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Mechanisms for Chromosome Segregation in Bacteria
Frontiers in Microbiology, 2021 The process of DNA segregation, the redistribution of newly replicated genomic material to daughter cells, is a crucial step in the life cycle of all living systems.
Christos Gogou +2 more
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Organization and segregation of bacterial chromosomes [PDF]
Nature Reviews Genetics, 2013 The bacterial chromosome must be compacted more than 1,000-fold to fit into the compartment in which it resides. How it is condensed, organized and ultimately segregated has been a puzzle for over half a century. Recent advances in live-cell imaging and genome-scale analyses have led to new insights into these problems. We argue that the key feature of
Paula Montero Llopis +2 more
openaire +3 more sources
Optically mapping multiple bacterial genomes simultaneously in a single run. [PDF]
PLoS ONE, 2011 Optical mapping of bacterial chromosomes provides an unambiguous low-resolution sequence scaffold of the entire chromosome. In comparison to some techniques, such as pulse field gel electrophoresis, cost and throughput limit the application of this ...
Matthew C Riley +3 more
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Spatial Chromosome Organization and Adaptation of Escherichia coli under Heat Stress
MicroorganismsThe spatial organization of bacterial chromosomes is crucial for cellular functions. It remains unclear how bacterial chromosomes adapt to high-temperature stress.
Xu-Ting Wang, Bin-Guang Ma
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FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Bacterial chromosome segregation by the ParABS system [PDF]
Open Biology, 2020 Proper chromosome segregation during cell division is essential in all domains of life. In the majority of bacterial species, faithful chromosome segregation is mediated by the tripartite ParABS system, consisting of an ATPase protein ParA, a CTPase and DNA-binding protein ParB, and a centromere-likeparSsite.
Adam S. B. Jalal, Tung B. K. Le
openaire +4 more sources
Bacterial artificial chromosomes improve recombinant protein production in mammalian cells
BMC Biotechnology, 2009 Background The development of appropriate expression vectors for large scale protein production constitutes a critical step in recombinant protein production.
Bauer Anton +4 more
doaj +1 more source
Structure of metaphase chromosomes: a role for effects of macromolecular crowding. [PDF]
PLoS ONE, 2012 In metaphase chromosomes, chromatin is compacted to a concentration of several hundred mg/ml by mechanisms which remain elusive. Effects mediated by the ionic environment are considered most frequently because mono- and di-valent cations cause ...
Ronald Hancock
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FEBS Letters, EarlyView.Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel +2 more
wiley +1 more source
The B chromosomes of the African cichlid fish
BMC Genetics, 2010 Background Diverse plant and animal species have B chromosomes, also known as accessory, extra or supernumerary chromosomes. Despite being widely distributed among different taxa, the genomic nature and genetic behavior of B chromosomes are still poorly ...
Martins Cesar +2 more
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