Results 331 to 340 of about 1,021,502 (366)

Inhibitor of Chromosome Segregation in <i>Pseudomonas aeruginosa</i> from Fungal Extracts. [PDF]

ACS Chem Biol
Zhao H, Peramuna T, Ajmal S, Wendt KL, Petrushenko ZM, Premachandra K, Cichewicz RH, Rybenkov VV.   +7 more
europepmc   +1 more source

Decoding the Molecular Landscape of Prepubertal Oocyte Maturation: GTPBP4 as a Key Driver of In Vitro Developmental Competence

Cell Proliferation, EarlyView.
Transcriptional and translational characteristics during goat oocyte maturation and identification of key factors, including GTPBP4, for prepubertal goat oocyte maturation. ABSTRACT The intricate mechanisms driving oocyte maturation remain only partially understood, especially within the domains of domestic animal reproduction and translational ...
Jianpeng Qin, Yaozong Wei, Ao Ning, Wenqi Hu, Pengcheng Wan, Beijia Cao, Bo Pan, Tianyi Lv, Kunlin Du, Xueling Yao, Shuqi Zou, Xiangyi Chen, Shengqin Zang, Jiangfeng Ye, Guozhi Yu, Qiuxia Liang, Liuhong Shen, Lin Zhang, Xiang Chen, Keren Cheng, Li Meng, Guangbin Zhou   +21 more
wiley   +1 more source

Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress. [PDF]

Nat Commun
de Jaime-Soguero A, Hattemer J, Bufe A, Haas A, van den Berg J, van Batenburg V, Das B, di Marco B, Androulaki S, Böhly N, Landry JJM, Schoell B, Rosa VS, Villacorta L, Baskan Y, Trapp M, Benes V, Chabes A, Shahbazi M, Jauch A, Engel U, Patrizi A, Sotillo R, van Oudenaarden A, Bageritz J, Alfonso J, Bastians H, Acebrón SP.   +27 more
europepmc   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

Cell Proliferation, EarlyView.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao, Chi Zhang, Zuo‐Qi Deng, Yue‐xin Qiu, Zhao Zhang, Heng‐Yu Fan, Jing Li, Hong‐Bo Wu   +7 more
wiley   +1 more source

Unraveling the structure and function of a novel SegC protein interacting with the SegAB chromosome segregation complex in Archaea. [PDF]

Nucleic Acids Res
Lin MG, Yen CY, Shen YY, Huang YS, Ng IW, Barillà D, Sun YJ, Hsiao CD.   +7 more
europepmc   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

Cell Proliferation, EarlyView.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie, Ting Wang, Xin‐ran Liu, Yan Wang, Qin Dang, Tian Ding, Jia‐qi Xu, Xian‐jun Yu, Hai Lin, Xiao‐wu Xu, Yi Qin   +10 more
wiley   +1 more source

CAMSAP2 is required for bridging fiber assembly to ensure mitotic spindle assembly and chromosome segregation in human epithelial Caco-2 cells. [PDF]

PLoS One
Nishizawa N, Arai R, Hiranuma K, Toya M, Sato M.   +4 more
europepmc   +1 more source

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

Developmental Medicine &Child Neurology, EarlyView.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve, Claire‐Marine Bérat, Sylvain Hanein, Cyril Gitiaux, ATAD3 Study Group, Julie Steffann, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia, Brian Sperelakis‐Beedham, Zahra Assouline, Marie‐Thérèse Abi‐Warde, Rukhshona Abdullazoda, Agnès Guichet, Céline Bris, Aurélien Caux, Marlène Rio, Jérémy Bertrand, Pauline Gaignard, Alice Lepelley, Arnold Munnich, Manuel Schiff, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia   +26 more
wiley   +1 more source

Sgo1 interacts with CENP-A to guide accurate chromosome segregation in mitosis. [PDF]

J Mol Cell Biol
Wu F, Akbar H, Wang C, Yuan X, Dou Z, Mullen M, Niu L, Zhang L, Zang J, Wang Z, Yao X, Song X, Liu X.   +12 more
europepmc   +1 more source

Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes. [PDF]

Mol Biol Cell
Joshi JN, Changela N, Mahal L, Jang J, Defosse T, Wang LI, Das A, Shapiro JG, McKim K.   +8 more
europepmc   +1 more source