Results 21 to 30 of about 1,217,029 (160)

Prostaglandins and chronic inflammation [PDF]

Trends in Pharmacological Sciences, 2012
Chronic inflammation is the basis of various chronic illnesses including cancer and vascular diseases. However, much has yet to be learned how inflammation becomes chronic. Prostaglandins (PGs) are well established as mediators of acute inflammation, and recent studies in experimental animals have provided evidence that they also function in transition
Aoki, Tomohiro, Narumiya, Shuh
openaire   +2 more sources

Circadian Oscillations of Minimal Erythema Dose (MED) are Also Influenced by Diet in Patients with Psoriasis: A Chronomedical Study

Dermatology and Therapy, 2023
Introduction Minimal erythema dose (MED) remains a parameter of paramount importance to orient narrow-band (NB)-UVB phototherapy in psoriatic (PsO) patients.
Giovanni Damiani, Alessia Pacifico, Egeria Scoditti, Sara di Gregorio, Massimo Del Fabbro, Claudia Cozzolino, Alessandra Buja, Santo R. Mercuri, Vittoria G. Bianchi, Ayman Grada, Sergio Garbarino, Christopher G. Bunick   +11 more
doaj   +1 more source

Enteric Tuft Cells in Host-Parasite Interactions

Pathogens, 2021
Enteric tuft cells are chemosensory epithelial cells gaining attention in the field of host-parasite interactions. Expressing a repertoire of chemosensing receptors and mediators, these cells have the potential to detect lumen-dwelling helminth and ...
Sruthi Rajeev, Olivia Sosnowski, Shuhua Li, Thibault Allain, André G. Buret, Derek M. McKay   +5 more
doaj   +1 more source

Awareness of organ donation among people living with HIV in Canada: a cross-sectional study

HIV Research & Clinical Practice
Background Advancements in antiretroviral therapy (ART) have significantly increased the life expectancy of people living with HIV, shifting the clinical focus from AIDS-related complications to the management of chronic conditions common in aging ...
Julia Nicholds, Michael Dans, Jonathan B. Angel   +2 more
doaj   +1 more source

ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation

iScience, 2021
Summary: The hypothalamic-pituitary-adrenal (HPA) axis forms a complex neuroendocrine system that regulates the body’s response to stress such as starvation.
Lise Van Wyngene, Tineke Vanderhaeghen, Ioanna Petta, Steven Timmermans, Katrien Corbeels, Bart Van der Schueren, Jolien Vandewalle, Kelly Van Looveren, Charlotte Wallaeys, Melanie Eggermont, Sylviane Dewaele, Leen Catrysse, Geert van Loo, Rudi Beyaert, Roman Vangoitsenhoven, Toshinori Nakayama, Jan Tavernier, Karolien De Bosscher, Claude Libert   +18 more
doaj   +1 more source

Glucocorticoids and chronic inflammation [PDF]

Rheumatology, 2016
Glucocorticoids are steroid hormones that once bound to their receptor interact with the DNA binding domain. Almost 1000-2000 genes are sensitive to their effects, including immune/inflammatory response genes. However, their role in pathophysiology and therapy is still debated.
Rainer H, Straub, Maurizio, Cutolo
openaire   +3 more sources

Single cell mapping identifies a distinct platelet-phenotype in psoriatic type III inflammation

Nature Communications
The understanding of platelet biology is expanding beyond their well-established role in thrombosis and hemostasis to encompass their functions in inflammation.
Katharina S. Kommoss, Sinduya Krishnarajah, Tabea Bieler, Ekaterina Friebel, Lukas Rindlisbacher, Pierluigi Ramadori, Philipp Häne, Shing Kam, Florian Müller, Sandra Prokosch, Ulrike Rothermel, Yunchen Wu, Francesca Barletta, Stefan Czemmel, Sven Nahnsen, Dominic Helm, Martin Schneider, Knut Schäkel, Alexander Enk, Burkhard Becher, Mathias Heikenwälder   +20 more
doaj   +1 more source

Sustained exposure to systemic endotoxin triggers chemokine induction in the brain followed by a rapid influx of leukocytes

Journal of Neuroinflammation, 2020
Background Recent years have seen an explosion of research pertaining to biological psychiatry, yet despite subsequent advances in our understanding of neuroimmune communication pathways, how the brain senses and responds to peripheral inflammation ...
Carolyn A. Thomson, Alison McColl, Gerard J. Graham, Jonathan Cavanagh   +3 more
doaj   +1 more source

Obesity and chronic inflammation crosslinking

Central European Journal of Immunology, 2021
The adipose tissue has been recognized as an active organ involved in numerous metabolic, hormonal and immunological processes. Obesity and associated chronic inflammation leads to many metabolic and autoimmune disorders.
Dorota Artemniak-Wojtowicz, Anna Kucharska, Beata Pyrżak   +2 more
doaj   +1 more source

Chronic Inflammation in Cancer Development [PDF]

Frontiers in Immunology, 2012
Chronic inflammatory mediators exert pleiotropic effects in the development of cancer. On the one hand, inflammation favors carcinogenesis, malignant transformation, tumor growth, invasion, and metastatic spread; on the other hand inflammation can stimulate immune effector mechanisms that might limit tumor growth.
Gabriele eMulthoff, Gabriele eMulthoff, Gabriele eMulthoff, Michael eMolls, Jürgen eRadons   +4 more
openaire   +3 more sources