Results 21 to 30 of about 1,856,298 (304)

Serum hyaluronate as a non-invasive marker of hepatic fibrosis and inflammation in HBeAg-negative chronic hepatitis B [PDF]

, 2005
Background: HBV infection is a serious global heath problem. It is crucial to monitor this disease more closely with a non-invasive marker in clinical trials.
Derakhshan, M.H., Estakhri, A., Malekzadeh, R., Mohamadnejad, M., Mohammadkani, A., Montazeri, F., Montazeri, G., Nouri, N., Samiee, S., Zamani, F.   +9 more
core   +4 more sources

Cooperation between host immunity and the gut bacteria is essential for helminth-evoked suppression of colitis

Microbiome, 2021
Background Studies on the inhibition of inflammation by infection with helminth parasites have, until recently, overlooked a key determinant of health: the gut microbiota.
Adam Shute, Blanca E. Callejas, ShuHua Li, Arthur Wang, Timothy S. Jayme, Christina Ohland, Ian A. Lewis, Brian T. Layden, André G. Buret, Derek M. McKay   +9 more
doaj   +1 more source

Gut-innervating TRPV1+ Neurons Drive Chronic Visceral Pain via Microglial P2Y12 ReceptorSummary

Cellular and Molecular Gastroenterology and Hepatology, 2022
Background & Aims: Chronic abdominal pain is a common symptom of inflammatory bowel diseases (IBDs). Peripheral and central mechanisms contribute to the transition from acute to chronic pain during active disease and clinical remission.
Manon Defaye, Nasser S. Abdullah, Mircea Iftinca, Ahmed Hassan, Francina Agosti, Zizhen Zhang, Melissa Cumenal, Gerald W. Zamponi, Christophe Altier   +8 more
doaj   +1 more source

Sphingosine-1-phosphate promotes the persistence of activated CD4 T cells in inflamed sites [PDF]

, 2017
Inflammation can be protective or pathogenic depending on context and timeframe. Acute inflammation, including the accumulation of CD4 T cells, accompanies protective immune responses to pathogens, but the presence of activated CD4 T cells at sites of ...
Ammit, Barnden, Brinkmann, Brown, Chimen, Cyster, Debes, Faust, Firestein, Fu, Garrod, Gibson, Han, Hochreiter-Hufford, Hugues, Jo, Karuppuchamy, Kitano, Ledgerwood, Liao, Limaye, Lindquist, Mackay, Mackay, Mammoto, Masopust, Matloubian, Matsuura, McInnes, Means, Mempel, Mendoza, Murphy, Nowarski, Olivera, Priceman, Pyne, Sawicka, Skon, Smith, Spangrude, Tarrason, Teijeira, Tsunemi, Veres, Wang, Wang   +46 more
core   +3 more sources

Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutic options [PDF]

, 2008
Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis. This hypothesis is supported by an increasing number of reports on the interaction between chronic infection, inflammation, and atherogenesis.
Abbas, M.A., Comi, G, Corea, F, Fawi, G, Galantucci, S, Guenther, A, Kwan, Joseph W.   +6 more
core   +1 more source

Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and alleviated by channel activation

Scientific Reports, 2018
Opioids remain the gold standard for the treatment of moderate to severe pain. However, their analgesic properties come with important side effects, including pruritus, which occurs frequently after systemic or neuraxial administration.
Helvira Melo, Lilian Basso, Mircea Iftinca, Wallace K. MacNaughton, Morley D. Hollenberg, Derek M. McKay, Christophe Altier   +6 more
doaj   +1 more source

The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma [PDF]

, 2016
Chronic asthma is associated with persistent lung inflammation and long-term remodelling of the airways that have proved refractory to conventional treatments such as steroids, despite their efficacy in controlling acute airway contraction and bronchial ...
Al-Riyami, L., Coltherd, J. C., Harnett, M. M., Harnett, W., Lawrie, R. E., Rodgers, D. T., Suckling, C. J.   +6 more
core   +1 more source

Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia

Gut Microbes, 2021
An array of chronic inflammatory diseases, including metabolic diseases such as obesity and diabetes, are thought to be promoted by disturbance of the intestinal microbiota.
Clara Delaroque, Mélissa Chervy, Andrew T. Gewirtz, Benoit Chassaing   +3 more
doaj   +1 more source

Pathogenesis of chronic obstructive pulmonary disease [PDF]

, 2005
The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
core   +2 more sources

Inflammation in Chronic Wounds [PDF]

International Journal of Molecular Sciences, 2016
Non-healing chronic wounds present a major biological, psychological, social, and financial burden on both individual patients and the broader health system. Pathologically extensive inflammation plays a major role in the disruption of the normal healing cascade.
Ruilong Zhao, Helena Liang, Elizabeth Clarke, Christopher Jackson, Meilang Xue   +4 more
openaire   +2 more sources