Results 11 to 20 of about 1,217,029 (160)
Erythrocyte phospho-signalling is dynamically altered during infection with Plasmodium falciparum
Microbial Cell, 2020 It is well established that intracellular pathogens mobilise signalling pathways to manipulate gene expression of their host cell to promote their own survival.
Jack D. Adderley, Christian Doerig
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Frontiers in Immunology, 2019 Background: Inflammatory bowel disease (IBD) is characterized by both acute and chronic phase inflammation of the gastro-intestinal (GI) tract that affect a large and growing number of people worldwide with little to no effective treatments.
Matthew Stephens +2 more
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Direct impact of commonly used dietary emulsifiers on human gut microbiota
Microbiome, 2021 Background Epidemiologic evidence and animal studies implicate dietary emulsifiers in contributing to the increased prevalence of diseases associated with intestinal inflammation, including inflammatory bowel diseases and metabolic syndrome.
Sabrine Naimi +3 more
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Microbiome, 2021 Background Studies on the inhibition of inflammation by infection with helminth parasites have, until recently, overlooked a key determinant of health: the gut microbiota.
Adam Shute +9 more
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Gut-innervating TRPV1+ Neurons Drive Chronic Visceral Pain via Microglial P2Y12 ReceptorSummary
Cellular and Molecular Gastroenterology and Hepatology, 2022 Background & Aims: Chronic abdominal pain is a common symptom of inflammatory bowel diseases (IBDs). Peripheral and central mechanisms contribute to the transition from acute to chronic pain during active disease and clinical remission.
Manon Defaye +8 more
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Scientific Reports, 2018 Opioids remain the gold standard for the treatment of moderate to severe pain. However, their analgesic properties come with important side effects, including pruritus, which occurs frequently after systemic or neuraxial administration.
Helvira Melo +6 more
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Inflammation in Chronic Wounds [PDF]
International Journal of Molecular Sciences, 2016 Non-healing chronic wounds present a major biological, psychological, social, and financial burden on both individual patients and the broader health system. Pathologically extensive inflammation plays a major role in the disruption of the normal healing cascade.
Ruilong Zhao +4 more
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Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia
Gut Microbes, 2021 An array of chronic inflammatory diseases, including metabolic diseases such as obesity and diabetes, are thought to be promoted by disturbance of the intestinal microbiota.
Clara Delaroque +3 more
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TLRs and chronic inflammation [PDF]
The International Journal of Biochemistry & Cell Biology, 2010 After the discovery of Toll-like receptors (TLRs), innate immune mechanisms came back in the focus of scientific research. With more and more mechanisms of TLR biology known, it has become clear that these and also other innate immune receptors are not only of crucial importance in the immune response to invading pathogens, but also play a role in the ...
Ospelt, C, Gay, S
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Evaluation of Interleukin17and Interleukin 23 expression in patients with active and latent tuberculosis infection [PDF]
Iranian Journal of Basic Medical Sciences, 2016 Objective(s): Tuberculosis is one of the most important infectious diseases with high mortality rates worldwide, especially in developing countries. Interleukin17 (IL-17) is an important acquired immunity cytokine, which is mainly produced by CD4+TH17 ...
Fatemeh Heidarnezhad +9 more
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