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Segregation of the Bacterial Chromosome
1998Bacteria must successfully complete several processes of the cell cycle to ensure that a single cell will become two viable daughter cells. These processes include: 1) replication of the chromosome, 2) segregation of the chromosomes to opposite poles, and 3) cell division.
Robert A. Britton, James R. Lupski
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Ubiquitin, the centrosome, and chromosome segregation
Chromosome Research, 2015For over a century, the abnormal movement or number of centrosomes has been linked with errors of chromosomes distribution in mitosis. While not essential for the formation of the mitotic spindle, the presence and location of centrosomes has a major influence on the manner in which microtubules interact with the kinetochores of replicated sister ...
Ying Zhang, Paul J. Galardy
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Chromosome Replication and Segregation
2014This chapter reviews our current understanding of bacterial DNA replication and chromosome partitioning in Bacillus subtilis and makes comparisons to Escherichia coli and other organisms where appropriate. Bacterial chromosome replication initiates once per cell division cycle in response to a signal that is tightly coupled to cell mass.
Katherine P. Lemon +3 more
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Chromosome Cohesion and Segregation
2004Eukaryotic cells have multiple chromosomes as carts for the genetic information. In order to ensure faithful reproduction for proliferation in mitosis, or providing an opportunity for genetic reassortment in meiosis, cells must have the ability to deliver their chromosomes properly and in good order to the daughter cells.
Mitsuhiro Yanagida, Kohta Takahashi
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The role of SUMO in chromosome segregation
Chromosoma, 2006Chromosome segregation is an essential feature of the eukaryotic cell cycle. Efficient chromosome segregation requires the co-ordination of several cellular processes; some of which involve gross rearrangements of the overall structure of the genetic material.
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Chromosome Segregation and Aneuploidy
1993Of all genetic afflictions of man, aneuploidy ranks as the most prevalent. Among liveborn babies aneuploidy exist to the extent of about 0.3%, to about 5% among stillborns and a dramatic 25% among miscarriages. The burden is too heavy to be taken lightly.
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Chromosome segregation and cytokinesis in bacteria
Current Opinion in Cell Biology, 1993Substantial progress has recently been made in the understanding of chromosome partitioning and cytokinesis in bacteria. The biochemical properties of some key protein components involved in these processes are beginning to emerge. New evidence supports the recently developed notion that, in prokaryotic cells, basic cell biological processes rely on ...
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The Basics of Chromosome Segregation
2008During cell division, chromosomes carrying thousands of genes are correctly transmitted to daughter cells via a motile apparatus named the mitotic spindle (a schematic outline of the cell (division) cycle is shown in Fig. 2.1). In postreplicative (post S phase) cells, chromosomes comprise duplicated sister chromatids.
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Chromosome Movement and Segregation
1965So far we have discussed only those mechanical changes which affect the morphology of the chromosomes. Here we want briefly to indicate the bodily movements they undergo and which affect their distribution.
Bernard John, Kenneth R. Lewis
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