Results 231 to 240 of about 1,033,685 (362)

Author response: Pathogenic mutations in the chromokinesin KIF22 disrupt anaphase chromosome segregation

, 2022
Alex F. Thompson, Patrick R. Blackburn, Noah S Arons, Sarah N Stevens, Dusica Babovic‐Vuksanovic, Jane B. Lian, Eric W. Klee, Jason Stumpff   +7 more
openalex   +1 more source

Rare but Relevant? Assessing Variants in Dystonia‐Linked Genes in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Dystonia and Parkinson's disease (PD) exhibit clinical and genetic overlap, but the relevance of dystonia gene variants in PD remains unclear. Objective The aim was to assess the frequency of dystonia‐linked pathogenic variants in PD.
Lara M. Lange, Zih‐Hua Fang, Laurel Screven, Ai Huey Tan, Roy N. Alcalay, Rim Amouri, Roberta Bovenzi, Matilda Fenn, Joshua L.I. Frost, Joseph Jankovic, Simona Jasaityte, Zane Jaunmuktane, Beomseok Jeon, Ignacio Juan Keller Sarmiento, Rejko Krüger, Gregor Kuhlenbäumer, Chin‐Hsien Lin, Lukas Pavelka, Maria Teresa Periñan, Samia Ben Sassi, Tommaso Schirinzi, Jung Hwan Shin, Joshua M. Shulman, Yi Wen Tay, Ryan Uitti, Tom Warner, Zbigniew K. Wszolek, Lesley Wu, Ruey‐Meei Wu, Kirsten E. Zeuner, Cornelis Blauwendraat, Andrew Singleton, Niccolò E. Mencacci, Huw R. Morris, Shen‐Yang Lim, Katja Lohmann, Christine Klein, the Global Parkinson's Genetics Program (GP2)   +37 more
wiley   +1 more source

Mitotic Phosphorylation of Swi6/HP1 Regulates Its Chromatin Binding and Chromosome Segregation. [PDF]

FASEB J
Yoshimura Y, Hayashi A, Tanaka M, Suzuki-Matsubara M, Nakagawa R, Nishibuchi G, Tagami H, Oki M, Nakayama JI.   +8 more
europepmc   +1 more source

Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture

Cell, 2018
Kristin A. Knouse, Kristina E. Lopez, Marc Bachofner, A. Amon   +3 more
semanticscholar   +1 more source

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Nucleosome interaction of the CPC secures centromeric chromatin integrity and chromosome segregation fidelity. [PDF]

EMBO J
Gireesh A, Abad MA, Nozawa RS, Sotelo-Parrilla P, Dury LC, Likhodeeva M, Wear M, Spanos C, Peralta CC, Rappsilber J, Hopfner KP, Wilson MD, Vanderlinden W, Hirota T, Jeyaprakash AA.   +14 more
europepmc   +1 more source

eLife Assessment: Redistribution of fragmented mitochondria ensure symmetric organelle partitioning and faithful chromosome segregation in mitotic mouse zygotes

Evelyn E. Telfer
openalex   +1 more source

Chromosome Segregation and Cell Division Defects in recBC sbcBC ruvC Mutants of Escherichia coli [PDF]

, 1999
Davor Zahradka, Ksenija Vlahović, Mirjana Petranović, Drago Petranović   +3 more
openalex   +1 more source

Author response: Wolbachia action in the sperm produces developmentally deferred chromosome segregation defects during the Drosophila mid-blastula transition

, 2022
Brandt Warecki, Simon Titen, Mohammad Shahriyar Alam, Giovanni Vega, Nassim Lemseffer, Karen Hug, Jonathan S. Minden, William Sullivan   +7 more
openalex   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source