Jaime-Soguero A   +27 more
europepmc   +1 more source

Identifying Age‐Modulating Compounds Using a Novel Computational Framework for Evaluating Transcriptional Age

open access: yesAging Cell, EarlyView.
RNAge is a transcriptional based computational approach to measure changes in cellular age upon experimental manipulation. In silico screening of a database of transcriptional changes from drug perturbations identified a novel aging agent that was applied to an hPSC model of neurodegenerative disease to trigger a late‐onset phenotype.
Chao Zhang   +8 more
wiley   +1 more source

Chromosome segregation dynamics during the cell cycle ofStaphylococcus aureus

open access: yes
Izquierdo-Martinez A   +8 more
europepmc   +1 more source

Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes. [PDF]

open access: yesMol Biol Cell
Joshi JN   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy