Results 331 to 340 of about 1,033,685 (362)

A comprehensive overview of yeast libraries and their role in advancing cell biology

The FEBS Journal, EarlyView.
Systematic, genome‐wide yeast mutant libraries have revolutionized systems and cell biology. By allowing high‐throughput interrogation of every gene and protein, they have defined gene essentiality, charted protein localization, illuminated function, mapped interactions, and more.
Din Baruch, Maya Schuldiner, Ofir Klein
wiley   +1 more source

Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomous effects in the B‐cell compartment

The FEBS Journal, EarlyView.
Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver, Rachael Riley Denbrock, Cindy Carolina Martines, Alessandro Didonna   +3 more
wiley   +1 more source

Low-intensity pulsed ultrasound induces multifaced alterations in chromosome segregation, cytoskeletal filaments and cell junctions. [PDF]

Sci Rep
Udroiu I, Todaro F, Vitaliti A, Palmieri D, Guida E, Perilli G, Duranti L, D'Ottavi C, Mattei M, Dolci S, Paradossi G, Bedini A, Silvestri I, Sgura A, Domenici F.   +14 more
europepmc   +1 more source

RB1 inactivation in cutaneous carcinomas

Histopathology, EarlyView.
Among skin carcinomas, recurrent RB1 inactivation is observed in Merkel cell carcinoma, in a subset of squamous cell carcinoma with bowenoid morphology, in sebaceous carcinoma and in the recently described Wnt/beta‐catenin rosette‐forming carcinoma.
Tiffany Liv, Antoine Touzé, David Schrama, Serge Guyétant, Mahtab Samimi, Michael T Tetzlaff, Benjamin A Wood, Paul W Harms, Thibault Kervarrec   +8 more
wiley   +1 more source

Aurora B controls anaphase onset and error-free chromosome segregation in trypanosomes. [PDF]

J Cell Biol
Ballmer D, Lou HJ, Ishii M, Turk BE, Akiyoshi B.   +4 more
europepmc   +1 more source

Eye can see clearly now: Identifying the locus associated with a white‐eye mutation in honey bees (Apis mellifera)

Insect Molecular Biology, EarlyView.
We performed a community science investigation with the beekeepers nationwide to find phenotypic mutants. Alongside a beekeeper in Kentucky, we performed a GWAS to identify a region associated with a white‐eye phenotype. We identified an eight bp region in a non‐coding RNA strongly associated with white eyes.
Riley R. Shultz, Dylan K. Ryals, Phillip Patterson, Jonathan M. Nixon, Izaak R. Gilchrist, Brock A. Harpur   +5 more
wiley   +1 more source

CENP-C-Mis12 complex establishes a regulatory loop through Aurora B for chromosome segregation. [PDF]

Life Sci Alliance
Kong W, Hara M, Tokunaga Y, Okumura K, Hirano Y, Miao J, Takenoshita Y, Hashimoto M, Sasaki H, Fujimori T, Wakabayashi Y, Fukagawa T.   +11 more
europepmc   +1 more source

Developmental expression of Ap‐Vas proteins in aphids and flies reveals their evolutionary roles in insects

Insect Molecular Biology, EarlyView.
Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin, Szu‐Chieh Wang, Charles E. Cook, Ming‐Der Lin, Chun‐che Chang   +4 more
wiley   +1 more source

Inhibitor of Chromosome Segregation in <i>Pseudomonas aeruginosa</i> from Fungal Extracts. [PDF]

ACS Chem Biol
Zhao H, Peramuna T, Ajmal S, Wendt KL, Petrushenko ZM, Premachandra K, Cichewicz RH, Rybenkov VV.   +7 more
europepmc   +1 more source

The role of DNA topoisomerase 1α (AtTOP1α) in regulating arabidopsis meiotic recombination and chromosome segregation. [PDF]

PeerJ
Elesawi IE, Hashem AM, Yao L, Maher M, Hassanin AA, Abd El-Moneim D, Safhi FA, Al Aboud NM, Alshamrani SM, Shehata WF, Chunli C.   +10 more
europepmc   +1 more source